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IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org, is the global reference in immunogenetics and immunoinformatics, created in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS). IMGT® is a high-quality integrated knowledge resource specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH) of human and other vertebrate species, and in the immunoglobulin superfamily (IgSF), MH superfamily (MhSF) and related proteins of the immune system (RPI) of vertebrates and invertebrates. IMGT® provides a common access to sequence, genome and structure Immunogenetics data, based on the concepts of IMGT-ONTOLOGY and on the IMGT Scientific chart rules. IMGT® works in close collaboration with EBI (Europe), DDBJ (Japan) and NCBI (USA). IMGT® consists of sequence databases, genome database, structure database, and monoclonal antibodies database, Web resources and interactive tools.

IMGT databases

  • IMGT/LIGM-DB (doc) LIGM, Montpellier, France
    Nucleotide sequences of IG and TR from 358 species (196 497 entries)
  • IMGT/MH-DB ANRI, BPRC, hosted at EBI
    Sequences of the human MH (HLA)
  • IMGT/PRIMER-DB (doc) LIGM, Montpellier, France
    Oligonucleotides (primers) of IG and TR from 11 species (1 864 entries)
  • IMGT/CLL-DB (bylaws) LIGM, Montpellier, France
    IG sequences from CLL, an initiative of the IMGT/CLL-DB group
  • IMGT/GENE-DB (doc) LIGM, Montpellier, France
    International nomenclature for IG and TR genes from human, mouse, rat and rabbit (8 349 genes, 11 184 alleles)
  • IMGT/mAb-DB (doc) LIGM, Montpellier, France
    Monoclonal antibodies (IG, mAb), fusion proteins for immune applications (FPIA), composite proteins for clinical applications (CPCA), and related proteins (RPI) of therapeutic interest (1 118 entries)

IMGT tools

IMGT Latest newsrss

  • CAUTION! IMGT web-site may not be available on April 27th, 2021 from 6:00am to 9:00am (GMT:+0200) (Wed, 21 Apr 2021 07:57:33 +0200)
  • New version of IMGT/HighV-QUEST (version 1.8.2) (Thu, 25 Mar 2021 09:45:08 +0100)
  • CAUTION! IMGT web-site may not be available on March 31th, 2021 from 7:00am to 7:00pm (GMT:+0100) (Thu, 25 Mar 2021 11:56:22 +0100)
  • UPDATE 2021: Human (Homo sapiens) IGKV and IGLV in IMGT/GENE-DB, IMGT/LIGM-DB and IMGT Web resources (Fri, 12 Mar 2021 13:35:55 +0100)


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