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IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org, is the global reference in immunogenetics and immunoinformatics, created in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS). IMGT® is a high-quality integrated knowledge resource specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH) of human and other vertebrate species, and in the immunoglobulin superfamily (IgSF), MH superfamily (MhSF) and related proteins of the immune system (RPI) of vertebrates and invertebrates. IMGT® provides a common access to sequence, genome and structure Immunogenetics data, based on the concepts of IMGT-ONTOLOGY and on the IMGT Scientific chart rules. IMGT® works in close collaboration with EBI (Europe), DDBJ (Japan) and NCBI (USA). IMGT® consists of sequence databases, genome database, structure database, and monoclonal antibodies database, Web resources and interactive tools.

IMGT founder and director: Marie-Paule Lefranc (Marie-Paule.Lefranc@igh.cnrs.fr), Université de Montpellier, CNRS, LIGM, IGH, SFR, Montpellier (France)

IMGT databases

  • IMGT/LIGM-DB (doc) LIGM, Montpellier, France
    Nucleotide sequences of IG and TR from 351 species (178 934 entries)
  • IMGT/MH-DB ANRI, BPRC, hosted at EBI
    Sequences of the human MH (HLA)
  • IMGT/PRIMER-DB (doc) LIGM, Montpellier, France
    Oligonucleotides (primers) of IG and TR from 11 species (1 864 entries)
  • IMGT/CLL-DB (bylaws) LIGM, Montpellier, France
    IG sequences from CLL, an initiative of the IMGT/CLL-DB group
  • IMGT/GENE-DB (doc) LIGM, Montpellier, France
    International nomenclature for IG and TR genes from human, mouse, rat and rabbit (4 536 genes, 6 393 alleles)
  • IMGT/mAb-DB (doc) LIGM, Montpellier, France
    Monoclonal antibodies (IG, mAb), fusion proteins for immune applications (FPIA), composite proteins for clinical applications (CPCA), and related proteins (RPI) of therapeutic interest (753 entries)

IMGT tools