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Abbreviations

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

a or A
adenine (purine base of DNA and RNA)
AA
amino acid
Å
angstrom (angström in french) (10-10 meter, 1 Å = 0.1 nm)
Ab
antibody
ACPA
anti-citrullinated protein/peptide antibody
AICDA
activation induced cytidine deaminase (previously: AID, HIGM2)
AID
see AICDA
BcR
B cell receptor (on the surface of mature B cells, comprising mIG associated to the coreceptors CD79A (Ig-alpha, mb-1) and CD79B (Ig-beta, B29))
BER
base excision repair
BM
bone marrow
bp
base pair
BrMRBc
bromelain-treated mouse red blood cells
c or C
cytosine (pyrimidine base of DNA and RNA)
C
constant
CCP
cyclic citrullinated (deiminated) peptide
CCP1, CCP2, CCP3: first, second, third generation anti-CCP assay
cDNA
complementary DNA
CDR
complementarity determining region
CDR-IMGT
complementarity determining region according to IMGT unique numbering
CH
immunoglobulin heavy constant exon or domain
CLL
chronic lymphocytic leukemia
CNRS
Centre National de la Recherche Scientifique
CNS
central nervous system
CO
CONNECTING-REGION (IMGT label)
CPT
citrate/pyridoxal 5'-phosphate/Tris
CSR
class switch recombination
CY
CYTOPLASMIC-REGION (IMGT label)
D
diversity
Da
dalton (1 Da=1.66x10-24 g)
dC
deoxycytidine
DCI
Dénomination Commune Internationale (INN in English)
DDBJ
DNA DataBank of Japan (nucleotide sequence database)
DSB
double-strand break
dsDNA
double-stranded DNA
dU
deoxyuridine
E
enhancer
EBV
Epstein-Barr virus
EDTA
ethylenediamine tetraacetic acid
EMBLBank
European Molecular Biology Laboratory nucleotide sequence database
ENA
European Nucleotide Archive
ER
endoplasmic reticulum
FAM
fluorescein-5-carboxamide (or 5-carboxyfluorescein)
FAQ
frequently asked question
FL
follicular lymphoma
FnSF
fibronectin superfamily
FR
framework region
FR-IMGT
framework region according to IMGT unique numbering
Fv
Fragment variable
g or G
guanine (purine base of DNA and RNA)
Gb
gigabase (109 bases; a billion bases). Unit of length of nucleic acids. For double-stranded DNA, 109 base pairs (see also kb, Mb)
GC
germinal center
gDNA
genomic DNA
GEDI
GenBank/ENA/DDBJ/IMGT/LIGM-DB (previously GenBank/EMBLBank/DDBJ/IMGT/LIGM-DB)
GenBank
US nucleotide sequence database
HCV
hepatitis C virus
HGNC
Human Genome Organisation (HUGO) Nomenclature Committee
HLA
human leucocyte antigen (human MHC)
HUGO
HUman Genome Organisation
IG
immunoglobulin (for locus, gene, chain or receptor)
IG/TR
IG and/or TR (see also IG, TR)
Ig
immunoglobulin (as part of a IG class name, e.g. IgM, or of a prefix Ig-like, IgSF), see also IG
IGH
IG heavy
IGHV
IG heavy variable
IGK
IG kappa
IGKV
IG kappa variable
IGL
IG lambda
IGLV
IG lambda variable
IgSF
immunoglobulin superfamily
IMGT
IMGT®, the international ImMunoGeneTics information system®
INN
International Nonproprietary Name (DCI in French)
J
joining
kb
kilobase (103 bases). Unit of length of nucleic acids (DNA or RNA). For double-stranded DNA, 103 base pairs (see also Mb, Gb)
kDa
kilodalton
LIGM-DB
Laboratoire d'ImmunoGénétique Moléculaire DataBase (Immunoglobulin and T cell receptor sequence database), part of IMGT
mAb
monoclonal antibody
Mb
megabase (106 bases; a million bases). Unit of length of nucleic acids. For double-stranded DNA, 106 base pairs (see also kb, Gb)
MHC
major histocompatibility complex
MhcSF
major histocompatibility complex superfamily
mIG
membrane IG (defined has having a transmembrane region TM, refers usually to IG on the B cell surface and part of the BcR). If needed, localization can be added: surface mIG for mIG on cell surface or ER mIG for mIG on endoplasmic reticulum membrane.
mIgM
membrane IgM (also for the other classes e.g. mIgD and subclasses e.g. mIgG3)
MMP
matrix metalloproteinase
MMR
DNA mismatch repair
Nb or nb
number
nm
nanometer (10-9 meter, 1 nm = 10 Å) (better to use nm rather than Å)
nt
nucleotide
OMIM
Online Mendelian Inheritance in Man (MIM)
OMS
Organisation mondiale de la Santé (WHO in English)
ORF
open reading frame
PB
peripheral blood
pMHC
peptide-MHC complex
PtC
phosphatidyl choline
r or R
purine (purine base of DNA, a or g, or A or G)
RA
rheumatoic arthritis
RBC
red blood cell
RF
rheumatoid factor
RPI
related proteins of the immune system
RS
recombination signal
S
switch
SE
shared epitope (refers for HLA-DRB1 to the RAA pattern at positions 68-70, according to the IMGT unique numbering for G-DOMAIN, but the use of SE for this pattern is inappropriate and not recommended)
SHM
somatic hypermutation
sIgM
secreted IgM
SLE
systemic lupus erythematosus
SRS
Sequence Retrieval System, a database query system developed by EMBL
ssDNA
single-stranded DNA
SSP-PCR
sequence specific primer polymerase chain reaction
t or T
thymine (pyrimidine base of DNA)
TAMRA
5-(or/and -6)-carboxytetramethylrhodamine
TcR
T cell receptor (on the surface of T cells, comprising one TR associated with the coreceptor CD3 proteins, CD3G, CD3D, CD3E, CD3Z, assembled in dimers)
TdT
terminal deoxynucleotidyl transferase
TM
TRANSMEMBRANE-REGION (IMGT label)
TR
T cell receptor (for locus, gene, chain or receptor)
TRA
TR alpha
TRAV
TR alpha variable
TRB
TR beta
TRBV
TR beta variable
TRG
TR gamma
TRGV
TR gamma variable
TRD
TR delta
TRDV
TR delta variable
UDG
uracil-DNA glycosylase
V
variable
w or W
a or t, or A or T, adenine or thymine
WHO
World Health Organization (OMS in French)
y or Y
pyrimidine (pyrimidine base of DNA, c or t, or C or T)
See also:
Created:
15/06/2001
Last updated:
Thursday, 17-Nov-2016 14:10:37 CET
Authors:
Elodie Foulquier and Marie-Paule Lefranc
Editor:
Chantal Ginestoux