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IMGT color menu

Colors are defined according to the RGB decimal or hexadecimal color chart.

Color menu for amino acids

Color menu for amino acids is according to [1]

  [230,6,6] [#E60606] R - Arg - Arginine
  [198,66,0] [#C64200] K - Lys - Lysine
  [255,102,0] [#FF6600] Q - Gln - Glutamine
  [255,153,0] [#FF9900] N - Asn - Asparagine
  [255,204,0] [#FFCC00] E - Glu - Glutamic Acid
  [255,204,153] [#FFCC99] D - Asp - Aspartic Acid
  [255,255,153] [#FFFF99] H - His - Histidine
  [255,255,0] [#FFFF00] P - Pro - Proline
  [204,255,204] [#CCFFCC] Y - Tyr - Tyrosine
  [204,153,255] [#CC99FF] W - Trp - Tryptophan
  [204,255,153] [#CCFF99] S - Ser - Serine
  [0,255,153] [#00FF99] T - Thr - Threonine
  [0,255,0] [#00FF00] G - Gly - Glycine
  [204,255,255] [#CCFFFF] A - Ala - Alanine
  [153,204,255] [#99CCFF] M - Met - Methionine
  [0,255,255] [#00FFFF] C - Cys - Cysteine
  [0,204,255] [#00CCFF] F - Phe - Phenylalanine
  [51,102,255] [#3366FF] L - Leu - Leucine
  [0,0,255] [#0000FF] V - Val - Valine
  [0,0,128] [#000080] I - Ile - Isoleucine

Color menu for the 11 IMGT amino acid Physicochemical classes

Color menu for the 11 IMGT amino acid Physicochemical classes is according to [2]

  [27,4,172] [#1B04AC] A,I,L,V- Aliphatic
  [255,255,0] [#FFFF00] P - Pro - Proline
  [204,255,204] [#CCFFCC] Y - Tyr - Tyrosine
  [204,153,255] [#CC99FF] W - Trp - Tryptophan
  [0,255,0] [#00FF00] G - Gly - Glycine
  [0,204,255] [#00CCFF] F - Phe - Phenylalanine
  [204,236,255] [#CCECFF] C,M - Sulfur
  [137,248,139] [#89F88B] S,T - Hydroxyl
  [255,204,0] [#FFCC00] D,E - Acidic
  [204,165,4] [#CCA504] N,Q - Amide
  [236,21,4] [#EC1504] R,H,K - Basic

Color menu for the 7 IMGT amino acid Chemical classes

If IMGT tools are limited to 7 choices of colors, the following menu is used.

  [27,4,172] [#1B04AC] A,I,L,V- Aliphatic
  [204,236,255] [#CCECFF] C,M - Sulfur
  [137,248,139] [#89F88B] S,T - Hydroxyl
  [255,204,0] [#FFCC00] D,E - Acidic
  [204,165,4] [#CCA504] N,Q - Amide
  [236,21,4] [#EC1504] R,H,K - Basic
  [204,153,255] [#CC99FF] F,W,Y - Aromatic

Color menu for the 5 IMGT amino acid Volume classes

Color menu for the 5 IMGT amino acid Volume classes is according to [2]

  [255,153,153] [#FF9999] [60-90[ (A,G,S)
  [230,6,6] [#E60606] [108-117[ (N,D,C,P,T)
  [255,255,0] [#FFFF00] [138-154[ (Q,E,H,V)
  [153,204,255] [#99CCFF] [162-174[ (R,I,L,K,M)
  [51,102,255] [#3366FF] [189-228[ (F,W,Y)

Color menu for the 3 IMGT amino acid Hydropathy classes

Color menu for the 3 IMGT amino acid Hydropathy classes is according to [2]

  [51,102,255] [#3366FF] A,C,I,L,M,F,W,V - Hydrophobic
  [255,255,0] [#FFFF00] G,H,P,S,T,Y - Neutral
  [230,6,6] [#E60606] R,N,D,Q,E,K - Hydrophilic

Color menu for the 3 IMGT amino acid Charge classes

Color menu for the 3 IMGT amino acid Charge classes is according to [2]

  [204,236,255] [#CCECFF] A,N,C,Q,G,I,L,M,F,P,S,T,W,Y,V - Uncharged
  [236,21,4] [#EC1504] R,H,K - Positive charged
  [255,204,0] [#FFCC00] D,E - Negative charged

Color menu for the 2 IMGT amino acid Polarity classes

Color menu for the 2 IMGT amino acid Polarity classes is according to [2]

  [230,6,6] [#E60606] R, N, D, Q, E, H, K, S, T, Y - Polar
  [51,102,255] [#3366FF] A, C, G, I, L, M, F, P, W, V - Nonpolar

Color menu for the 4 IMGT amino acid Hydrogen donor or acceptor atoms classes

Color menu for the 4 IMGT amino acid Hydrogen donor or acceptor atoms classes is according to [2]

  [0,204,255] [#00CCFF] R,K,W - Donor
  [255,255,0] [#FFFF00] D,E - Acceptor
  [137,248,139] [#89F88B] N,Q,H,S,T,Y - Donor and acceptor
  [211,211,211] [#D3D3D3] A,C,G,I,L,M,F,P,V - None

Color menu for nucleotides

  [0,204,0] [#00CC00] A
  [204,0,0] [#CC0000] T
  [255,179,0] [#FFB300] G
  [0,0,204] [#0000CC] C

Color menu for CDR-IMGT

IG heavy, TR beta, TR delta chains
  [200,0,0] [#C80000] CDR1-IMGT
  [255,169,0] [#FFA900] CDR2-IMGT
  [156,65,215] [#9C41D7] CDR3-IMGT
IG light, TR alpha, TR gamma chains
  [96,96,228] [#6060E4] CDR1-IMGT
  [70,213,0] [#46D500] CDR2-IMGT
  [63,157,63] [#3F9D3F] CDR3-IMGT

Color menu for genes

The color menu for genes is used in Locus representations.

  [0,238,0] [#00EE00] V-GENE Functionnal
  [255,255,0] [#FFFF00] V-GENE ORF
  [255,51,0] [#FF3300] V-GENE Pseudogene
  [169,169,169] [#A9A9A9] V-GENE Vestigial
  [0,0,228] [#0000E4] D-GENE Functionnal
  [0,0,228] [#0000E4] D-GENE ORF
  [128,0,128] [#800080] D-GENE Pseudogene
  [255,228,0] [#FFE400] J-GENE Functionnal
  [255,228,0] [#FFE400] J-GENE ORF
  [255,106,0] [#FF6A00] J-GENE Pseudogene
  [0,153,250] [#0099FA] C-GENE Functionnal
  [0,153,250] [#0099FA] C-GENE ORF
  [0,153,250] [#0099FA] C-GENE Pseudogene
[228,0,228] [#E400E4] Genes not related Functionnal
[228,0,228] [#E400E4] Genes not related Pseudogene
  [] [] Conventional VPREB and IGLL genes are represented using the same color menu as V-GENE and C-GENE, respectively.

Color menu for regions and domains

  [255,255,0] [#FFFF00] L-REGION
  [0,238,0] [#00EE00] V-REGION
  [255,51,0] [#FF3300] D-REGION, (N-D)-REGION
  [255,204,0] [#FFCC00] J-REGION
  [193,217,249] [#C1D9F9] C-DOMAIN
  [193,217,249] [#C1D9F9] C-REGION
  [193,217,249] [#C1D9F9] CH1
  [0,117,255] [#0075FF] HINGE-REGION
  [0,117,255] [#0075FF] H, H1, H2, H3, H4, H5
  [224,242,245] [#E0F2F5] CH2
  [193,217,249] [#C1D9F9] CH3, CH5, CH7
  [224,242,245] [#E0F2F5] CH4, CH6
  [0,153,0] [#009900] CHS
  [193,217,249] [#C1D9F9] CL
  [254,234,200] [#FEEAC8] G-DOMAIN
  [254,234,200] [#FEEAC8] G-ALPHA, G-ALPHA1, G-ALPHA2, G-BETA
  [161,238,161] [#A1EEA1] V-LIKE-DOMAIN
[190,228,234] [#BEE4EA] C-LIKE-DOMAIN
  [254,234,200] [#FEEAC8] G-LIKE-DOMAIN, G-ALPHA1-LIKE, G-ALPHA2-LIKE
  [255,204,150] [#FFCC96] CONNECTING-REGION
  [212,202,217] [#D4CAD9] TRANSMEMBRANE-REGION
  [255,204,204] [#FFCCCC] CYTOPLASMIC-REGION
  [255,255,223] [#FFFFDF] FIBRONECTIN-DOMAIN

Color menu for mutations

Color menu for mutations is according to Rules for description of genes and alleles in IMGT Repertoire (IMGT annotation rules)

n [255,0,0] [#FF0000] nucleotide mutations and amino acid changes for a given codon
n [0,0,0] [#000000] nucleotide mutations and amino acid changes at the 3' end of V-REGION, 5' end of J-REGION, or on either end of D-REGION, which may belong to the N-REGION

Color menu for sequence alignments

The color menu for sequence alignments is used in:

  [255,204,150] [#FFCC96] CONNECTING-REGION
  [212,202,217] [#D4CAD9] TRANSMEMBRANE-REGION
  [255,204,204] [#FFCCCC] CYTOPLASMIC-REGION
BC [128,0,0] [#800000] BC, C' and C'' loops in V-REGION, BC and FG loops in C-REGION
AB [0,0,0] [#000000] AB, CD, DE and EF turns in C-REGION
C [204,51,204] [#CC33CC] 1st-CYS and 2nd-CYS (intrachain disulfide bridge)
W [0,0,255] [#0000FF] CONSERVED-TRP
L [51,102,255] [#3366FF] conserved hydrophobic amino acids (A, C, F, I, L, M, V, W)
N [0,255,0] [#00FF00] N (Asn, asparagine) is potential N-glycosylation site that belong to the N-glycosylation motif NXS/T, where X is any amino acid except proline (P)
M [255,0,0] [#FF0000] INIT-CODON (atg)
* [255,0,0] [#FF0000] STOP-CODON (taa, tga, tag)

Color menu for splicing types

Color menu for splicing types identify the nucleotides and amino acids resulting from the splicing (splicing frames 1 and 2) or next to the splicing (splicing frame 0).

The last nucleotide of the upstream 5' exon is shown in bold and is colored in purple (splicing frame 1), green (splicing frame 2) or blue (splicing frame 0).
The first amino acid the downstream (3') exon is in bold and is colored in purple (splicing frame 1), green (splicing frame 2) or blue (splicing frame 0).
For the splicing frames 1 and 2, that amino acid results from the splicing.

Each splicing type is illustrated with an example, below.

Splicing frame 0 (codon_start1)
Splicing frame 0 (codon_start1)
N [50,50,205] [#3232CD] codon_start1
  [255,204,204] [#FFCCCC] INTRACYTOPLAMIC-REGION
Splicing frame 1 (codon_start3)
Splicing frame 1 (codon_start3)
G [204,51,204] [#CC33CC] codon_start3
  [255,255,0] [#FFFF00] L-REGION
Splicing frame 2 (codon_start2)
Splicing frame 2 (codon_start2)
S [0,255,0] [#00FF00] codon_start2
  [255,204,150] [#FFCC96] CONNECTING-REGION

Color menu for splicing representation

Spliced intron
  [204,51,204] [#CC33CC] Splicing frame 1
  [0,255,0] [#00FF00] Splicing frame 2
  [50,50,205] [#3232CD] Splicing frame 0
Exon or intron not included in transcript
  [103,103,103] [#676767]  
Exon or intron modified length due to an alternative splicing
  [255,10,22] [#FF0A16]

Color menu for IMGT pMH contact sites

Color menu for IMGT pMH contact sites is according to [3]

  [255,0,0] [#FF0000] C1
  [128,128,128] [#808080] C2
  [0,0,255] [#0000FF] C3
  [0,255,0] [#00FF00] C4
  [0,128,255] [#0080FF] C5
  [255,255,0] [#FFFF00] C6
  [153,255,51] [#99FF33] C7
  [0,255,255] [#00FFFF] C8
  [128,128,255] [#8080FF] C9
  [255,179,0] [#FFB300] C10
  [255,128,255] [#FF80FF] C11

References:

  1. [1] Ruiz, M. and Lefranc, M.-P., Currents in Computational Molecular Biology, Frontiers Science Series n°30, Universal Academy Press, Tokyo, pp 126-127 (2000).
  2. [2] Pommié, C., Levadoux, S., Sabatier, R., Lefranc, G. and Lefranc, M.-P. "IMGT standardized criteria for statistical analysis of immunoglobulin V-REGION amino acid properties". Journal of Molecular Recognition, 17, 17-32 (2004) PMID: 14872534 LIGM:284 pdf
  3. [3] Kaas, Q. and Lefranc, M.-P. "T cell receptor/peptide/MHC molecular characterization and standardized pMHC contact sites in IMGT/3Dstructure-DB". In Silico Biology, 2005, 5, 505-528. Epub 2005, 5, 0046, Oct 20. PMID: 16268793 LIGM:306 pdf
See also:
Created:
19/04/2001
Last updated:
Friday, 27-May-2016 21:00:51 CEST
Authors:
Elodie Foulquier, Chantal Ginestoux
Editor:
Chantal Ginestoux
Scientific officer:
Marie-Paule Lefranc