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QUESTION 6:

Are all the human TRD genes known?
How to analyse the expressed variable TRD genes?


ANSWER to question 6:

All the human TRD genes are known and well characterized. The human TRD genes were approved by the HUGO Nomenclature committee in 1999 (http://www.hugo-international.org/) and entered in the Genome Database GDB, Canada (http://www.ncbi.nlm.nih.gov/sites/genome) and into Entrez Gene (http://www.ncbi.nlm.nih.gov/gene) at NCBI, USA.
A complete list is available in the IMGT Repertoire.

IMGT/GENE-DB an IMGT database for the human IG and TR genes

IMGT/V-QUEST, an IMGT tool for the analysis of the Variable genes, provides:

    1) the identification of the TRDV, TRDD and TRDJ genes involved in the rearrangements,
    2) the characterization of the V-D-J-JUNCTION,
    3) the 2D representation or Collier de Perles.


Created: 11/06/2001
Last updated: 06/06/2016
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Editor: Elodie Foulquier

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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