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Molekulargenetik des Immunglobulins

Abbildung 1 Modell eines Immunglobulins.
Abbildung 2 Schema der Synthese der "leichten" Kappa-Kette.
Abbildung 3 Schematische Darstellung der Rekombinationssignale der Gene V, J des Genlokus IGK, IGL und der Gene V, D und J des Genlokus IGH.
Abbildung 4 Schema der Synthese der "schweren" Mü-Kette.
Abbildung 5 Schema der Differenzierung der B-Lymphozyten.
Abbildung 6 Schema des Klassenwechsels von IgM zu IgG: Rekombination von Smü und Sgamma.
Abbildung 7 Schema der Synthese der membranären und der sekretierten Mü-Kette.
Abbildung 8 Rekombination der Gene IGH und IGK in Pro- und Prä- B-Lymphozyten.


Created: 08/10/2003
Last upadted: Wednesday, 29-Jun-2011 17:01:51 CEST
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Translator: Oliver Pohl
Editors: Céline Protat

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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