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Régulation de la transcription des gènes des immunoglobulines

Figure 1: Structure consensus des extrémités 5' des gènes V d'immunoglobulines.
Figure 2: Séquences conservées des promoteurs des gènes IGHV.
Figure 3: Localisation du domaine POU dans les quatre protéines Oct-1, Oct-2, unc-86 et Pit-1.
Figure 4: Localisation des deux activateurs IGK E5' et E3'.
Figure 5: Organisation de l'activateur IGK E5' localisé entre IGKJ5 et IGKC.
Figure 6: Délétion de l'activateur IGK E3' lors de la recombinaison de l'élément RS chez la souris (ou Kde chez l'homme)
Figure 7: Organisation de l'activateur IGH E5' localisé entre le gène IGHJ le plus en 3' et IGHM.


Created: 28/06/2001
Last upadted: Wednesday, 29-Jun-2011 17:01:42 CEST
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Editors: Elodie Foulquier, Chantal Ginestoux

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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