The 'interaction' concept is part of IMGT-ONTOLOGY.
The 'interaction' concept comprises the concepts of interaction that are necessary to define interactions between components at the molecule, cell, organ, organism and/or populaton level.
At the molecular level, major concepts of interaction were generated, based on the standardized concepts of classification, description and numerotation, for example:
- the 'pMHC contact site' concept
- the 'IMGT Residue@Position' concept.
The 'pMHC contact site' concept allows to define peptide/MHC interactions, whereas the 'IMGT Residue@Position' concept allows to define antigen/receptor and domain interactions.
 Kaas, Q. and Lefranc, M.-P. "T cell receptor/peptide/MHC molecular characterization and standardized pMHC contact sites in IMGT/3Dstructure-DB" In Silico Biology. Epub 2005, 5, 0046 Oct 20, 5, 505-528 (2005). PMID: 16268793
 Kaas, Q., Duprat, E., Tourneur, G. and Lefranc, M.-P. "IMGT standardization for molecular characterization of the T cell receptor/peptide/MHC complexes" In: Immunoinformatics (Schoenbach C., Ranganathan S. and Brusic V. eds.), Immunomics Reviews, Series of Springer Science and Business Media LLC, Springer, New York, USA chap. 2, pp.19-49 (2008)