IMGT®, the international ImMunoGeneTics information system®

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Data coherence

Data coherence in IMGT combines data integrity control and biological data evaluation [1].

Data integrity control

An administration system has been set up to coordinate the entry flow [1]. This ensures coherence of the IMGT data which come from multiple sources: core data from EMBL, annotations from LIGM experts, and annotations from direct submissions by the authors.

Biological data evaluation

Prototypes have been constructed to represent the organizational relationship between labels [1-4] for each configuration of Ig or TcR, independently of the chain type, the species or any other parameters like functionality. Knowledge tables have been built to record controled vocabulary and rules [1-5] defined in the IMGT Scientific chart.

Knowledge tables allow:

[1] Giudicelli, V., et al., Proceedings of the Sixth International Conference on Intelligent Systems for Molecular Biology, ISBM-98, 59-68 (1998) PMID: 9783210.
[2] Giudicelli, V. and Lefranc, M.-P., Bioinformatics, 15, 1047-1054 (1999) PMID: 10745995, LIGM:221 pdf
[3] Guidicelli, V. et al., Nucleic Acids Res., 25, 206-211 (1997) PMID: 9016537, LIGM:186.
[4] Guidicelli, V. Ph D thesis, Université Montpellier II (11 December 1998) Conception d'une ontologie en Immunogénétique et développement d'un module de cohérence pour le contrôle de qualité de IMGT/LIGM-DB.
[5] Guidicelli, V. et al., MEDINFO 98, B Cesnik et al (Eds), Amsterdam, IOS Press, 351-355 (1998).