IMGT®, the international ImMunoGeneTics information system®

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Nomenclature

IMGT nomenclature has for objective to provide immunologists and geneticists with a unique nomenclature per locus which will allow extraction and comparison of data for the complex B and T cell antigen receptor molecules, whatever the species.

The WHO-IUIS Nomenclature Subcommitte for Immunoglobulins and T cell receptors report. Aug. 19, 2007. pdf [16,17]

Exhaustive and standardized list of human IG and TR gene names and mouse IG and TR gene names are available from the IMGT Repertoire at the IMGT Web resources [6]. These lists provide links to NCBI (for human), MGD (for mouse), and Entrez Gene entries.

IMGT/GENE-DB allows to retrieve information on human and mouse IG and TR genes based on the IMGT gene name nomenclature [15].

The nomenclature of IG and TR genes and alleles has been approved by the WHO-IUIS Nomenclature Subcommittee/IMGT Nomenclature (IMGT-NC) Subcommittee for immunoglobulins and T cell receptors [16,17].

References:
[1] Giudicelli, V. and Lefranc, M-P., Bioinformatics, 15, 1047-1054 (1999) PMID: 10745995, LIGM:221 pdf
[2] Ghanem, N. et al., Exp. Clin. Immunogenet., 5, 186-195 (1988) PMID: 2908491, LIGM:63
[3] Bensmana, M. et al., Nucleic Acids Res., 16, 3108 (1988) PMID: 3130612, LIGM:65
[4] Lefranc, M.-P. and Rabbitts, T.H., Trends Biochem. Sci., 14, 214-218 (1989) PMID: 2527426, LIGM:84
[5] Lefranc, M.-P. and Rabbitts, T.H., Res. Immunol., 141, 615-618 (1990) PMID: 2151348, LIGM:126
[6] Lefranc, M.-P., Current Protocols in Immunology, Wiley, J. and Sons, New York, Supplement 40, A.1P.1-A1P.37 (2000), LIGM:230 PMID: 10087405, LIGM:210 pdf
[7]Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, 458 pages (2001) ISBN: 012441351X
[8] Lefranc, M.-P., Exp. Clin. Immunogenet., 18, 100-116 (2001) PMID: 11340299, LIGM:246 pdf
[9] Lefranc, M.-P., Exp. Clin. Immunogenet., 18, 161-174 (2001) PMID: 11549845, LIGM:251 pdf
[10] Lefranc, M.-P., Exp. Clin. Immunogenet., 18, 242-254 (2001) PMID: 11872955, LIGM:254 pdf
[11] Lefranc, M.-P., Current Protocols in Immunology, Wiley, J. and Sons, New York, Supplement 40, A.1O.1-A.1O.23 (2000) LIGM:231
[12] Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, 398 pages (2001) ISBN: 0124413528
[13] Wain, H.M. et al., Genomics, 79, 464-470 (2002) PMID: 11944974
[14] Glusman, G. et al., Immunity, 15, 337-349 (2001) PMID: 11567625
[15] Giudicelli, V. et al., Nucl. Acids Res., D593-D597 (2005) PMID: 15608269
[16] WHO-IUIS Nomenclature Subcommittee for immunoglobulins and T cell receptors report - Aug. 2007, Dev. Comp. Immunol., 2007 Nov 6 (2007) PMID: 18036660
[17] WHO-IUIS Nomenclature Subcommittee for immunoglobulins and T cell receptors report - Nov. 2007, Immunogenetics, 59, 899-902 (2007) PMID: 18046549