3D representation: Mouse (Mus musculus) two associated V-DOMAINs from D1.3Fv (PDB: 1dvf_A and 1dvf_B)

IMGT/3Dstructure-DB card: 1dvf

Colliers de Perles: IGH V-D-J-REGION
Colliers de Perles: IGK V-J-REGION

Side view (backbone model)

V-DOMAIN
VH
IGH
V-D-J-REGION
(PDB: 1dvf_B)
V-DOMAIN
V-KAPPA
IGK
V-J-REGION
(PDB: 1dvf_A)

A V-DOMAIN corresponds to the V-J-REGION or V-D-J-REGION of the immunoglobulin and T cell receptor chains.
This figure shows the two associated V-DOMAINs isolated from an antibody and constituting what is called a "Fv" (for "fragment variable")

Legend:

See also:
  • DOMAIN in IMGT Index
  • IMGT 2D and 3D representations (examples) in IMGT Repertoire.


    Created: 11/06/2001
    Last updated: Friday, 27-May-2016 21:01:21 CEST
    Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
    Editor: Elodie Foulquier

    Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
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