FR-IMGT and CDR-IMGT lengths: Mouse ( Mus musculus) TRAV

TRAV genes are designated according to IMGT gene tables and Locus representations.

Only FUNCTIONAL and ORF V-GENEs are shown.

The proteolytic cleavage site between the leader peptide and the V-REGION is putative and the assignment of amino acid 1 to one or the other region is uncertain.

In this Mouse (Mus musculus) TRAV Table of FR-IMGT and CDR-IMGT length, are reported the 10 TRAV/DV genes identified so far:
- Eight TRAV/DV genes (TRAV4-4/DV10, TRAV6-7/DV9, TRAV13-4/DV7, TRAV14D-3/DV8, TRAV15D-1/DV6D-1, TRAV15-1/DV6-1, TRAV16D/DV11 and TRAV21/DV12) which have been found rearranged to TRAJ genes and to (D)J-GENEs of the TRD locus.
- TRAV15-2/DV6-2 and TRAV15D-2/DV6D-2, which are assigned to the TRAV15 subgroup on the basis of sequence alignment, although they have not yet been found rearranged to TRAJ genes.

TRAV
genes
(1)
FR1-IMGT
1 to 26
CDR1-IMGT
27 to 38
FR2-IMGT
39 to 55
CDR2-IMGT
56 to 65
FR3-IMGT
66 to 104
CDR3-IMGT
(germline V-GENE)
105 to 115
(25,26) (5 to 8) (17) (3 to 7) (35 to 36) (3 to 5)
TRAV1 -1 (aa 7) 6   5 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV2 -1 (aa 7) 7   4 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 4
TRAV3-1
TRAV3-3
TRAV3D-3
TRAV3-4
  6   6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV4-2
TRAV4-3
TRAV4D-3
TRAV4-4/DV10
TRAV4D-4
  5   4 -7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +4 (aa 84A,84B,84C,84D)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
3
TRAV5-1
TRAV5-4
TRAV5D-4
 
6
 
6
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
3
TRAV6-1
TRAV6-2
TRAV6-3
TRAV6D-3
TRAV6-4
TRAV6D-4
TRAV6-5
TRAV6D-5
TRAV6-6
TRAV6D-6
TRAV6-7/DV9
TRAV6D-7
  6
6
6
6
6
6
6
6
8
8
6
6
  6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV7-1
TRAV7-2
TRAV7D-2
TRAV7-3
TRAV7D-3
TRAV7-4
TRAV7D-4
TRAV7-5
TRAV7D-5
TRAV7-6
TRAV7D-6
  6   5 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
3
3
3
3
4
4
3
3
3
3
TRAV8-1
TRAV8D-1
TRAV8-2
TRAV8D-2
 
5
 
6
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
3
TRAV9-1
TRAV9D-1
TRAV9-2
TRAV9D-2
TRAV9-3
TRAV9D-3
TRAV9-4
TRAV9D-4
  6   7 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV10
TRAV10D
  6   6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV11
TRAV11D
  6   6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV12-1
TRAV12D-1
TRAV12-2
TRAV12D-2
TRAV12-3
TRAV12D-3
  7
7
6
6
7
7
  6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 4
TRAV13-1
TRAV13D-1
TRAV13-2
TRAV13D-2
TRAV13-3
TRAV13D-3
TRAV13-4/DV7
TRAV13D-4
TRAV13-5
  5   4
4
4
4
5
5
4
4
3
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
-7 (aa 71 to 77) +3 (aa 84A,84B,84C)
3
TRAV14-1
TRAV14D-1
TRAV14-2
TRAV14D-2
TRAV14-3
TRAV14D-3/DV8
  6   6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV15-1/DV6-1
TRAV15D-1/DV6D-1
TRAV15-2/DV6-2
TRAV15D-2/DV6D-2
  7   7 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 5
TRAV16
TRAV16D/DV11
  7   7 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 4
TRAV17   6   7 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV18   5   6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 2
TRAV19   6   6 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 3
TRAV21/DV12   7   4 -7 (aa 71 to 77) +3 (aa 84A,84B,84C) 4

IMGT Note:
(1) The TRAV3-2, TRAV3D-2, TRAV4-1, TRAV4-2, TRAV5-2, TRAV5D-2, TRAV5-3, TRAV5D-3, TRAV12-4, TRAV15-3, TRAV15D-3, TRAV20, TRAV22 and TRAV23 genes are not shown, being pseudogenes due to frameshift or STOP-CODONs in the V-REGIONs.


Created: 11/04/2001
Last updated: Friday, 27-May-2016 21:01:33 CEST
Author: Nathalie Bosc

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