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IG groups: Human

IMGT groups and links with HGNC, NCBI Gene and OMIM

There are 10 IMGT groups for the human immunoglobulin (IG) genes:

Portail to the Gene tables

Click on the 'IMGT group name' for the corresponding Gene tables.

IMGT group name IMGT group definition HGNC NCBI Gene OMIM
IGHC Immunoglobulin heavy constant group - - - (2-3)
IGHD Immunoglobulin heavy diversity group IGHD 50648 146910
IGHJ Immunoglobulin heavy joining group IGHJ 3506 147010
IGHV Immunoglobulin heavy variable group IGHV 3509 147070
IGKC (1) Immunoglobulin kappa constant group (1) - - - (3)
IGKJ Immunoglobulin kappa joining group IGKJ 7842 146970
IGKV Immunoglobulin kappa variable group IGKV 3519 146980
IGLC Immunoglobulin lambda constant group IGLC 3536 147220
IGLJ Immunoglobulin lambda joining group IGLJ 8217 147230
IGLV Immunoglobulin lambda variable group IGLV 3546 147240

 

IMGT gene
designation
IMGT definition OMIM Other related OMIM entries
on regulation on diseases
IGHA1 Immunoglobulin heavy constant alpha 1 gene 146900 137050
144120
137100
161950
IGHA2 Immunoglobulin heavy constant alpha 2 gene (A2m marker) 147000
IGHD Immunoglobulin heavy constant delta gene 147170 242890
IGHE Immunoglobulin heavy constant epsilon gene 147180 147061
IGHG1 Immunoglobulin heavy constant gamma 1 gene (G1m marker) 147100 144120
IGHG2 Immunoglobulin heavy constant gamma 2 gene (G2m marker) 147110
IGHG3 Immunoglobulin heavy constant gamma 3 gene (G3m marker) 147120
IGHG4 Immunoglobulin heavy constant gamma 4 gene (G4m marker) 147130
IGHGP Immunoglobulin heavy constant gamma P gene -
IGHM Immunoglobulin heavy constant mu gene 147020 308250 180330
308230
IGKC Immunoglobulin kappa constant gene 147200
IMGT notes:
(1) Group containing a single gene.
(2) There is no IGHC group entry in OMIM but an entry for each of the 9 functional IGHC genes.
(3) Gene entries in OMIM: There are 10 individual IG gene entries in OMIM, 9 for the IGH locus and 1 for the IGK locus.
Links between IMGT, NCBI Gene and OMIM for the genes shown in this table are available in the Lists of human IG and TR genes, groups, loci and orphons.
Reference:
[1] Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, 458 pages (2001) ISBN: 012441351X.
See also:
Created:
20/01/2001
Last updated:
Tuesday, 07-Jun-2016 21:02:55 CEST
Authors:
Véronique Giudicelli and Marie-Paule Lefranc
Editors:
Elodie Foulquier, Chantal Ginestoux