Print of this table: Folch, G. and Lefranc, M.-P., Exp. Clin. Immunogenet., 17, 42-54 (2000). PMID:10686482

• 64-67 TRBV genes belonging to 30 subgroups, on 620 kilobases :
  • 40-42 FUNCTIONAL
  • 6 ORF (Open Reading Frame)
  • 12-13 PSEUDOGENE
  • 5 FUNCTIONAL or PSEUDOGENE
  • 1 FUNCTIONAL or ORF

• Potential repertoire : 40-48 FUNCTIONAL TRBV genes belonging to 21-23 subgroups

IMGT TRBV subgroups are according to Rowen, L. et al., Science, 272, 1755-1762 (1996).
For correspondence between nomenclatures, click here

Subgroup	Functional	ORF	Pseudogene	Total
TRBV1	-	-	1	1
TRBV2	1	-	-	1
TRBV3	1	-	0-1**	1-2**
TRBV4	2-3**	-	-	2-3**
TRBV5	5	2	1	8
TRBV6	6-7**(+1)*	1	(1)*	8-9**
TRBV7	5(+2)*	1(+1)*	1(+1)*	9
TRBV8	-	-	2	2
TRBV9	1	-	-	1
TRBV10	2(+1)*	-	(1)*	3
TRBV11	3	-	-	3
TRBV12	3	-	2	5
TRBV13	1	-	-	1
TRBV14	1	-	-	1
TRBV15	1	-	-	1
TRBV16	(1)*	-	(1)*	1
TRBV17	-	1	-	1
TRBV18	1	-	-	1
TRBV19	1	-	-	1
TRBV20	1	-	-	1
TRBV21	-	-	1	1
TRBV22	-	-	1	1
TRBV23	-	1	-	1
TRBV24	1	-	-	1
TRBV25	1	-	-	1
TRBV26	-	-	1	1
TRBV27	1	-	-	1
TRBV28	1	-	-	1
TRBV29	1	-	-	1
TRBV30	(1)*	-	(1)*	1
TRBVA	-	-	1	1
TRBVB	-	-	1	1
Total	40-42(+6)*	6(+1)*	12-13(+5)*	64-67

* FUNCTIONAL or PSEUDOGENE (TRBV6-2, TRBV7-4, TRBV10-1, TRBV16, TRBV30)
* FUNCTIONAL or ORF (TRBV7-3)
** Allelic polymorphism by insertion/deletion (TRBV3-2, TRBV4-3, TRBV6-3)

Created: 09/04/1997
Last updated: Friday, 29-Jul-2011 22:30:31 CEST
Author: Géraldine Folch

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