References:
Lefranc M.-P. et al., Eur. J. Immunol., 19, 989-994 (1989), PMID:2526744 |
Zhang X.M. et al. Eur.J.Immunol., 24, 571-578 (1994), PMID:8125127 |
TRGV Subgroup |
TRGV gene name |
Functional | ORF | Pseudogene | Total |
1 | TRGV1 | - | 1 | - | 1 |
TRGV2 | 1 | - | - | 1 | |
TRGV3 | 1 | - | - | 1 | |
TRGV3P | 0-1** | ||||
TRGV4 | 0-1** | - | - | 0-1** | |
TRGV5 | 0-1** | - | - | 0-1** | |
TRGV5P | - | - | 1 | 1 | |
TRGV6 | - | - | 1 | 1 | |
TRGV7 | - | - | 1 | 1 | |
TRGV8 | 1 | - | - | 1 | |
2 | TRGV9 | 1 | - | - | 1 |
3 | TRGV10 | - | 1 | - | 1 |
4 | TRGV11 | - | 1 | - | 1 |
A | TRGVA | - | - | 1 | 1 |
B | TRGVB | - | - | 1 | 1 |
Total | 4-6 | 3 | 5 | 12-15 |
** Allelic polymorphism by insertion/deletion. The TRGV3P gene, a polymorphic
gene by insertion, has been identified by Southern hybridization in a rare
haplotype but has not been sequenced (Ghanem N. et al., Hum. Genet., 86, 450-456 (1991),
PMID:1673112).
The most frequent haplotype comprises 14 TRGV genes (6 FUNCTIONAL + 3 ORF + 5 PSEUDOGENE)
with V4 and V5 present, and V3P absent.
Created: 09/04/1997
Last updated: 29/06/2011
Authors: Marie-Paule Lefranc, Géraldine Folch
Software material and data coming from IMGT server may be used for academic research only,
provided that it is referred to IMGT®, and cited as
"IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org
(founder and director: Marie-Paule Lefranc, Montpellier, France)."
References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209
Full text
Cover;
Ruiz, M. et al.,
Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085
Full text;
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056
Full text.
For any other use please contact Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr.
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