Number of germline genes and potential repertoire: Mouse (Mus musculus) TRAV on chromosome 14 at position 19.7 cM

Print of this table: Bosc, N. and Lefranc, M.-P., Dev. Comp. Immunol., 27, 465-497 (2003). PMID:12697305
UPDATE: 30/04/2003

For Number of germline genes and potential repertoire: Mouse (Mus musculus) TRDV, click here

For Correspondence between the different gene nomenclatures: Mouse (Mus musculus) TRAV, click here

Subgroup (1) Functional ORF Pseudogene Total
TRAV1 1 - - 1
TRAV2 1 - - 1
TRAV3 4 - 2 6
TRAV4/DV10 (2) 5 - 2 7
TRAV5 1(+1)* 1(+1)* 4 7
TRAV6/DV9 (3) 11(+1)* - (1)* 12
TRAV7 11 - - 11
TRAV8 4 - - 4
TRAV9 7(+1)* - (1)* 8
TRAV10 (2)* - (2)* 2
TRAV11 1(+1)* - (1)* 2
TRAV12 4(+2)* (2)* 1 7
TRAV13/DV7 (4) 8(+1)* (1)* - 9
TRAV14/DV8 (5) 5(+1)* (1)* - 6
TRAV15/DV6 (6) 4 - 2 6
TRAV16/DV11 (7) 2 - - 2
TRAV17 1 - - 1
TRAV18 - 1 - 1
TRAV19 (1)* - (1)* 1
TRAV20 - - 1 1
TRAV21/DV12 (8) 1 - - 1
TRAV22 - - 1 1
TRAV23 - - 1 1
Total 71(+11)* 2(+5)* 14(+6)* 98

* FUNCTIONAL or ORF (TRAV5-4, TRAV5D-4, TRAV12D-3, TRAV13-3, TRAV14D-1)
* FUNCTIONAL or PSEUDOGENE (TRAV6-7, TRAV9D-2, TRAV10, TRAV10D, TRAV11, TRAV19)

IMGT notes:
(1)The 7 TRAV subgroups in which at least one gene has been found rearranged to TRDD genes are shown with their TRDV subgroup assignment.
(2)Only the TRAV4-4 gene of the TRAV4 subgroup has been found rearranged to TRDD genes.
(3)Only the TRAV6-7 gene of the TRAV6 subgroup has been found rearranged to TRDD genes.
(4)Only the TRAV13-4 gene of the TRAV13 subgroup has been found rearranged to TRDD genes.
(5)Only the TRAV14D-3 gene of the TRAV14 subgroup has been found rearranged to TRDD genes.
(6)Among the 4 functional genes of the TRAV15/DV6 subgroup, TRAV15-2/DV6-2 and TRAV15D-2/DV6D-2, have been assigned to this subgroup on the basis of sequence alignment, although they have so far been found only rearranged to TRDD genes and not to TRAJ genes (Bosc, N., IMGT comment, 01/08/2002).
(7)Only the TRAV16D gene of the TRAV16 subgroup has been found rearranged to TRDD genes.
(8)The TRAV21 gene, unique member of the TRAV21/DV12 subgroup has been found rearranged to TRDD genes.


Created: 10/04/2001
Last updated: Friday, 29-Jul-2011 22:30:31 CEST
Author: Nathalie Bosc

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