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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                     
                                     
                                      1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                      Q   V   Q   L   Q   Q   W   G   A       G   L   L   K   P   S   E   T   L   S 
  AB019439 IGHV4-34*01 F             cag gtg cag cta cag cag tgg ggc gca ... gga ctg ttg aag cct tcg gag acc ctg tcc
                                                                                                                    
  X92278   IGHV4-34*01 F VH5         --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  L10090   IGHV4-34*01 F 4d76        --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  Z12363   IGHV4-34*01 F DP-63       --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X56364   IGHV4-34*01 F VH4.21      --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  Z75354   IGHV4-34*01 F VH4-GL20    
                                                                                                                    
  M99684   IGHV4-34*02 F V4-34       --- --- --- --- --a --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92255   IGHV4-34*03 F VH4-MC5     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92257   IGHV4-34*03 F VH4-MC5b    --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92236   IGHV4-34*04 F 4.44        --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92237   IGHV4-34*05 F 4-44.3      --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92256   IGHV4-34*06 F VH4-MC5a    --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92258   IGHV4-34*07 F VH4-MC5c    --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  M95113   IGHV4-34*08 F H3          --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                          E   S       P               V               Q             
  Z14241   IGHV4-34*09 F 4.36        --- --- --- --g --- g-- -c- --- c-- ... --- --- g-- --- --- --a c-- --- --- ---
                                                          E   S       P               V                             
  Z14242   IGHV4-34*10 F 4.37        --- --- --- --g --- g-- -c- --- c-- ... --- --- g-- --- --- --- --- --- --- ---
                                                                                                                    
  X05716   IGHV4-34*11 F V58         --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X56591   IGHV4-34*12 F TouVH4.21   --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  Z75356   IGHV4-34*13 F VH4-GL4     


                                                             ___________________CDR1-IMGT____________________        
                                     
                                      21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                      L   T   C   A   V   Y   G   G   S   F                   S   G   Y   Y   W   S 
  AB019439 IGHV4-34*01 F             ctc acc tgc gct gtc tat ggt ggg tcc ttc ... ... ... ... agt ggt tac tac tgg agc
                                                                                                                    
  X92278   IGHV4-34*01 F VH5         --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  L10090   IGHV4-34*01 F 4d76        --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  Z12363   IGHV4-34*01 F DP-63       --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  X56364   IGHV4-34*01 F VH4.21      --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  Z75354   IGHV4-34*01 F VH4-GL20                        --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  M99684   IGHV4-34*02 F V4-34       --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  X92255   IGHV4-34*03 F VH4-MC5     --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  X92257   IGHV4-34*03 F VH4-MC5b    --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  X92236   IGHV4-34*04 F 4.44        --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                  C 
  X92237   IGHV4-34*05 F 4-44.3      --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- t--
                                                                                                                    
  X92256   IGHV4-34*06 F VH4-MC5a    --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  X92258   IGHV4-34*07 F VH4-MC5c    --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                      T                                             
  M95113   IGHV4-34*08 F H3          --- --- --- --- --- --- --- --- a-- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  Z14241   IGHV4-34*09 F 4.36        --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  Z14242   IGHV4-34*10 F 4.37        --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                          V                                         
  X05716   IGHV4-34*11 F V58         --- --- --- --- --- --- --- --- --- g-- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  X56591   IGHV4-34*12 F TouVH4.21   --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
                                                                                                                    
  Z75356   IGHV4-34*13 F VH4-GL4                         --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---


                                                                                                 _______________CDR2-
                                     
                                      41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                      W   I   R   Q   P   P   G   K   G   L   E   W   I   G   E   I   N   H   S     
  AB019439 IGHV4-34*01 F             tgg atc cgc cag ccc cca ggg aag ggg ctg gag tgg att ggg gaa atc aat cat agt ...
                                                                                                                    
  X92278   IGHV4-34*01 F VH5         --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  L10090   IGHV4-34*01 F 4d76        --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  Z12363   IGHV4-34*01 F DP-63       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  X56364   IGHV4-34*01 F VH4.21      --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  Z75354   IGHV4-34*01 F VH4-GL20    --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  M99684   IGHV4-34*02 F V4-34       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  X92255   IGHV4-34*03 F VH4-MC5     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  X92257   IGHV4-34*03 F VH4-MC5b    --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  X92236   IGHV4-34*04 F 4.44        --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                          L                                                         
  X92237   IGHV4-34*05 F 4-44.3      --- --- --- --- --- -t- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  X92256   IGHV4-34*06 F VH4-MC5a    --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  X92258   IGHV4-34*07 F VH4-MC5c    --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --c --- --- ...
                                                                                                                    
  M95113   IGHV4-34*08 F H3          --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  Z14241   IGHV4-34*09 F 4.36        --- --- --- --- --- --- --- --- --a --- --- --- --- --- --- --- --- --- --- ...
                                                                                                                    
  Z14242   IGHV4-34*10 F 4.37        --- --- --- --- --- --- --- --- --a --- --- --- --- --- --- --- --- --- --- ...
                                                                                              Y       Y   Y         
  X05716   IGHV4-34*11 F V58         --- --- --g --- --- --- --- --- --- --- --- --- --- --- t-t --- t-- t-- --- ...
                                                                                                      I             
  X56591   IGHV4-34*12 F TouVH4.21   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -t- --- --- ...
                                                                                                                    
  Z75356   IGHV4-34*13 F VH4-GL4     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                     IMGT________________                                                            
                                     
                                      61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                              G   S   T   N   Y   N   P   S   L   K       S   R   V   T   I   S   V 
  AB019439 IGHV4-34*01 F             ... ... gga agc acc aac tac aac ccg tcc ctc aag ... agt cga gtc acc ata tca gta
                                                                                                                    
  X92278   IGHV4-34*01 F VH5         ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  L10090   IGHV4-34*01 F 4d76        ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  Z12363   IGHV4-34*01 F DP-63       ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  X56364   IGHV4-34*01 F VH4.21      ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  Z75354   IGHV4-34*01 F VH4-GL20    ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  M99684   IGHV4-34*02 F V4-34       ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  X92255   IGHV4-34*03 F VH4-MC5     ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  X92257   IGHV4-34*03 F VH4-MC5b    ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                              N                                   A                 
  X92236   IGHV4-34*04 F 4.44        ... ... --- --- --- --- a-- --- --- --- --- --- ... --- --- -c- --- --- --- ---
                                                              N                                   A                 
  X92237   IGHV4-34*05 F 4-44.3      ... ... --- --- --- --- a-- --- --- --- --- --- ... --- --- -c- --- --- --- ---
                                                                                                                    
  X92256   IGHV4-34*06 F VH4-MC5a    ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  X92258   IGHV4-34*07 F VH4-MC5c    ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  M95113   IGHV4-34*08 F H3          ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  Z14241   IGHV4-34*09 F 4.36        ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --t --- --- --- ---
                                                                                                  I       M         
  Z14242   IGHV4-34*10 F 4.37        ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- a-- --- --g --- ---
                                                              N                                   A                 
  X05716   IGHV4-34*11 F V58         ... ... --g --- --- --- a-- --- --c --- --- --- ... --- --- -c- --- --- --- ---
                                                                                                                    
  X56591   IGHV4-34*12 F TouVH4.21   ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                    
  Z75356   IGHV4-34*13 F VH4-GL4     ... ... --- --- --- --- --- --- --c --- --- --- ... --- --- --- --- --- --- ---


                                                                                                                     
                                     
                                      81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                      D   T   S   K   N   Q   F   S   L   K   L   S   S   V   T   A   A   D   T   A 
  AB019439 IGHV4-34*01 F             gac acg tcc aag aac cag ttc tcc ctg aag ctg agc tct gtg acc gcc gcg gac acg gct
                                                                                                                    
  X92278   IGHV4-34*01 F VH5         --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  L10090   IGHV4-34*01 F 4d76        --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  Z12363   IGHV4-34*01 F DP-63       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X56364   IGHV4-34*01 F VH4.21      --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  Z75354   IGHV4-34*01 F VH4-GL20    --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  M99684   IGHV4-34*02 F V4-34       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92255   IGHV4-34*03 F VH4-MC5     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --c
                                                                                                                    
  X92257   IGHV4-34*03 F VH4-MC5b    --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --c
                                                                                                                    
  X92236   IGHV4-34*04 F 4.44        --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  X92237   IGHV4-34*05 F 4-44.3      --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                  G                                 
  X92256   IGHV4-34*06 F VH4-MC5a    --- --- --- --- --- --- --- --- --- --- --- g-- --- --- --- --- --- --- --- --c
                                                                                                                    
  X92258   IGHV4-34*07 F VH4-MC5c    --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --c
                                                                                                                    
  M95113   IGHV4-34*08 F H3          --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  Z14241   IGHV4-34*09 F 4.36        --- --- --t --- --- --- --- --- --- --- --- --- --- --- --t --- --- --- --- --c
                                                                  Y                                                 
  Z14242   IGHV4-34*10 F 4.37        --- --- --- --- --- --- --- -a- --- --- --- --- --- --- --- --- --- --- --- --c
                                                                          N                                         
  X05716   IGHV4-34*11 F V58         --- --- --- --- --- --- --- --- --- --c --- --- --- --- --- --- --- --- --- --c
                                                                                                                    
  X56591   IGHV4-34*12 F TouVH4.21   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                    
  Z75356   IGHV4-34*13 F VH4-GL4     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                     _CDR3-IMGT__
                                     
                                     101 102 103 104 105 106 
                                      V   Y   Y   C   A   R  
  AB019439 IGHV4-34*01 F             gtg tat tac tgt gcg aga gg
                                                             
  X92278   IGHV4-34*01 F VH5         --- --- --- --- --- --- --
                                                             
  L10090   IGHV4-34*01 F 4d76        --- --- --- --- --- --- --
                                                             
  Z12363   IGHV4-34*01 F DP-63       --- --- --- --- --- --- 
                                                             
  X56364   IGHV4-34*01 F VH4.21      --- --- --- --- --- --- 
                                                             
  Z75354   IGHV4-34*01 F VH4-GL20    --- --- --- - 
                                                             
  M99684   IGHV4-34*02 F V4-34       --- --- --- --- --- --- --
                                                 
  X92255   IGHV4-34*03 F VH4-MC5     --- --- --- --
                                                 
  X92257   IGHV4-34*03 F VH4-MC5b    --- --- --- --
                                                             
  X92236   IGHV4-34*04 F 4.44        --- --- --- --- --- --- --
                                                             
  X92237   IGHV4-34*05 F 4-44.3      --- --- --- --- --- --- --
                                                 
  X92256   IGHV4-34*06 F VH4-MC5a    --- --- --- --
                                                 
  X92258   IGHV4-34*07 F VH4-MC5c    --- --- --- --
                                                         
  M95113   IGHV4-34*08 F H3          --- --- --- --- --- 
                                                             
  Z14241   IGHV4-34*09 F 4.36        --- --- --- --- --- --- -a
                                                             
  Z14242   IGHV4-34*10 F 4.37        --- --- --- --- --- --- ta
                                              C              
  X05716   IGHV4-34*11 F V58         --- --- -g- --- --- --- -a
                                                             
  X56591   IGHV4-34*12 F TouVH4.21   --- --- --- --- --- --- 
                                                             
  Z75356   IGHV4-34*13 F VH4-GL4     --- --- --- --- --- --- --

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
07/08/1997
Last updated:
27/05/2016
Authors:
Joumana Jabado-Michaloud, Dominique Scaviner and Nathalie Pallarès