Alignment of alleles: Atlantic salmon (Salmo salar) IGHV2S2

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Germline genomic sequences are needed to confirm if the nucleotide substitutions result from somatic mutations or correspond to allelic polymorphisms.

                                  1   2   3   4   5   6  6A  6B   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                 G   Q   S   L   E   V   I   P   S   S   P       V   Q   K   K   P   G   E   T   L   S
  AF273401,IGHV2S2*01           GGT CAG AGT CTG GAG GTC ATT CCC TCC AGT CCA ... GTC CAG AAA AAG CCT GGA GAA ACT CTC AGT

  AF269073,IGHV2S2*02           --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---

                                                        ___________________CDR1-IMGT____________________
                                 21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                 L   S   C   K   I   S   G   Y   T   V   T   S   H   H                   T   H
  AF273401,IGHV2S2*01           CTG TCC TGT AAG ATA TCT GGA TAT ACC GTT ACC AGC CAC CAC ... ... ... ... ACA CAC

  AF269073,IGHV2S2*02           --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---

                                                                                            _______________CDR2-
                                 41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                 W   I   R   Q   P   A   G   K   S   L   E   W   M   G   F   S   G   L   G   L
  AF273401,IGHV2S2*01           TGG ATA CGA CAG CCA GCA GGA AAA TCC CTG GAG TGG ATG GGT TTT TCT GGA TTA GGC CTA

  AF269073,IGHV2S2*02           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                IMGT________________
                                 61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                 G                   Y   H   A   K   K   F   E       G   R   M   E   T   T   K
  AF273401,IGHV2S2*01           GGT ... ... ... ... TAC CAT GCT AAA AAG TTT GAA ... GGA CGT ATG GAA ACC ACT AAA

  AF269073,IGHV2S2*02           --- ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---


                                 81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                 D   T   R   N   S   M   L   T   L   M   L   S   G   V   R   A   E   D   S   A
  AF273401,IGHV2S2*01           GAT ACT AGA AAC AGC ATG TTG ACT TTG ATG CTG TCT GGT GTG AGA GCA GAG GAC TCT GCT
                                                                                             V  
  AF269073,IGHV2S2*02           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -T- --- --- --- ---

                                                CDR3-IMGT
                                101 102 103 104 105 106 
                                 V   Y   Y   C   A   R
  AF273401,IGHV2S2*01           GTG TAT TAC TGT GCA AGA     #c

  AF269073,IGHV2S2*02           --- --- --- --- --- ---     #c


#c: rearranged cDNA


Created: 11/12/2001
Author: Nathalie Bosc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

CNRS Université de Montpellier European Commission
IMGT® Founder and Executive Director Emeritus:
Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
IMGT® Director:
Sofia Kossida Sofia.Kossida@igh.cnrs.fr
Bioinformatics manager:
Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr
Computer manager:
Patrice Duroux Patrice.Duroux@igh.cnrs.fr
Webmaster:
Amélie Houles

Citing IMGT | Warranty disclaimer and copyright notice | Privacy policy and advertisement policy

© Copyright 1995-2018 IMGT®, the international ImMunoGeneTics information system®