Alignment of alleles: Atlantic salmon (Salmo salar) IGHV7S1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Germline genomic sequences are needed to confirm if the nucleotide substitutions result from somatic mutations or correspond to allelic polymorphisms.

                                  1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                 G   L   E   F   T   Q   P   S   S       L   D   V   K   P   G   E   S   L   S
  AF273433,IGHV7S1*01           GGA CTT GAG TTC ACC CAA CCA AGC TCA ... TTG GAT GTA AAG CCT GGA GAG TCT TTG AGC

                                                        ___________________CDR1-IMGT____________________
                                 21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                 I   T   C   K   V   S   G   Y   S   L   T   D   S   T   N   L   H   G   I   G
  AF273433,IGHV7S1*01           ATC ACC TGT AAA GTC TCT GGT TAT TCT CTG ACT GAT AGC ACC AAC CTC CAT GGA ATA GGC

                                                                                            _______________CDR2-
                                 41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                 W   I   R   H   P   T   G   K   A   L   E   W   I   W   T   I   Y   Y   D   G
  AF273433,IGHV7S1*01           TGG ATC CGA CAT CCT ACA GGA AAA GCA CTT GAA TGG ATT TGG ACC ATC TAT TAT GAT GGA

                                IMGT________________
                                 61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                 S   S               N   S   Q   S   S   L   K       D   R   F   S   F   T   R
  AF273433,IGHV7S1*01           AGC TCA ... ... ... AAC TCT CAA AGT TCC CTA AAA ... GAC AGG TTC AGT TTC ACA AGA


                                 81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                 D   T   S   S   N   T   V   F   L   K   G   Q   S   L   Q   T   E   D   T   A
  AF273433,IGHV7S1*01           GAC ACT TCC AGC AAC ACA GTG TTT TTA AAA GGA CAG AGT CTG CAG ACT GAA GAC ACA GCT

                                                CDR3-IMGT
                                101 102 103 104 105 106
                                 V   Y   Y   C   A   R
  AF273433,IGHV7S1*01           GTG TAT TAC TGT GCT CGG    #c



#c: rearranged cDNA


Created: 11/12/2001
Author: Nathalie Bosc

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For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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