Table of alleles: Human IGHV

Print of this table: Pallarès, N. et al., Exp. Clin. Immunogenet., 16, 36-60 (1999). PMID:10087405
UPDATE: Human IGHV (10/2002)

Since October 2012, new IGHV alleles are not reported in this table. For the polymorphism description, you can refer to the following Alignments of alleles.

The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.

Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).

Because of STOP-CODON (in frame) at position 39, but the gene has been found rearranged. For that reason the IGHV4-55 gene has been added to IMGT/V-QUEST (May 2005).

IGHV subgroupIGHV
gene name
FctIGHV
allele name
Accession numberconfirmed by genetics and/or dataDescription of mutations
1IGHV1-2FIGHV1-2*01X07448+c44  ,P15  |c163  ,R55  |a223  ,R75  |g233  ,t234  ,S78  |t299  ,V100  |
FIGHV1-2*02X62106+           |c163>t,R55>W|            |g233>t,t234>g,S78>M|t299>c,V100>A|
FIGHV1-2*03X92208 c44>t,P15>L|c163>t,R55>W|            |g233>t,t234>g,S78>M|t299>c,V100>A|
FIGHV1-2*04Z12310            |c163>t,R55>W|a223>t,R75>W|g233>t,t234>g,S78>M|t299>c,V100>A|
FIGHV1-2*05HM855674+                                     |g233>t,t234>g,S78>M|
IGHV1-3FIGHV1-3*01X62109+c6  |t12  |t167  ,I56  |a208  ,K70  |a291  |c296  ,T99  |
FIGHV1-3*02X62107 c6>t|t12>g|t167>g,I56>S|a208>g,K70>E|a291>g|c296>t,T99>M|
IGHV1-8FIGHV1-8*01M99637+ 
FIGHV1-8*02HM855457        t108>c|                                
IGHV1-18FIGHV1-18*01M99641+g282  |
FIGHV1-18*02X60503 g282>a|
FIGHV1-18*03HM855463                                             c296>t,T99>M|
IGHV1-24FIGHV1-24*01M99642+ 
IGHV1-45FIGHV1-45*01X92209 g139  ,G47  |t237  |
FIGHV1-45*02AB019438             |t237>c|
FIGHV1-45*03Z17391 g139>a,G47>R|t237>c|
IGHV1-46FIGHV1-46*01X92343+c92  ,T31  |g315  |
FIGHV1-46*02J00240 c92>a,T31>N|
FIGHV1-46*03L06612            |g315>t|
IGHV1-58FIGHV1-58*01M29809+g115  ,V39  |
FIGHV1-58*02AB019438 g115>a,V39>M|
IGHV1-69FIGHV1-69*01L22582 +g6  |g18  |g54  |g100  ,A34  |g163  ,G55  |t178  ,F60  |c185  ,T62  |g238  ,A80  |g244  ,E82  |g291  ,E97  |
FIGHV1-69*02Z27506+g6>c|g18>a|     |g100>a,A34>T|g163>a,G55>R|t178>c,F60>L|c185>t,T62>I|            |g244>a,E82>K|
FIGHV1-69*03X92340                                                                                               |g291>t,E97>D|
FIGHV1-69*04M83132
+
g6>c|                        |g163>a,G55>R|t178>c,F60>L|c185>t,T62>I|            |g244>a,E82>K|
FIGHV1-69*05X67905 g6>c|                                                               |g238>a,A80>T|
FIGHV1-69*06L22583+                                                                                 |g244>a,E82>K|
FIGHV1-69*07Z29978                              |g163>a,G55>R|
FIGHV1-69*08Z14309 g6>c|g18>a|     |g100>a,A34>T|g163>a,G55>R|t178>C,F60>L|                         |g244>a,E82>K|                  
FIGHV1-69*09Z14307                              |g163>a,G55>R|t178>c,F60>L|c185>t,T62>I|            |g244>a,E82>K|
FIGHV1-69*10Z14300 g6>c|     |g54>a|                         |t178>c,F60>L|c185>t,T62>I|            |g244>a,E82>K|
FIGHV1-69*11Z14296
+
g6>c|                        |g163>a,G55>R|t178>c,F60>L|
FIGHV1-69*12Z14301
+
g6>c
(F)IGHV1-69*13Z14214(st)
+
g6>c|     |g54>a|
IGHV1-cORFIGHV1-c*01HM855760  
IGHV1-fFIGHV1-f*01Z12305 c201  |
FIGHV1-f*02Z29977 c201>t|
2IGHV2-5FIGHV2-5*01X62111 a4  ,I2  |a31  ,T11  |g39  |g60  |g103  ,V35  |g106  ,G36  |g118  ,G40  |a175  ,N59  |a202  ,S68  |c234  |c299  ,A100  |c314  ,A105  |a317  ,c318  ,H106  |
FIGHV2-5*02Z14072+                                                                        |a175>g,N59>D|
FIGHV2-5*03X93619                                                                         |a175>g,N59>D|            |c234>t|
FIGHV2-5*04L21963                                                                                                          |c299>g,A100>G|c314>t,A105>V|a317>g,c318>g,H106>R|
FIGHV2-5*05L21964                                                                         |a175>g,N59>D|a202>g,S68>G|
FIGHV2-5*06L21966                      |g39>a|                                            |a175>g,N59>D|a202>g,S68>G|
FIGHV2-5*07L21968                                                                                                          |c299>g,A100>G|c314>t,A105>V|
FIGHV2-5*08L21971 a4>g,I2>V|a31>g,T11>A|     |g60>a|g103>a,V35>M|g106>c,G36>R|g118>a,G40>S|a175>g,N59>D|
FIGHV2-5*09L21972 a4>g,I2>V|                                                              |a175>g,N59>D|a202>g,S68>G|
FIGHV2-5*10X69690                                                                         |a175>g,N59>D|                                               |a317>g,c318>g,H106>R|                                       
IGHV2-26FIGHV2-26*01M99648+ 
IGHV2-70FIGHV2-70*01L21969+a2  ,Q1  |g4  ,V2  |g14  ,R5  |g31  ,A11  |a60  |t67  ,C23  |a70  ,T24  |t106  ,C36  |t116  ,V39  |a138  |c157  ,L53  |t164  ,L55  |a197  ,Y66  |t210  |g216  ,K72  |a297  |c299  ,A100  |a301  ,c302  ,T101  |g303  |c309  |c314  ,A105  |g317  ,g318  ,R106  |t320  ,I107  |
FIGHV2-70*02X92241+                                                                                                                                                                    |a297>g|             |a301>g,c302>t,T101>V|
FIGHV2-70*03X92238+                   |g14>a,R5>K|                                         |t106>c,C36>R|                                |t164>g,L55>R|a197>t,Y66>F|                   |a297>g|             |a301>g,c302>t,T101>V|
FIGHV2-70*04Z12330                    |g14>a,R5>K|                                         |t106>c,C36>R|                                |t164>g,L55>R|a197>t,Y66>F|
FIGHV2-70*05Z27502                                                                         |t106>c,C36>R|t116>c,V39>A|                   |t164>g,L55>R|a197>t,Y66>F|
FIGHV2-70*06X92239                    |g14>a,R5>K|                                         |t106>c,C36>R|                                |t164>g,L55>R|a197>t,Y66>F|t210>c|            |a297>g|             |a301>g,c302>t,T101>V|
FIGHV2-70*07X92243                                                                                                   |a138>g|                                                          |a297>g|             |a301>g,c302>t,T101>V|
FIGHV2-70*08X92245                                                             |a70>g,T24>A|                                             |t164>g,L55>R|                                |a297>g|             |a301>g,c302>t,T101>V|
FIGHV2-70*09L21962          |g4>a,V2>I|g14>a,R5>K|g31>a,A11>T|a60>g|t67>c,C23>R|                                                                                          |g216>c,K72>N|      |c299>g,A100>G|                    |g303>a|      |c314>t,A105>V|
FIGHV2-70*10L21965                    |g14>a,R5>K|                                         |t106>c,C36>R|                   |c157>a,L53>I|t164>g,L55>R|
FIGHV2-70*11L21967 a2>g,Q1>R|                                                                                                            |t164>g,L55>R|
FIGHV2-70*12L21970          |g4>a,V2>I|g14>a,R5>K|g31>a,A11>T|a60>g|                                                                                                                                                             |g303>a|                     |g317a,g318>c,R106>H|t320>g,I107>R|
FIGHV2-70*13AB019437                                                                                                                                                                                                                      |c309>t|
3IGHV3-7FIGHV3-7*01M99649+g144  |
FIGHV3-7*02X92288 g144>a|
FIGHV3-7*03HM855666                                             t300>c|
IGHV3-9FIGHV3-9*01M99651+ 
FIGHV3-9*02HM855577                                 t88>c, F30>S|
IGH3-11FIGHV3-11*01M99652+          |g13  ,V5  |g32     ,G11     |g47     ,G16     |g178  ,G60  |a184  ,c185  ,T62  |t188  ,I63  |t196  ,Y66  |a206     ,D69     |g240  |c243  ,D81  |c296     ,g297     ,T99     |g301  ,g303  ,V101  |t304  ,a305  ,Y102  |t307  ,a308  ,c309  ,Y103  |t312  |c314  ,A105  |
PIGHV3-11*02M15496 9^10>ins^t|          |g32>del#,G11>del#|g47>del#,G16>del#|                                                          |a206>del#,D69>del#|      |c243>g,D81>E|c296>del#,g297>del#,T99>del#|g301>t,g303>a,V101>L|t304>c,a305>t,Y102>L|t307>a,a308>c,c309>t,Y103>T|t312>c|c314>a,A105>E|
FIGHV3-11*03X92287           |g13>t,V5>L|                                   |g178>a,G60>S|a184>t,c185>a,T62>Y|t188>c,I63>T|t196>a,Y66>N|                  |g240>a|
FIGHV3-11*04HM855329+                                                                                                             c300>t|          
FIGHV3-11*05HM855583+                                                          g178>a, G60>S|          
IGHV3-13FIGHV3-13*01X92217+g9  ,Q3  |t52  ,S18  |g77  ,S26  |g95  ,S32  |t165  |t167  ,I56  |c222  |g224  ,R75  |
FIGHV3-13*02M99653 g9>t,Q3>H|t52>g,S18>A|           |g95>a,S32>N|t165>c|t167>a,I56>N|c222>g|
FIGHV3-13*03U29582                      |c77>g,S26>C|                                      |g224>a,R75>Q|
FIGHV3-13*04HM855616                                                            |g153>a|
IGHV3-15FIGHV3-15*01X92216+g23  ,g24  ,G8  |g32  ,G11  |a40  ,K14  |a81  |t89  ,F30  |g119  ,S40  |t159  |c163  ,R55  |a169  ,K57  |a178  ,T60  |g181  ,D61  |g196  ,D66  |c210  |a242  ,D81  |a275  ,N92  |c279  |a297  |a320  |
FIGHV3-15*02M99654                 |g32>c,G11>A|
FIGHV3-15*03M99408+g23>c,g24>c,G8>A|g32>c,G11>A|a40>c,K14>Q|     |t89>g,F30>C|                                             |a178>g,T60>A|g181>a,D61>N|            |c210>t|a242>t,D81>V|
FIGHV3-15*04M99402                                                                                            |a169>g,K57>E|
FIGHV3-15*05M99403                                                                                                                                                                                 |c279>t|
FIGHV3-15*06M99404                                                                        |t159>c|                                                   |g196>a,D66>N|
FIGHV3-15*07M99406                                         |a81>t|           |g119>a,S40>N|t159>c|
FIGHV3-15*08M99400 g23>c      ,G8>A|           |a40>c,K14>Q|     |t89>g,F30>C|                   |c163>t,R55>C|            |a178>g,T60>A|g181>a,D61>N|            |c210>t|            |a275>t,N92>I|      |a297>g|a320>g|
IGHV3-16ORFIGHV3-16*01M99655 a6  |a9  |
ORFIGHV3-16*02AB019440 a6>g|a9>g|
IGHV3-19PIGHV3-19*01M99656+ 
IGHV3-20FIGHV3-20*01M99657+t68  ,C23  |
IGHV3-21FIGHV3-21*01AB019439+g9  |
FIGHV3-21*02M99658 g9>a|
FIGHV3-21*03HM855323                                                                 g297>a|
FIGHV3-21*04HM855688                                                                                t300>c|
IGHV3-23FIGHV3-23*01M99660+c164  ,A55  |a169  ,g170  ,S57  |g172  ,t174  ,G58  |a175  ,S59  |g181  ,G61  |c201  |c203  ,A68  |c237  |c243  |
FIGHV3-23*02M35415
+
                                                                                     |c203>g,A68>G|c237>a|
FIGHV3-23*03AM940223 c164>t,A55>V|a169>t,g170>a,S57>Y|g172>a,t174>c,G58>S|a175>g,S59>G|g181>a,G61>S|c201>t|                   |c243>t|
FIGHV3-23*04AJ879486
+
t13>g|
FIGHV3-23*05AY757302
+
a154>t, g155>a, S>Y|g157>a, t159>a, G>S|g166>a, G>S|
IGHV3-30FIGHV3-30*01M83134+g18  ,E6  |a27  |a49  ,R17  |c75  |g80  ,G27  |c101  ,t102  ,A34  |t135  |a138  |a150  |g163  ,V55  |t169  ,c170  ,a171  ,S57  |c201  |g202  ,A68  |a229  ,T77  |c257  ,T86  |g267  |a275  ,N92  |t288  |a293  ,D98  |g317  ,R106  |
FIGHV3-30*02L26401+                |a49>g,R17>G|c75>g|           |c101>g,t102>c,A34>G|             |a150>g|g163>t,V55>F|t169>c,c170>g,a171>g,S57>R|c201>t|                                                                              |g317>a,R106>K|
FIGHV3-30*03M99663                                               |c101>g,t102>c,A34>G|             |a150>g|                                       |c201>t|
FIGHV3-30*04L06615+                                                                                |a150>g|
FIGHV3-30*05M77323                                               |c101>g,t102>c,A34>G|                                                                                                                                     |a293>g,D98>G|
FIGHV3-30*06L06617+                            |c75>g|           |c101>c,t102>c,A34>G|
FIGHV3-30*07L06614+                                                                                                                                                                                                 |t288>c|
FIGHV3-30*08M62737 g18>c,E6>D|                       |g80>c,G27>A|
FIGHV3-30*09M77300                                                                                 |a150>g|                                                           |a229>g,T77>A|
FIGHV3-30*10M77326                                                                                                                                       |g202>a,A68>T|
FIGHV3-30*11M77331                             |c75>g|
FIGHV3-30*12M77338           |a27>g|           |c75>g|           |c101>g,t102>c,A34>G|                                                                                                                              |t288>c|
FIGHV3-30*13M77339                                               |c101>g,t102>c,A34>G|                                                                                             |c257>g,T86>R|
FIGHV3-30*14M77324                                                                                 |a150>g|                                                                                     |g267>t|
FIGHV3-30*15M77327                                                                                                                                                                                     |a275>g,N92>S|
FIGHV3-30*16M77328                                                                   |t135>c|
FIGHV3-30*17M77329                                                                          |a138>g|
FIGHV3-30*18X92214+                                              |c101>g,t102>g,A34>G|             |a150>g|                                       |c201>t|                                                                              |g317>a,R106>K|
FIGHV3-30*19L06616+                            |c75>g|           |c101>g,t102>g,A34>G|             |a150>g|
IGHV3-30-3FIGHV3-30-3*01X92283+c75  |g317  ,R106  |
FIGHV3-30-3*02M77302 c75>g|g317>a,R106>K|
IGHV3-33FIGHV3-33*01AB019439+g6  |g150  |g170  ,g171  ,W57  |t177  |t212  ,V71  |t246  |a251  ,K84  |a263  ,Y88  |g317  ,R106  |
FIGHV3-33*02M99665 g6>a|                                 |t212>c,V71>A|      |a251>c,K84>T|a263>t,Y88>F|
FIGHV3-33*03M77305                                                    |t246>c|                         |g317>a,R106>K|
FIGHV3-33*04M77335     |g150>a|                   |t177>c|
FIGHV3-33*05M77334            |g170>c,g171>a,W57>S|
FIGHV3-33*06HM855436                                                                                            |g317>a, R106>K|
IGHV3-35ORFIGHV3-35*01M99666+ 
IGHV3-38ORFIGHV3-38*01M99669 c302  ,A101  |
ORFIGHV3-38*02AB019439 c302>t,A101>V|
IGHV3-43FIGHV3-43*01M99672+t32  ,V11  |a100  ,T34  |g138  |t172  ,W58  |
FIGHV3-43*02HM855392 t32>g,V11>G|a100>g,T34>A|g138>a|t172>g,W58>G|
IGHV3-47PIGHV3-47*01Z18900 c58  |c101  ,A34  |t149  ,L50  |t267     ,L89     |t270  ,H90  |t310  |
PIGHV3-47*02AB019438 c58>a|c101>t,A34>V|t149>c,L50>P|                  |t270>a,H90>Q|
PIGHV3-47*03M99674 c58>a|c101>t,A34>V|t149>c,L50>P|t267>del#,L89>del#|t270>a,H90>Q|t310>g|
IGHV3-48FIGHV3-48*01M99675+g48  |c96  |a100  ,g101  ,c102  ,S34  |a178  ,S60  |t246  |c287  ,A96  |g303  |
FIGHV3-48*02AB019438                                                           |c287>a,A96>D|
FIGHV3-48*03U03893+g48>a|c96>t|a100>g,g101>a,c102>a,S34>E|a178>g,S60>G|t246>c|            |g303>t|
FIGHV3-48*04HM855336                                                           |t246>c|
IGHV3-49FIGHV3-49*01M99676 g50  ,R17  |t93  |g94  ,D32  |g100  ,A34  |t124  ,F42  |a202  ,T68  |g245  ,G82  |
FIGHV3-49*02M99401 g50>c,R17>P|t93>g|g94>t,D32>Y|g100>c,A34>P|t124>g,F42>V|a202>g,T68>A|g245>a,G82>D|
FIGHV3-49*03AB019438                                                        |a202>g,T68>A|g245>a,G82>D|
FIGHV3-49*04AM940220                                           |t124>g ,F42>V|a202>g,T68>A|g245>a,G82>D|
FIGHV3-49*05AM940221                                                        |a202>g,T68>A|g245>a,G82>D|
IGHV3-53FIGHV3-53*01M99679 t19  ,S7  |g133  ,A45  |c210  |g315  |a318  |
FIGHV3-53*02Z12342 t19>a,S7>T|
FIGHV3-53*03J03617           |g133>c,A45>P|c210>t|g315>t|a318>g|
FIGHV3-53*04HM855453         |a37>,I13>V|       |g241>c, D81>H|
IGHV3-64FIGHV3-64*01M99682+g1  ,E1  |g26  ,G9  |g70  ,A24  |t198  |t201  |a205  ,N69  |t210  |c265  ,t267  ,L89  |g274  ,g275  ,G92  |c279  |t296  ,M99  |c314  ,A105  |g317  ,R106  |
FIGHV3-64*02AB019437          |g26>a,G9>E|                         |a205>g,N69>D|
FIGHV3-64*03M77298                     |g70>t,A24>S|t198>c|t201>c|a205>g,N69>D|t210>a|c265>g,t267>c,L89>V|g274>a       ,G92>S|c279>t|t296>c,M99>T|c314>t,A105>V|g317>a,R106>K|
FIGHV3-64*04M77299 g1>c,E1>Q|          |g70>t,A24>S|t198>c|t201>c|a205>g,N69>D|t210>a|      ,t267>g,     |g274>a,g275>a,G92>N|      |t296>c,M99>T|                           
FIGHV3-64*05M77301                     |g70>t,A24>S|t198>c|t201>c|a205>g,N69>D|t210>a|c265>g,      ,L89>V|g274>a       ,G92>S|c279>t|t296>c,M99>T|c314>t,A105>V|g317>a,R106>K|
IGHV3-66FIGHV3-66*01X92218 g24  |g37  ,V13  |a81  |g175  ,G59  |a223  |c288  |g319  |
FIGHV3-66*02Z27504                                     |a223>c|c288>t|
FIGHV3-66*03AB019437+g24>a|g37>a,V13>I|a81>g|g175>t,G59>C|a223>c|c288>t|                          
FIGHV3-66*04X70208+                                                  |g319>c|
IGHV3-72FIGHV3-72*01X92206+t186  |
FIGHV3-72*02Z29979 t186>c|
IGHV3-73FIGHV3-73*01X70197+t21  |
FIGHV3-73*02AB019437 t21>c|
IGHV3-74FIGHV3-74*01L33851+c21  |g197  ,c198  ,S66  |
FIGHV3-74*02Z17392 c21>t|
FIGHV3-74*03J00239      |g197>c,c198>g,S66>T|
IGHV3-dFIGHV3-d*01Z18898  
IGHV3-hP(1)IGHV3-h*01AJ879484+ 
P(1)IGHV3-h*02AJ879485+                                               |g303>t|
IGHV3-NL1FIGHV3-NL1*01HM855939  
4IGHV4-4FIGHV4-4*01X05713+c20  ,S7  |c46  ,P16  |g50  ,G17  |g70  ,A24  |g73  ,V25  |c93  |a97  ,g98  ,t99  ,S33  |a100  ,N34  |t120  |g124  ,V42  |c129  |c136  ,a138  ,P46  |g147  |g163  ,a164  ,a165  ,E55  |c172  ,a173  ,t174  ,H58  |g207  |a234  ,I78  |a245  ,K82  |g308  ,C103  |
FIGHV4-4*02X92232+          |c46>t,P16>S|                                                                                                                                                                                                                           |g308>a,C103>Y|
FIGHV4-4*03X92252+                                                                                                                                                                                                                                                  |g308>a,C103>Y|
FIGHV4-4*04X92253+                                               |g73>a,V25>I|                                                                                                                                                                                       |g308>a,C103>Y|
FIGHV4-4*05X92254 c20>t,S7>L|                                                                                                                                                                                                                                       |g308>a,C103>Y|
FIGHV4-4*06Z75355                                                                                                                                                                                                                         |a234>g,I78>M|a245>c,K82>T|g308>a,C103>Y|
FIGHV4-4*07X62112           |c46>t,P16>S|g50>a,G17>E|g70>a,A24>T|           |c93>t|a97>t,g98>a,t99>c,S33>Y|a100>t,N34>Y|t120>c|g124>a,V42>I|c129>g|c136>g,a138>c,P46>A|g147>a|g163>c,a164>g,a165>t,E55>R|c172>a,a173>c,t174>c,H58>T|g207>c|a234>g,I78>M|a245>c,K82>T|g308>a,C103>Y|                                               |a234>g,I78>M|a245>c,K82>T|g308>a,C103>Y|
IGHV4-28FIGHV4-28*01X05714+g6  |g48  |g49  ,c51  ,D17  |c185  ,T62  |g297  |c299  ,A100  |a319  |
FIGHV4-28*02M83133+     g48>a|g49>c,c51>g,D17>Q|c185>t,T62>I|                    
FIGHV4-28*03X92233                                                               |a319>g|
FIGHV4-28*04X56358                                          |g297>c|c299>g,A100>G|
FIGHV4-28*05HM855339                             |c194>t, T65>I|
FIGHV4-28*06HM855782                                |t196>a, Y66>N|
IGHV4-30-2FIGHV4-30-2*01L10089+t163  ,a164  ,c165  ,Y55  |c172  ,H58  |a237  |g245  ,R82  |c288  |g291  |c300  |c315  |g319  |
FIGHV4-30-2*02M95122                                                            |c288>t|             |c315>g|
FIGHV4-30-2*03X92229 t163>a,a164>g,c165>t,Y55>S|c172>t,H58>Y|a237>c|g245>c,R82>T|c288>t|g291>a|c300>t|c315>g|g319>c|
FIGHV4-30-2*04Z75351                                               |g245>c,R82>T|      |g291>a|         |c315>g|
FIGHV4-30-2*05HM855593          |c228>t|                                   |g245>c,R82>T|   |c285>t|      |g291>a|
IGHV4-30-4FIGHV4-30-4*01Z14238+g18  ,E6  |a48  |c49  ,g51  ,Q17  |c134  ,P45  |a166  ,I56  |t228  |c288  |a291  |
FIGHV4-30-4*02Z14239           |a48>g|c49>g,g51>c,Q17>D|                                |c288>a|
FIGHV4-30-4*03X92274                                                                           |a291>g|
FIGHV4-30-4*04X92275 g18>c,E6>D|                                    |a166>t,I56>F|
FIGHV4-30-4*05Z75353                                                             |t228>c|
FIGHV4-30-4*06Z75360                                   |c134>a,P45>H|
IGHV4-31FIGHV4-31*01L10098 a8  ,Q3  |g37  ,V13  |c69  |c84  |g100  ,G34  |a164  ,Y55  |t224  ,L75  |a237  |a244  ,c245  ,T82  |t249  |t285  |t285-c287          |a295  ,T99  |t304  ,Y102  |
FIGHV4-31*02M99683+                     |c69>t|                               |t224>g,L75>R|
FIGHV4-31*03Z14237+                                                           |t224>g,L75>R|
FIGHV4-31*04M95120 a8>g,Q3>R|                                                 |t224>g,L75>R|
FIGHV4-31*05M95121                                                            |t224>g,L75>R|                                        |t285-c287>del(3nt)#|a295>g,T99>A|
FIGHV4-31*06X92270                                  |g100>a,G34>S|            |t224>g,L75>R|
FIGHV4-31*07X92271                            |c84>a|                         |t224>g,L75>R|
FIGHV4-31*08X92272                                                            |t224>g,L75>R|a237>c|                   |t249>c|
FIGHV4-31*09X92273                                                            |t224>g,L75>R|      |      ,c245>a,T82>K|t249>c|t285>c|
FIGHV4-31*10Z14235          |g37>t,V13>L|                        |a164>g,Y55>C|t224>g,L75>R|      |a244>c,      ,T82>P|t249>c|                                       |t304>g,Y102>D|
IGHV4-34FIGHV4-34*01AB019439+a12  |g15  |c16  ,Q6  |g20  ,W7  |g25  ,A9  |t37  ,L13  |g48  |g49  ,E17  |t85  ,S29  |t88  ,F30  |a118  ,S40  |c129  |c137  ,P46  |g147  |g163  ,a165  ,E55  |a169  ,a170  ,t171  ,N57  |c172  ,H58  |a180  |t199  ,Y67  |g207  |g226  ,t227  ,c228  ,V76  |a234  ,I78  |c249  |c263  ,S88  |g270  ,K90  |a274  ,S92  |c285  |t300  |a308  ,Y103  |
FIGHV4-34*02M99684      |g15>a|
FIGHV4-34*03X92255+                                                                                                                                                                                                                                                                                                                              |t300>c|
FIGHV4-34*04X92236                                                                                                                                                                                                              |t199>a,Y67>N|      |      ,t227>c       ,V76>A|
FIGHV4-34*05X92237                                                                                                   |a118>t,S40>C|      |c137>t,P46>L|                                                                         |t199>a,Y67>N|      |      ,t227>c       ,V76>A|
FIGHV4-34*06X92256                                                                                                                                                                                                                                                                                                           |a274>g,S92>G|      |t300>c|
FIGHV4-34*07X92258                                                                                                                                                               |             ,t171>c      |                                                                                                                                    |t300>c|
FIGHV4-34*08M95113                                                                           |t85>a,S29>T|
FIGHV4-34*09Z14241 a12>g|     |c16>g,Q6>E|g20>c,W7>S|g25>c,A9>P|t37>g,L13>V|g48>a|g49>c,E17>Q|                                                        |g147>a|                                                                                      |              c228>t      |            |c249>t|                                      |c285>t|t300>c|
FIGHV4-34*10Z14242 a12>g|     |c16>g,Q6>E|g20>c,W7>S|g25>c,A9>P|t37>g,L13>V|                                                                          |g147>a|                                                                                      |g226>a,             ,V76>I|a234>g,I78>M|      |c263>a,S88>Y|                                |t300>c|
FIGHV4-34*11X05716                                                                                       |t88>g,F30>V|            |c129>g|                   |g163>t,a165>t,E55>Y|a169>t              ,N57>Y|c172>t,H58>Y|a180>g|t199>a,Y67>N|g207>c|       t227>c       ,V76>A|                                |g270>c,K90>N|                   |t300>c|a308>g,Y103>C|
FIGHV4-34*12X56591                                                                                                                                                               |      a170>t        ,N57>I|
FIGHV4-34*13Z75356                                                                                                                                                                                                                           |g207>c|                                                                   
IGHV4-39FIGHV4-39*01AB019439+a2  ,Q1  |t56  ,L19  |c237  |g258  ,Q86  |t262  ,S88  |a291  |t300  |c319  |
FIGHV4-39*02X05715                             |g258>c,Q86>H|                          |c319>g|
FIGHV4-39*03X92259                                                              |t300>c|
FIGHV4-39*04X92297                                                       |a291>g|
FIGHV4-39*05M95116          |t56>c,L19>P|
FIGHV4-39*06Z14236 a2>g,Q1>R|           |c237>a|            |t262>c,S88>P|a291>g|t300>c|
FIGHV4-39*07AM940222                      |c237>a|                         |a291>g|t300>c|   c319>g
IGHV4-55PIGHV4-55*01M99685+c44  ,P15  |c237  |a251  ,K84  |c255  ,N85  |a263  ,Y88  |c288  |c290  ,A97  |g291  |t319  |
PIGHV4-55*02X92223            |c237>a|
PIGHV4-55*03X92263            |c237>a|                         |a263>c,Y88>S|
PIGHV4-55*04X92265 c44>t,P15>L|c237>a|
PIGHV4-55*05X92266 c44>t,P15>L|
PIGHV4-55*06X92267                                |c255>g,N85>K|            |c288>t|
PIGHV4-55*07X92268                   |a251>g,K84>R|            |a263>c,Y88>S|                   |g291>a|
PIGHV4-55*08X92234            |c237>a|                                                                 |t319>g|
PIGHV4-55*09X92235                                             |a263>c,Y88>S|      |c290>t,A97>V|      |t319>a|
IGHV4-59FIGHV4-59*01AB019438+g12  |g16  ,E6  |c20  ,S7  |c25  ,P9  |g37  |g51  ,E17  |a70  ,T24  |t76  ,c77  ,S26  |a88  ,I30  |c135  |c136  ,a138  ,P46  |a147  |t163  ,a164  ,t165  ,Y55  |t172  ,a173  ,c174  ,Y58  |a196  ,N66  |c207  |c228  |a234  ,I78  |a237  |c249  |g258  |c285  |t288  |g291  |c300  |g319  |a320  |
FIGHV4-59*02M29812                                                                                       |a88>g,I30>V|
FIGHV4-59*03M95114                                                                                                                                                                                                                                                 |g258>a|
FIGHV4-59*04M95117                                                                                                                                                                |             ,c174>t      |a196>t,N66>Y|c207>g|      |a234>g,I78>M|                           |t288>c|g291>a|c300>t|
FIGHV4-59*05M95118                                                                                                   |c135>g|      ,a138>g      |      |t163>c,a164>g,      ,Y55>R|             ,c174>t      |a196>t,N66>Y|c207>g|                   |a237>c|                    |t288>c|g291>a|c300>t|
FIGHV4-59*06M95119                                                                     |t76>a      ,S26>T|                  |c136>g,a138>t,P46>A|a147>c|             ,t165>c,     |                          |a196>t,N66>Y|c207>g|c228>t|                   |c249>t|      |c285>t|t288>c|
FIGHV4-59*07X56360                                             |g51>c,E17>D|                                                                                          
FIGHV4-59*08HM855471                                                                                                                                                                                                                                                               |t288>c|g291>a|g319>c|
FIGHV4-59*09Z75359                                                                                                                                                                                                                                                                                           |a320>g|
FIGHV4-59*10Z14243 g12>a|g16>c,E6>Q|c20>g,S7>W|c25>g,P9>A|g37>t|           |a70>g,T24>A|     ,c77>a,S26>Y|                  |c136>g,a138>c,P46>A|a147>g|t163>c,a164>g,      ,Y55>R|t172>a,a173>c,       Y58>T|                          |a234>g,I78>M|                           |t288>c|             |g319>t|
IGHV4-61FIGHV4-61*01M29811+g4  ,V2  |g48  |g49  ,E17  |g88  ,V30  |g97  ,G33  |a100  ,S34  |a118  ,S40  |c136  ,a138  ,P46  |g162  |t163  ,a164  ,Y55  |t172  ,a173  ,Y58  |c245  ,T82  |g258  ,Q86  |t288  |g289-g291         |g291  |g315  |g319  |
FIGHV4-61*02L10097          |g48>a|g49>c,E17>Q|g88>a,V30>I|                                     |c136>g,a138>c,P46>A|      |t163>c,a164>g,Y55>R|t172>a,a173>c,Y58>T|                         |t288>c|                  |g291>a|
FIGHV4-61*03X92230                                                                                                                                                              |g258>c,Q86>H|
FIGHV4-61*04X92250                                                                                                  |g162>a|                                                                        |g289-g291>del(3nt)|
FIGHV4-61*05X56356 g4>c,V2>L|                 |g88>a,V30>I|g97>a,G33>S|            |a118>g,S40>G|                                                                  |c245>a,T82>K|            |t288>c|
ORFIGHV4-61*06Z75347                                                                                                                                                                           |t288>c|                         |g315>c|
FIGHV4-61*07Z75348                                                                                                                                                                                                                   |g319>c|
FIGHV4-61*08AB019437                                                    |a100>g,S34>G|                                                                                                                                                             
IGHV4-bFIGHV4-b*01Z12367+g70  ,A24  |
FIGHV4-b*02X56365 g70>a,A24>T|
5IGHV5-51FIGHV5-51*01M99686+c45  |t116  ,I39  |g139  ,G47  |c148  |t247>c,S83  |
FIGHV5-51*02M18806      |t116>c,I39>T|            |c148>t|
FIGHV5-51*03X56368+c45>g|
FIGHV5-51*04X56367 c45>g|                                |t247>c,S83>P|
FIGHV5-51*05Z27449                   |g139>a,G47>R|
IGHV5-aFIGHV5-a*01X92227 t21  |c148  |c225  ,H75  |c288     ,A96     |
F(2)IGHV5-a*02X92279      |c148>t|            |c288>del#,A96>del#|
FIGHV5-a*03X56375 t21>c|
FIGHV5-a*04X56376             |c225>g,H75>Q|
6IGHV6-1FIGHV6-1*01J04097+a27  |
FIGHV6-1*02Z14223 a27>g|
7IGHV7-4-1FIGHV7-4-1*01L10057+t274  ,C92  |g278  ,c279  ,S93  |
FIGHV7-4-1*02X62110 t274>a,C92>S|
FIGHV7-4-1*03X92290 t274>a,C92>S|g278>c,c279>g,S93>T|
FIGHV7-4-1*04HM855485 |c257>t,T86>M| |t274>a,c92>S|
FIGHV7-4-1*05HM855361 |c257>t,T86>M| |t274>a,c92>S| |a305>g,Y102>C|
IGHV7-81ORFIGHV7-81*01AB019437+ 

(st):sterile transcript.

IMGT notes:
(1)Missing translation initiation codon, (atg) is replaced by (aag).
(2)The absence of nt in codon 96 in the sequence X92279 (c288>del compared with X92227) is a sequencing error because of an expressed cDNA (U00543) has been described. Therefore, the functionality of IGHV5-a*02 has been changed from pseudogene (P) to functional (F).


Created: 07/08/1997
Last updated: Monday, 06-Jun-2016 21:04:03 CEST
Authors: Joumana Jabado Michaloud, Nathalie Pallarès and Dominique Scaviner
Editor: Chantal Ginestoux

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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