IMGT Web resources: IMGT repertoire Table of alleles: Human TRAV

Print of this table: Scaviner, D. and Lefranc, M.-P., Exp. Clin. Immunogenet., 17, 83-96 (2000). PMID:10810225
UPDATE: 23/07/2003

Functionality is shown between:
- parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
- brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.
Nucleotide mutations and amino acid changes in CDR3-IMGT of rearranged sequences are not taken into account for the description of polymorphism.

Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).

TRAV subgroup TRAV 
gene name
Fct TRAV 
allele name
Accession number Confirmed 
by genetics
and/or data
Description of mutations
1 1-1 F V1-1*01 AE000658 + c170  ,A57  |
(F)
V1-1*02
X04939
+
c170>g,A57>G|
1-2 F V1-2*01 AE000658 + t196  |
[F] V1-2*02 U32544   t196>c|
2 2 F V2-1*01 AE000658 + t124  ,Y42  |
(F) V2-1*02 M17659   t124>c,Y42>H|
3 3 F V3*01 AE000658
+
c20     |
(P) V3*02 M27377   c20>del#|
4 4 F V4*01 AE000658
+
  
5 5 F V5*01 AE000659 +   
6 6 F V6*01 AE000659   a78  |c87  |c165  |a255  ,K85  |a271  ,I91  | 
(F) V6*02 X58747        |c87>t|
[F] V6*03 Z49060         |c87>t|c165>t| 
[F] V6*04 Y10409         |c87>t|                   |a271>g,I91>V|
[F] V6*05 Y10410   a78>g|c87>t|
[F] V6*06 U32542        |c87>t|      |a255>c,K85>N|
7 7 F V7*01 AE000659     
8 8-1 F V8-1*01 AE000659 + t235  ,F79  |
[F] V8-1*02 U32520   t235>g,F79>V|
8-2 F V8-2*01 AE000659   g22  ,a23  ,D8  |
(F) V8-2*02 M17650    g22>a,a23>g,D8>S|
8-3
F
V8-3*01
AE000659
  c204  |t264  |t297  |g298  ,A100  |
(F)
V8-3*02
M35617
        |t264>c|
(F)
V8-3*03
L06885
  c204>t|      |t297>g|g298>t,A100>S|
8-4
F
V8-4*01
AE000659
+
a45  |g46  ,G16  |c88  ,c89  ,P30  |t172  ,S58  |c176  ,A59  |c204  |g252  |g270  |t277  ,S93  |g290  ,S97  |g295  ,A99  | 
(F)
V8-4*02
M12423
                                                                             |g270>a| 
(F)
V8-4*03
D13077
  a45>g|                             |t172>a,S58>T|c176>g,A59>G|
(F)
V8-4*04
M12959
         |g46>c,G16>R|
(F)
V8-4*05
X63455
                                                               |c204>a| 
(F)
V8-4*06
K02777
                                                                                    |t277>g,S93>A| 
(F)
V8-4*07
M17665
                   |c88>g,c89>a,P30>E|t172>a,S58>T|c176>g,A59>G|      |g252>a|                   |g290>c,S97>T|g295>c,A99>P|
8-6
F
V8-6*01
X02850
+
g199  ,E67  |a202  ,S68  | 
F
V8-6*02
AE000659
  g199>a,E67>K|a202>g,S68>G| 
8-7
ORF
V8-7*01
AE000660
    
9 9-1 F V9-1*01 AE000659     
9-2
F
V9-2*01
AE000659
  a4  ,N2  |a252A  |
(F)
V9-2*02
X58745
  a4>g,N2>D| 
(F)
V9-2*03
L06881
  a4>g,N2>D|a252A>g|
(F)
V9-2*04
L06882
           |a252A>g|
10 10 F V10*01 AE000659 +   
11 11 P(11) V11*01 AE000659     
12 12-1
F
V12-1*01 AE000659 g246  ,Q82  |c247  ,L83  | 
(F)
V12-1*02
M17657
 
g246>c,Q82>H|c247>g,L83>V|
12-2
F
V12-2*01
AE000659
+
g86  ,G29  |t164  ,F55  | 
(F)
V12-2*02
M81774
+
           |t164>c,F55>S| 
(F)
V12-2*03
X04946
 
g86>t,G29>V|t164>c,F55>S|
12-3
F
V12-3*01
AE000659
+
a143  ,K48  | 
(F)
V12-3*02
M17656
  a143>t,K48>I| 
13 13-1
F
V13-1*01 AE000659 + g145  ,G49  |c270  ,H90  |   
(F)
V13-1*02
X04954
 
g145>a,G49>R|
[F]
V13-1*03
L11162
              |c270>g,H90>Q|
13-2
F
V13-2*01
AE000659
+
g129  | 
(F)
V13-2*02
M17658
  g129>a| 
14 14/DV4 F V14-1*01 M21626 + c89  ,P30  |a117  |c181  ,Q61  |c306  | 
F
V14-1*02
AE000659
  c89>a,P30>Q|      |c181>g,Q61>E|c306>t| 
(F)
V14-1*03
M21624
                                 |c306>t| 
[F]
V14-1*04
L09758
  c89>a,P30>Q|a117>c|c181>g,Q61>E|
16 16 F V16*01 AE000659 +   
17 17 F V17*01 AE000660 +   
18 18 F V18*01 AE000660       
19 19 F V19*01 AE000660 +   
20 20 F V20*01 AE000660   a55  ,S19  |t63  |a74  ,Y25  |   
(F)
V20*02
X68696
             |t63>c| 
(F)
V20*03
S60789
  a55>c,S19>R|t63>c|
(F)
V20*04
X70305
             |t63>c|a74>g,Y25>C| 
21 21 F V21*01 AE000660   g15  |
(F) V21*02 X58736   g15>a|
22 22 F V22*01 AE000660 +   
23 23/DV6 F V23*01 AE000660
+
t55  ,S19  |a129  |a132  | 
(F)
V23*02
M17660
+
t55>c,S19>P| 
(F)
V23*03
M97704
+
                  |a132>g|
[F]
V23*04
Y10411
             |a129>g|
24 24 F V24*01 AE000660 + a19  ,S7  |a141  ,g146  ,c147  ,S49  |c294  |
F V24*02 M17661 + a19>g,S7>G|a141>c|g146>c,c147>a,S49>T|c294>t|
25 25 F V25*01 AE000660 +    
26 26-1 F
V26-1*01
AE000660 + c25  ,P9  |t154  ,Y52  | 
(F)
V26-1*02
M27371
+
c25>a,P9>T| 
(F)
V26-1*03
L06886
            |t154>a,Y52>N|
26-2
F
V26-2*01
AE000660
+
c239  ,S80  |c241  ,L81  |
[F]
V26-2*02
L11160
  c239>g,S80>C|c241>g,L81>V|
27 27 F V27*01 AE000660  + a129  |a279  |c286  ,P96  |t302  ,L101  |   
(F)
V27*02
X04957
 
a129>g|a279>g|            |t302>a,L101>H|
(F)
V27*03
D13075
+
      |a279>g|c286>a,P96>T|t302>a,L101>H|
29 29/DV5 F V29*01 AE000660
+
c126     |c243  |g267  |c268  ,H90  |
(F) V29*02 S81645
 
         |c243>t|g267>c|c268>g,H90>D|
P
V29*03
AJ245565
 
c126>del#|c243>t|
30 30 F V30*01 AE000660 + t62  ,I21  |a200  ,K67  |g202  ,G68  |a206  ,H69  |a254  ,Q85  |
(F) V30*02 X58768    t62>c,I21>T|a200>t,K67>M|g202>c,G68>R|a206>g,H69>R| 
(F) V30*03 L06883                                                      |a254>g,Q85>R| 
[F]
V30*04
U32537
                          |g202>c,G68>R|
34 34 F V34*01 AE000660 +    
35 35 F V35*01 AE000660 + a135  ,E45  |   
(F)
V35*02
X58738
  a135>c,E45>D| 
36 36/DV7
F
V36*01
AE000660
  t26  ,L9  |c54  |t62  ,L21  |g79  ,V27  |t119  ,L40  |c257  ,S86  |a301  ,I101  | 
(F)
V36*02
X61070
  t26>a,L9>Q|c54>t|           |g79>a,V27>M|t119>a,L40>Q|c257>t,S86>F|a301>g,I101>V|
(F)
V36*03
X58767
            |c54>t|t62>c,L21>P|                        |c257>t,S86>F|a301>g,I101>V|
(F)
V36*04
Z46643
+
          |c54>t|                                    |c257>t,S86>F|a301>g,I101>V|
38 38-1
F
V38-1*01
AE000661
+
t21  |a24  |a89  ,N30 |a91  ,N31  |g129  |
(F)
V38-1*02
M64355
 
                      |a91>g,N31>D|
(F)
V38-1*03
M95394
             |a89>g,N30S|           |g129>a|
(F)
V38-1*04
L06880
  t21>c|a24>g|
38-2/DV8
F
V38-2*01
AE000661
+
  
39 39
F
V39*01
AE000661
+
  
40 40
F
V40*01
X73521
+
  
41 41
F
V41*01
AE000661
+
  

IMGT note:
(1) TRAV11 is pseudogene because there is no INIT-CODON in L-PART1 (atg replaced by acg).


Created: 11/06/98
Last updated: Friday, 27-May-2016 21:03:37 CEST
Author: Dominique Scaviner

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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