Table of alleles: Zebrafish (Danio rerio) IGHV

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

The IMGT allele table refers to the V-REGION polymorphism. It does not include polymorphisms in the other parts of the V-GENE. V-REGION alleles are only described for genes which have at least one Functional or ORF allele. The accession number of a reference sequence is given for each allele.

Click on a gene name to get the alignment of the corresponding V-REGION alleles.
Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).

Germline genomic sequences are needed to confirm if the nucleotide substitutions result from somatic mutations or correspond to allelic polymorphisms.

IGHV gene name Fct IGHV
allele name
Accession numbers Confirmed
Description of mutations
1 1S1 F V1S1*01 AF273897 + t60  |t89  ,M30  |c93  ,S31  |c96  |
(F) V1S1*02 AF273899   t60>a|t89>a,M30>K|c93>g,S31>R|c96>t|
1S2 (F) V1S2*01 AF273880   g95  ,S32  |t116  ,M39  |g139  ,G47  |g161  ,G54  |a166  ,t168  ,I56  |c183  |
(F) V1S2*02 AF273886                                                     |a166>t,t168>g,I56>L|
(F) V1S2*03 AF273889              |t116>c,M39>T|
(F) V1S2*04 AF273891                                                                         |c183>a|
(F) V1S2*05 AF273902   g95>c,S32>T|            |g139>a,G47>R|g161>t,G54>V| 
1S3 (F) V1S3*01 AF273890   c65  ,S22  |c71  ,T24  |t84  |g92  ,S31  |g96  ,R32  |c99  |t165  |t174  |g203  ,G68  |c243  ,D81  |
(F) V1S3*02 AF273900                          |t84>c|                             |t165>c|t174>c|            |c243>g,D81>E|
(F) V1S3*03 AF273901              |c71>t,T24>I|t84>c|           |g96>t,R32>S|                   |g203>c,G68>A|
(F) V1S3*04 AF273894 +                        |t84>c|g92>a,S31>N|           |c99>t|             |g203>c,G68>A|
(F) V1S3*05 AF273893   c65>a,S22>Y|           |t84>c|g92>a,S31>N|           |c99>t|             |g203>c,G68>A|
1S4 (F) V1S4*01 AF273892   g279  ,R93  |
(F) V1S4*02 AF273896   g279>c,R93>S|
2 2S1 (F) V2S1*01 AF273879 + g187  ,A63  |t279  ,S93  |
(F) V2S1*02 AF273887   g187>a,A63>T|t279>a,S93>R|
3 3S1 (F) V3S1*01 AF273883 +  
4 4S1 (F) V4S1*01 AF273876   c93  |t203  ,V68  |g227  ,G76  |a235  ,T79  |
(F) V4S1*02 AF273884                                  |a235>t,T79>S|
(F) V4S1*03 AF273877   c93>t|t203>c,V68>A|g227>c,G76>A|
4S2 (F) V4S2*01 AF273882   a15  |g244  ,D82  |
(F) V4S2*02 AF273885   a15>g|g244>a,D82>N|
4S3 (F) V4S3*01 AF273878    

Created: 15/11/2001
Author: Nathalie Bosc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc

CNRS Université de Montpellier European Commission
IMGT® Founder and Executive Director Emeritus:
Marie-Paule Lefranc
IMGT® Director:
Sofia Kossida
Bioinformatics manager:
Véronique Giudicelli
Computer manager:
Patrice Duroux
Amélie Houles

Citing IMGT | Warranty disclaimer and copyright notice | Privacy policy and advertisement policy

© Copyright 1995-2019 IMGT®, the international ImMunoGeneTics information system®