Assignment of rearranged cDNAs and gDNAs to germline genes: Human TRDV

In this table are listed the rearranged complementary DNAs (cDNAs) and genomic DNAs (gDNAs) which are quoted in Arden, B. et al., Immunogenetics, 42, 455-500 (1995), which represent potential new alleles without known germline sequences, or which have interesting characteristics.

Rearranged cDNAs (#c) and gDNAs (#g) TRDV sequences have been assigned to IMGT TRDV genes and alleles as described in Germline gene tables, Alignments of alleles and Tables of alleles. Assignments were performed using IMGT/V-QUEST.

References are presented chronologically whenever possible.

TRDV
gene name
Reference sequences Rearranged cDNAs and gDNAs CDR lengths JUNCTION (1)
Allele name Accession
number
Clone name Accession numbers
1 TRDV1*01 M22198 KT10E X14545 [5]#c [7.3.15] +
  M18414 [1]#c [7.3.24] +
D105 X15021 [3]#c [7.3.14] +
Pr81 X06557/Y00289 [2]#c [7.3.16] +
CTL55 AB164056 [9](2)#c [7.3.11] +
2 TRDV2*01 X15207 LB117 X13950 [6]#c [8.3.13] +
LB207 X13952 [6]#c [8.3.16] +
LB210 X13951 [6]#c [8.3.18] +
KT19E X14546 [5]#c [8.3.20] +
TRDV2*03 AE000661   X53849 [4]#c [8.3.16] +
  M21784 [7]#c [8.3.16] +
KT14E X14547 [5]#c [8.3.17] +
  X72501 [8]#c [8.3.16] +
3 TRDV3*01 M23326 KT041 X14544 [5]#c [7.5.21] +

#c: rearranged cDNA

IMGT notes:
(1) + indicates in-frame JUNCTION, - indicates out-of-frame JUNCTION, a blank indicates not defined.
(2) TRDV1*01 rearranged to TRAJ54*01. Another example of the TRDV1 gene being rearranged to a TRAJ gene was described in [10].
Comments added by M.-P. Lefranc on the 08/03/2003, based on information kindly provided by T. Ueno (Japan) on the 25/10/2002 and the CTL55 sequence submission to DDBJ on the 04/03/2003.

References:
[1] Hata, S. et al., Science, 238, 678-682 (1987).
[2] Loh, E.Y. et al., Nature, 330, 569-572 (1987).
[3] Okada, A. et al., J. Exp. Med., 168, 1481-1486 (1988).
[4] Triebel, F. et al., J. Immunol., 140, 300-304 (1988).
[5] Takihara, Y. et al., J. Exp. Med., 169, 393-405 (1989).
[6] Hata, S. et al., J. Exp. Med., 169, 41-57 (1989).
[7] Loh, E.Y. et al., Science, 243, 217-220 (1989).
[8] Davodeau, F., et al., J. Biol. Chem., 268, 15455-15460 (1993).
[9] Ueno, T. et al., Eur. J. Immunol., 33, 2910-2916 (2003) PMID:14515275
[10] Miossec, C. et al., J. Exp. Med., 171, 1171-1188 (1990) PMID:2182762


Created: 17/01/2001
Last updated: Friday, 27-May-2016 21:03:41 CEST
Authors: Géraldine Folch and Marie-Paule Lefranc

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