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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHA1 IGHA1*01 F Ig alpha-1 CH1 X53702 [1] X08041 [2] (2)
H+CH2 (1) X53702 [1] X08041 [2] (2)
CH3(including CHS) X53702 [1]
M
IGHA2 IGHA2*01 F Ig alpha-2 CH1 X53706 [1] X08040 [2] (2)
H+CH2 (1) X53706 [1] X08040 [2] (2)
CH3(including CHS) X53706 [1]
M
IGHE IGHE*01 F IgE CH1 M15398 [3]
CH2 M15398 [3]
CH3 M15398 [3]
CH4(including CHS) M15398 [3]
M1
M2
IGHG1 IGHG1*01 (F) IgG CH1 X65284 [4] c
H X65285 [4] c
CH2 X61311 [4] c
CH3(including CHS) X61310 [4] (3) c
M1
M2
IGHG1*02 F IGHG1 CH1 AF300437 [5] (2)
H AF300437 [5] (2)
CH2 AF300437 [5] (2)
CH3(including CHS)
M1
M2
IGHG2 IGHG2*01 F IGHG2 CH1 AF300436 [5] (2)
H AF300436 [5] (2)
CH2 AF300436 [5] (2)
CH3(including CHS)
M1
M2
IGHG3 IGHG3*01 F IGHG3 CH1 AF300434 [5] (2)
H1 AF300434 [5] (2)
H2 AF300434 [5] (2)
CH2 AF300434 [5] (2)
CH3(including CHS)
M1
M2
IGHG3*02 F IGHG3 CH1 AF300435 [5] (2)
H1 AF300435 [5] (2)
H2 AF300435 [5] (2)
CH2 AF300435 [5] (2)
CH3(including CHS)
M1
M2
IGHG4 IGHG4*01 F IGHG4 CH1 AF300432 [5] (2) AF300433 [5] (2)
H AF300432 [5] (2) AF300433 [5] (2)
CH2 AF300432 [5] (2) AF300433 [5] (2)
CH3(including CHS)
M1
M2
IGHGP IGHGP*01 F IGHGP CH1 AF300430 [5] (2)
H AF300430 [5] (2)
CH2 AF300430 [5] (2)
CH3(including CHS)
M1
M2
IGHGP*02 F IGHGP CH1 AF300431 [5] (2)
H AF300431 [5] (2)
CH2 AF300431 [5] (2)
CH3(including CHS)
M1
M2

c: cDNA sequence.

IMGT notes:
  1. (1) In the IGHA gene, the hinge (H) and CH2 are joined in a single exon.
  2. (2) Partial C-GENE: CH1 is partial in 5' and CH2 is partial in 3'.
  3. (3) Partial CH3 in 3'.
IMGT references:
  1. [1] Kawamura S. et al., J. Biol. Chem., 267, 7359-7367 (1992). PMID: 1559979
  2. [2] Ueda S. et al., J. Mol. Evol., 27, 77-83 (1988). PMID: 3133489
  3. [3] Sakoyama Y. et al., Proc. Natl. Acad. Sci. U.S.A., 84, 1080-1084 (1987). PMID: 3103123
  4. [4] Ehrlich P.H. et al., Mol. Immunol., 28, 319-322 (1991). PMID: 2062315
  5. [5] Fortenfant F. et al., Unpublished (2002).
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