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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct Allotypes T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHE IGHE*01 F a CH1 AJ305046 [1]
CH2 AJ305046 [1]
CH3 AJ305046 [1]
CH4(including CHS) AJ305046 [1]
IGHE*02 (F) CH1 U17041 [2] c (s)
CH2 U17041 [2] c (s)
CH3 U17041 [2] c (s)
CH4(including CHS) U17041 [2] c (s)
IGHE*03 (F) CH1 U15150 [3] c (s)
CH2 U15150 [3] c (s)
CH3 U15150 [3] c (s)
CH4(including CHS) U15150 [3] c (s)
IGHE*04 (F) b CH1 AJ305048 [1] c (s)
CH2 AJ305048 [1] c (s)
CH3 AJ305048 [1] c (s)
CH4(including CHS) AJ305048 [1] c (s)
IGHE*05 (F) CH3 L31502 [4] (1) c
CH4 L31502 [4] (1) c
IGHG1 IGHG1*01 F gamma-1 CH1 AJ302055 [5]
H AJ302055 [5]
CH2 AJ302055 [5]
CH3(including CHS) AJ302055 [5]
IGHG2 IGHG2*01 ORF (2) gamma-2 CH1 AJ302056 [5]
H AJ302056 [5]
CH2 AJ302056 [5]
CH3(including CHS) AJ302056 [5]
IGHG3 IGHG3*01 (F) gamma-3 CH1 AJ312379 [5] c (s)
H AJ312379 [5] c (s)
CH2 AJ312379 [5] c (s)
CH3(including CHS) AJ312379 [5] c (s)
IGHG4 IGHG4*01 F gamma-4 CH1 AJ302058 [5]
H AJ302058 [5]
CH2 AJ302058 [5]
CH3(including CHS) AJ302058 [5]
IGHG4*02 F gamma-4 CH1 AJ302057 [5]
H AJ302057 [5]
CH2 AJ302057 [5]
CH3(including CHS) AJ302057 [5]
IGHG5 IGHG5*01 F gamma-5 CH1 AJ312380 [5]
H AJ312380 [5]
CH2 AJ312380 [5]
CH3(including CHS) AJ312380 [5]
IGHG6 IGHG6*01 F gamma-6 CH1 AJ312381 [5]
H AJ312381 [5]
CH2 AJ312381 [5]
CH3(including CHS) AJ312381 [5]
IGHM IGHM*01 (F) CH1 L49414 [6] c (s)
CH2 L49414 [6] c (s)
CH3 L49414 [6] c (s)
CH4(including CHS) L49414 [6] c (s)

c: cDNA sequence.
(s): Transcript of a secreted chain.

IMGT notes:
  1. (1) Partial C-GENE: partial CH3 in 5' and partial CH4 in 3'
  2. (2) Non canonical ACCEPTOR-SPLICE: nacnn instead of nagnn.
IMGT references:
  1. [1] Wagner B. et al., Unpublished.
  2. [2] Watson J.L. et al., Unpublished.
  3. [3] Navarro P. et al., Mol. Immunol., 32, 1-8 (1995). PMID: 7870054
  4. [4] Marti E. et al., Vet. Immunol. Immunopathol., 47, 363-367 (1995). PMID: 8571554
  5. [5] Wagner B. et al., Immunobiology, 199, 105-118 (1998). PMID: 9717671
  6. [6] Schrenzel M.D. et al., Immunogenetics, 45, 386-393 (1997). PMID: 9089096
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Delphine Guiraudou
Chantal Ginestoux