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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT subgroup IMGT gene name IMGT allele name Fct R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHV1 IGHV1S1 IGHV1S1*01 (F) + + VHI AF437728 [1] #c
IGHV2 IGHV2S1 IGHV2S1*01 (F) + + VHII AF437724 [1] #c
IGHV3 IGHV3S1 IGHV3S1*01 (F) + + VHIII AF437725 [1] #c
IGHV4 IGHV4S1 IGHV4S1*01 (F) + + VHIV AF437729 [1] #c
IGHV5 IGHV5S1 IGHV5S1*01 (F) + + VHV AF437726 [1] (1) #c
AF437730 [1] (1) #c
IGHV6 IGHV6S1 IGHV6S1*01 (F) + + VHVI AF437731 [1] #c
IGHV7 IGHV7S1 IGHV7S1*01 (F) + + VHVII AF437727 [1] #c AF437733 [1] #c
AF437732 [1] #c
IGHV8 IGHV8S1 IGHV8S1*01 (F) + + VHVIII AF437734 [1] (2) #c

#c: rearranged cDNA

IMGT notes:
  1. (1) INSERTION of 1 amino acid between position 60 and 61 in CDR2-IMGT (60A).
  2. (2) The 2nd-CYS is not conserved (S at position 104 instead of C).
IMGT references:
  1. [1] Ota T. et al., Proc. Natl. Acad. Sci. U.S.A., 100, 2501-2506 (2003). PMID: 12606718
See also (IMGT Scientific chart):