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Citing this page: Bosc, N. and Lefranc, M.-P., Dev. Comp. Immunol., 27, 465-497 (2003) PMID: 12697305 UPDATE: 30/04/2003

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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In this table, are reported the 10 TRAV/DV genes identified so far:

If other TRAV genes or alleles are found rearranged to TRDJ genes, a suffix will be added to the gene name: /DV followed by a number for the TRDV subgroup (and eventually a hyphen and a gene number).

Clones used for the complete sequencing of the TRA/TRD locus (see IMGT/GeneView and Accession numbers of the Reference sequences) were later used to construct four contigs: AE008683 to AE008686.

In the TRA locus of Mus musculus C57BL/6J, there is an insertion of 300 kb between TRAV15D-3 and TRAV7-2, that corresponds to a triplication of part of the TRAV genes. The triplicated genes are indicated with the letter N in their name. They comprise 34 TRAV genes (of which 27 are functional and 7 are pseudogene).

The "invariant" TR alpha chain of the murine NK1.1+ (NKR-P1C, CD161) T cells which recognize CD1d results from the TRAV11-TRAJ18 (previously Valpha14-Jalpha281) rearrangement (it remains to be demonstrated if both the TRAV11 and TRAV11D genes, which have a 100 % identical V-REGION, are involved). CD161 is expressed by ~ 1 % of mouse T cells and a large fraction of these CD161+ T cells are invariant NK T cells [Exley, M.A. et al., Current Protocols in Immunology, Wiley, J. and Sons, New York, 14, 14.11.1-14.11.13 (2002)].

Click here for the Correspondence between nomenclatures.

IMGT subgroup IMGT gene name IMGT allele name Fct Chromosomal localization Alpha Delta Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
R T Pr R T Pr Strain Clone names Accession numbers Positions in the sequence (from INIT-CODON to the end of the V-REGION) Secondary accession numbers Strains Clone names Accession numbers Positions in the sequence (from INIT-CODON to the end of the V-REGION)
TRAV1 TRAV1 TRAV1*01 F 14 (19.7 cM) + + 129/SvJ TRAV1 MAP AF259072 [71] AE008683 [71] 72669-73602 (67)
TRAV1*02 (F) 14 (19.7 cM) + + B10.A (1) ValphaA10 MAP M22604 [17] #g
TRAV2 TRAV2 TRAV2*01 F 14 (19.7 cM) + + 129/SvJ TRAV2 MAP AF259071 [71] AF259074 [71]
AE008683 [71] 234790-235548 (67)
TRAV3 TRAV3-1 TRAV3-1*01 F 14 (19.7 cM) 129/SvJ TRAV3-1 MAP AF259071 [71] AE008683 [71] 246884-247390 (67)
TRAV3-1*02 (F) 14 (19.7 cM) + + C3H Valpha5 MAP AJ311366 [24] (48) #c
TRAV3-2 TRAV3-2*01 P (53) 14 (19.7 cM) 129/SvJ TRAV3-2P MAP AC003997 [71] AE008685 [71] 163451-163947 (67)
TRAV3D-2 TRAV3D-2*01 P (52) 14 (19.7 cM) 129/SvJ TRAV3D-2P MAP AC005402 [71] AE008684 [71] 136645-137116 (67)
TRAV3N-2 TRAV3N-2*01 P (65) 14 (19.7 cM) C57BL/6J AC188458 [79] 131414-131907 C57BL/6J AC161460 [79] 173049-172881
TRAV3-3 TRAV3-3*01 F 14 (19.7 cM) + + 129/SvJ TRAV3-3 MAP AC003997 [71] AE008685 [71] 261470-261971 (67)
TRAV3D-3 TRAV3D-3*01 F 14 (19.7 cM) 129/SvJ TRAV3D-3 MAP AC005402 [71] AE008684 [71] 223413-223914 (67)
TRAV3D-3*02 F 14 (19.7 cM) C57BL/6J AC163653 [79] 25037-25543
TRAV3N-3 TRAV3N-3*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 87454-87960 C57BL/6J AC122813 [79] 163680-164197
C57BL/Ka Valpha5 X02933 [3] #c
TRAV3-4 TRAV3-4*01 F 14 (19.7 cM) 129/SvJ TRAV3-4 MAP AC003996 [71] AE008685 [71] 380762-381263 (67)
AC005938 [71] 380762-381263 (67)
TRAV4 TRAV4-1 TRAV4-1*01 P (2) 14 (19.7 cM) 129/SvJ TRAV4-1P MAP AF259071 [71] AE008683 [71] 267059-267557 (67)
TRAV4-2 TRAV4-2*01 F 14 (19.7 cM) 129/SvJ TRAV4-2 MAP AC004407 [71] AE008684 [71] 366141-366627 (67)
TRAV4-2*02 F 14 (19.7 cM) + + C57BL/6 AC122813 [79] 82446-82931 C57BL/6 Valpha11 MAP M87848 [42] #c
TRAV4D-2 TRAV4D-2*01 P (3) 14 (19.7 cM) 129/SvJ TRAV4D-2P MAP AF259073 [71] AE008683 [71] 365129-365614 (67)
TRAV4-3 TRAV4-3*01 F 14 (19.7 cM) 129/SvJ TRAV4-3 MAP AC003997 [71] AE008685 [71] 175856-176358 (67)
TRAV4-3*02 (F) 14 (19.7 cM) + + BALB/c nu/nu V2B4 MAP M27351 [8] #c
TRAV4D-3 TRAV4D-3*01 F 14 (19.7 cM) + + 129/SvJ TRAV4D-3 MAP AC005402 [71] AE008684 [71] 149025-149526 (67)
TRAV4D-3*02 (F) 14 (19.7 cM) + + A/J Valpha11.3a M73265 [38] #c
TRAV4D-3*03 (F) 14 (19.7 cM) + + C57BL/6 Valpha11 MAP M87844 [42] #g
TRAV4D-3*04 (F) 14 (19.7 cM) + + Valpha11.3 S81113 [64] #c
TRAV4D-3*05 (F) 14 (19.7 cM) + + B10.A Valpha11 U63776 [65] (4) #g
TRAV4N-3 TRAV4N-3*01 F 14 (19.7 cM) + C57BL/6J AC188458 [79] 143795-144296 C57BL/6J AC161460 [79] 1054-1552
B10.A Valpha11 M22603 [17] #c
TRAV4-4/DV10 TRAV4-4/DV10*01 F 14 (19.7 cM) + + + + 129/SvJ TRADV4-4 MAP AC004102 [71] AE008685 [71] 278952-279455 (67)
TRAV4D-4 TRAV4D-4*01 F 14 (19.7 cM) + + 129/SvJ TRAV4D-4 MAP AC005855 [71] AE008684 [71] 241062-241562 (67)
TRAV4D-4*02 (F) 14 (19.7 cM) + + B10.A Valpha2B.4 MAP X02968 [4] #c
TRAV4D-4*03 F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 43391-43894 B10.A ValphaB10 MAP X03860 [7] #c
TRAV4D-4*04 (F) 14 (19.7 cM) + + DBA/2 Valpha11.1d M73264 [38] #c
TRAV4D-4*05 (F) 14 (19.7 cM) + + B10.A Valpha11 U63758 [65] (4) #g
TRAV4N-4 TRAV4N-4*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 69070-69570 C57BL/6J AC122813 [79] 198760-199260
TRAV5 TRAV5-1 TRAV5-1*01 F 14 (19.7 cM) + + 129/SvJ TRAV5-1 MAP AF259071 [71] AE008683 [71] 282342-282858 (67)
TRAV5-2 TRAV5-2*01 P (11) 14 (19.7 cM) 129/SvJ TRAV5-2P MAP AC003997 [71] AE008685 [71] 203144-203644 (67)
TRAV5D-2 TRAV5D-2*01 P (6) 14 (19.7 cM) 129/SvJ TRAV5D-2P MAP AC005402 [71] AE008684 [71] 163273-163788 (67)
TRAV5N-2 TRAV5N-2 P (66) 14 (19.7 cM) C57BL/6J AC188458 [79] 158291-158565 C57BL/6J AC161460 [79] (66) 145953-146227
TRAV5-3 TRAV5-3*01 P (12) 14 (19.7 cM) 129/SvJ TRAV5-3P MAP AC003997 [71] AE008685 [71] 217253-217574 (26)
TRAV5D-3 TRAV5D-3*01 P (7) 14 (19.7 cM) 129/SvJ TRAV5D-3P MAP AC005402 [71] AE008684 [71] 179278-179587 (26)
TRAV5N-3 TRAV5N-3*01 P (65) 14 (19.7 cM) C57BL/6J AC161460 [79] 132076-132345
TRAV5-4 TRAV5-4*01 ORF (8) 14 (19.7 cM) 129/SvJ TRAV5-4 MAP AC003995 [71] (8) AE008685 [71] 290091-290599 (67)
TRAV5D-4 TRAV5D-4*01 ORF (8) 14 (19.7 cM) + + 129/SvJ TRAV5D-4 MAP AC005855 [71] (8) AE008684 [71] 259064-259571 (67)
TRAV5D-4*02 (F) 14 (19.7 cM) + + SWR x NZB (F1) Valpha19 MAP U07877 [54] #c
TRAV5D-4*03 (F) 14 (19.7 cM) + + SWR x NZB (F1) Valpha19 MAP U07876 [54] (9) #c
TRAV5D-4*04 (F) 14 (19.7 cM) + + NOD U80816 [67] (10) #c
TRAV5D-4*05 F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 54218-54737
TRAV5N-4 TRAV5N-4*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 58486-58725 C57BL/6J AC122813 [79] 187897-188415
TRAV6 TRAV6-1 TRAV6-1*01 F 14 (19.7 cM) + + 129/SvJ TRAV6-1 MAP AF259071 [71] AE008683 [71] 298270-298714 (67)
TRAV6-1*02 (F) 14 (19.7 cM) + + C57BL/6 Valpha4 X14387 [27] #c
TRAV6-2 TRAV6-2*01 F 14 (19.7 cM) 129/SvJ TRAV6-2 MAP AF259071 [71] AE008683 [71] 321439-321892 (67)
TRAV6-2*02 (F) 14 (19.7 cM) + + C57BL/6 x DBA/2 (F1) ValphaII MAP X03669 [6] #g
TRAV6-2*03 (F) 14 (19.7 cM) + + BALB/c Valpha4.2 U21455 [57] (14) #c
TRAV6-3 TRAV6-3*01 F 14 (19.7 cM) + + 129/SvJ TRAV6-3 MAP AC004407 [71] AE008684 [71] 381244-382887 (67)
TRAV6-3*02 F 14 (19.7 cM) + + C57BL/6J AC122813 [79] 70942-72558
TRAV6D-3 TRAV6D-3*01 F 14 (19.7 cM) + + 129/SvJ TRAV6D-3 MAP AF259073 [71] AE008683 [71] 380537-382152 (67)
AC005403 [71] 380537-382152 (67)
TRAV6D-3*02 (F) 14 (19.7 cM) + + C57BL/6 Valpha4 MAP M16675 [11] #c
TRAV6-4 TRAV6-4*01 F 14 (19.7 cM) + + 129/SvJ TRAV6-4 MAP AC004407 [71] AE008685 [71] 8045-8502 (67)
TRAV6-4*02 (F) 14 (19.7 cM) + + BALB/c Valpha4 M84653 [44] #c
TRAV6-4*03 F 14 (19.7 cM) C57BL/6J AC122813 [79] 46535-46992
TRAV6D-4 TRAV6D-4*01 F 14 (19.7 cM) 129/SvJ TRAV6D-4 MAP AC005403 [71] AE008684 [71] 4732-5180 (67)
TRAV6-5 TRAV6-5*01 F 14 (19.7 cM) + + 129/SvJ TRAV6-5 MAP AC004405 [71] AE008685 [71] 55987-56459 (67)
TRAV6-5*02 (F) 14 (19.7 cM) + + BALB/c Valpha4 M34202 [32] (16) #c
TRAV6-5*03 (F) 14 (19.7 cM) + + BALB/cJ Valpha4 U05046 [66] (18) #c
TRAV6-5*04 F 14 (19.7 cM) C57BL/6J AC122813 [79] 9697-10167
TRAV6D-5 TRAV6D-5*01 F 14 (19.7 cM) + + 129/SvJ TRAV6D-5 MAP AC003994 [71] AE008684 [71] 39554-40024 (67)
TRAV6N-5 TRAV6N-5*01 F 14 (19.7 cM) C57BL/6J AC163653 [79] 157376-157849 C57BL/6J AC188458 [79] 37754-37802
TRAV6-6 TRAV6-6*01 F 14 (19.7 cM) + + 129/SvJ TRAV6-6 MAP AC005240 [71] AE008685 [71] 87550-87987 (67)
TRAV6-6*02 (F) 14 (19.7 cM) + + BALB/c Valpha4.6 U21448 [57] (18) #c
TRAV6-6*03 (F) 14 (19.7 cM) + + C57BL/6 Valpha4.5 U90513 [68] (10) #c
TRAV6D-6 TRAV6D-6*01 F 14 (19.7 cM) + + 129/SvJ TRAV6D-6 MAP AC004101 [71] AE008684 [71] 64381-64818 (67)
TRAV6D-6*02 F 14 (19.7 cM) + + C57BL/6 Valpha112-2 MAP X05187 [13] (15)
TRAV6D-6*03 (F) 14 (19.7 cM) + + C57BL/10 Valpha4 MAP M16676 [11] #c
TRAV6D-6*04 (F) 14 (19.7 cM) + + BALB/c Valpha4 U21397 [58] (16) #c
TRAV6D-6*05 (F) 14 (19.7 cM) + + B10.M TCRAV4S13 AY665736 [78] (60) #c B10.M TCRAV4S13 AY665730 [78] (60) #c
TRAV6N-6 TRAV6N-6*01 F 14 (19.7 cM) + + AC163653 [79] 185205-185642 C57BL/6J AC188458 [79] 65583-66020
TRAV6-7/DV9 TRAV6-7/DV9*01 F 14 (19.7 cM) + + 129/SvJ TRAV6-7 MAP AC003995 [71] AE008685 [71] 295983-296449 (67)
TRAV6-7/DV9*02 (F) 14 (19.7 cM) + + C57BL/Ka Valpha4 MAP X02932 [3] #c
TRAV6-7/DV9*03 (F) 14 (19.7 cM) + + B10.PL Valpha4.2 MAP M21863 [22] #c
TRAV6-7/DV9*04 (F) 14 (19.7 cM) + + C57BL/6 Vdelta2.3 MAP X13316 [18] (19) #c
TRAV6-7/DV9*05 (P) (20) 14 (19.7 cM) B10.PL Valpha4.2 M35492 [28] #c
TRAV6-7/DV9*06 (F) 14 (19.7 cM) + + BALB/c Valpha4 U21453 [57] (16) #c
TRAV6-7/DV9*07 (F) 14 (19.7 cM) + + BALB/c Valpha4 U21409 [58] (21) #c
TRAV6-7/DV9*08 (F) 14 (19.7 cM) + + BALB/c x C57BL/6 (F1) Valpha4 MAP D12899 [49] (24) #c
TRAV6D-7 TRAV6D-7*01 F 14 (19.7 cM) 129/SvJ TRAV6D-7 MAP AC005855 [71] AE008684 [71] 264948-265414 (67)
TRAV6D-7*02 (F) 14 (19.7 cM) + + PL x SJL (F1) Valpha4 MAP M21205 [16] #c
TRAV6D-7*03 (F) 14 (19.7 cM) + + DBA/2 Valpha4 X55823 [35] (17) #c
TRAV6D-7*04 F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 60137-60603
TRAV6N-7 TRAV6N-7*01 F 14 (19.7 cM) AC161460 [79] 52345-52811 C57BL/6J AC122813 [79] 182035-182501
C57BL/10 Valpha4 X52448 [36] #c
TRAV7 TRAV7-1 TRAV7-1*01 F 14 (19.7 cM) + + 129/SvJ TRAV7-1 MAP AF259071 [71] AE008683 [71] 313424-313940 (67)
TRAV7-2 TRAV7-2*01 F 14 (19.7 cM) 129/SvJ TRAV7-2 MAP AC004407 [71] AE008684 [71] 341683-342196 (67)
TRAV7-2*02 F 14 (19.7 cM) C57BL/6J AC122813 [79] 110176-110684
TRAV7D-2 TRAV7D-2*01 F 14 (19.7 cM) 129/SvJ TRAV7D-2 MAP AF259071 [71] AE008683 [71] 337968-338476 (67)
TRAV7D-2*02 (F) 14 (19.7 cM) + + B10.A Valpha1 MAP M38104 [34] #g
TRAV7D-2*03 (F) 14 (19.7 cM) + + BALB/c Valpha1 X83009 [59] (22) #c
TRAV7-3 TRAV7-3*01 F 14 (19.7 cM) + + 129/SvJ TRAV7-3 MAP AC004407 [71] AE008684 [71] 394979-395504 (67)
TRAV7-3*02 (F) 14 (19.7 cM) + + BALB/c Valpha1 MAP L16803 [53] (24) #c
TRAV7-3*03 (F) 14 (19.7 cM) + + SJL Valpha1 MAP AF037038 [72] #c
TRAV7-3*04 F 14 (19.7 cM) + + C57BL/6J AC122813 [79] 57480-58005
TRAV7D-3 TRAV7D-3*01 F 14 (19.7 cM) + + C57BL/10 Valpha5H MAP X02833 [2] 129/SvJ TRAV7D-3 MAP AC005403 [71]
TRAV7D-3 MAP AE008683 [71] 399727-400523 (67)
TRAV7D-3*02 (F) 14 (19.7 cM) + + B10.A x AKR Valpha11 MAP M26423 [29] (23) #c
TRAV7-4 TRAV7-4*01 F 14 (19.7 cM) + + 129/SvJ TRAV7-4 MAP AC004407 [71] AE008685 [71] 14951-15840 (67)
TRAV7-4*02 F 14 (19.7 cM) + + C57BL/6J AC122813 [79] 39581-40110
TRAV7D-4 TRAV7D-4*01 F 14 (19.7 cM) + + C57BL/6 Valpha1.1 MAP X56723 [37]
TRAV7D-4*02 F 14 (19.7 cM) + + 129/SvJ TRAV7D-4 MAP AC003994 [71] AE008684 [71] 14121-14650 (67)
TRAV7D-4*03 (F) 14 (19.7 cM) + + C57BL/Ka Valpha1 MAP X02928 [3] #c
TRAV7N-4 TRAV7N-4*01 F 14 (19.7 cM) C57BL/6J AC163653 [79] 143851-144380 C57BL/6J AC188458 [79] 24229-24758
C57BL/6 Valpha1.1 X56722 [37] #c
TRAV7-5 TRAV7-5*01 F 14 (19.7 cM) + + 129/SvJ TRAV7-5 MAP AC004406 [71] AE008685 [71] 107905-108432 (67)
TRAV7-5*02 (F) 14 (19.7 cM) + + DBA/2 Valpha1 X55825 [35] (25) #c
TRAV7-5*03 (F) 14 (19.7 cM) + + C57BL/6 Valpha1 AF034160 [69] (24) #c
TRAV7D-5 TRAV7D-5*01 F 14 (19.7 cM) 129/SvJ TRAV7D-5 MAP AC004101 [71] AE008684 [71] 84720-85247 (67)
TRAV7N-5 TRAV7N-5*01 F 14 (19.7 cM) C57BL/6J AC163653 [79] 199427-199953 C57BL/6J AC188458 [79] 79811-80337
C57BL/6 Valpha1.2 X56724 [37] (25)
TRAV7-6 TRAV7-6*01 F 14 (19.7 cM) 129/SvJ TRAV7-6 MAP AC003995 [71] AE008685 [71] 302286-302818 (67)
TRAV7-6*02 (F) 14 (19.7 cM) + + C57BL/6 ValphaC5 MAP X63927 [4] #c
TRAV7D-6 TRAV7D-6*01 F 14 (19.7 cM) 129/SvJ TRAV7D-6 MAP AC005855 [71] AE008684 [71] 271489-272021 (67)
TRAV7D-6*02 F 14 (19.7 cM) C57BL/6J AC163653 [79] 72964-73496
TRAV7N-6 TRAV7N-6*01 F 14 (19.7 cM) AC161460 [79] 46421-46953 C57BL/6J AC122813 [79] 176111-176643
TRAV8 TRAV8-1 TRAV8-1*01 F (28) 14 (19.7 cM) + + 129/SvJ TRAV8-1 MAP AC004407 [71] (28) AE008685 [71] 23478-23963 (67)
AC004405 [71] 23478-23963 (67)
TRAV8-1*02 (F) 14 (19.7 cM) + + C57BL/10 D16605 [50] (29) #c
TRAV8-1*03 F 14 (19.7 cM) + + C57BL/6J AC122813 [79] 31087-31563
TRAV8D-1 TRAV8D-1*01 F 14 (19.7 cM) + + 129/SvJ TRAV8D-1 MAP AC003994 [71] AE008684 [71] 22759-23244 (67)
TRAV8D-1*02 (F) 14 (19.7 cM) + + C57BL/10 X06773 [9] (16) #c
TRAV8-2 TRAV8-2*01 F 14 (19.7 cM) 129/SvJ TRAV8-2 MAP AC004096 [71] AE008685 [71] 323696-324159 (67)
TRAV8D-2 TRAV8D-2*01 F 14 (19.7 cM) 129/SvJ TRAV8D-2 MAP AC005855 [71] AE008684 [71] 293412-293875 (67)
TRAV8D-2*02 (F) 14 (19.7 cM) + + B10.BR Valpha18 MAP U46581 [45] #c
TRAV8D-2*03 F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 94933-95396
TRAV8N-2 TRAV8N-2*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 25205-25668 C57BL/6J AC122813 [79] 154895-155358
TRAV9 TRAV9-1 TRAV9-1*01 F 14 (19.7 cM) 129/SvJ TRAV9-1 MAP AC004405 [71] AE008685 [71] 53147-53608 (67)
TRAV9-1*02 F 14 (19.7 cM) C57BL/6J AC122813 [79] 12752-13213
TRAV9D-1 TRAV9D-1*01 F 14 (19.7 cM) + + 129/SvJ TRAV9D-1 MAP AC003994 [71] AE008684 [71] 36514-36975 (67)
TRAV9D-1*02 (F) 14 (19.7 cM) + + C57BL/6 Valpha3 MAP M16678 [11] #c
TRAV9N-1 TRAV9N-1 P (63) 14 (19.7 cM) C57BL/6J AC163653 [79] 154306-154770 C57BL/6J AC188458 [79] 34684-34729
TRAV9-2 TRAV9-2*01 F 14 (19.7 cM) + + BALB/c Tcra-V3.1 MAP U26917 [62] 129/SvJ TRAV9-2 MAP AC003997 [71]
TRAV9-2 MAP AE008685 [71] 168052-168486 (67)
TRAV9D-2 TRAV9D-2*01 F 14 (19.7 cM) BALB/c Tcra-V3.2 MAP U31877 [62]
TRAV9D-2*02 F 14 (19.7 cM) 129/SvJ TRAV9D-2 MAP AC005402 [71] AE008684 [71] 141221-141655 (67)
TRAV9D-2*03 (F) (13) 14 (19.7 cM) BALB/c Valpha3 M33586 [33] (13) #c
TRAV9D-2*04 (P) (30) 14 (19.7 cM) BALB/c Valpha3 MAP L16799 [53] (30) #c
TRAV9N-2 TRAV9N-2 F 14 (19.7 cM) C57BL/6J AC188458 [79] 136011-136443 C57BL/6J AC161460 [79] 168462-168357
TRAV9-3 TRAV9-3*01 F 14 (19.7 cM) + + BALB/c Tcra-V3.3 MAP U31878 [62] 129/SvJ TRAV9-3 MAP AC003997 [71]
TRAV9-3 MAP AE008685 [71] 209671-210105 (67)
TRAV9-3*02 (F) 14 (19.7 cM) + + BALB/c Valpha3 M34194 [32] (10) #c
TRAV9-3*03 (F) 14 (19.7 cM) + + BALB/cJ Valpha3.4 U05047 [66] (32) #c
TRAV9D-3 TRAV9D-3*01 F 14 (19.7 cM) + + 129/SvJ TRAV9D-3 MAP AC005402 [71] AE008684 [71] 169749-170183 (67)
TRAV9D-3*02 (F) 14 (19.7 cM) + + C57BL/10 Valpha3.810 MAP X05732 [10] #c
TRAV9N-3 TRAV9N-3*01 F 14 (19.7 cM) + + C57BL/6J AC188458 [79] 164557-164991 C57BL/6J AC161460 [79] 139916-139809
C57BL/6 Valpha3.C9 X05734 [10] #c
TRAV9-4 TRAV9-4*01 F 14 (19.7 cM) + + BALB/c X02857 [1] BALB/c Tcra-V3.4 MAP U31879 [62]
129/SvJ TRAV9-4 MAP AC003997 [71]
AE008685 [71] 271478-271912 (67)
TRAV9D-4 TRAV9D-4*01 F 14 (19.7 cM) + + 129/SvJ TRAV9D-4 MAP AC005855 [71] AE008684 [71] 233384-233818 (67)
TRAV9D-4*02 P (61) 14 (19.7 cM) + + C57BL/6J AC163653 [79] 35961-36365
TRAV9D-4*03 (F) 14 (19.7 cM) + + C57BL/6 Valpha3 MAP X56716 [37] (31) #c
TRAV9D-4*04 (F) 14 (19.7 cM) + + C57BL/6 Valpha3 MAP M87852 [42] #c
TRAV9N-4 TRAV9N-4*01 F 14 (19.7 cM) AC161460 [79] 76599-77033 C57BL/6J AC122813 [79] 206289-206723
TRAV10 TRAV10 TRAV10*01 F (33) 14 (19.7 cM) + + 129/SvJ TRAV10 MAP AC005240 [71] (33) SJL/J SJL-HE-1.1 X57397 (59) #c
AE008685 [71] 76501-76997 (67)
TRAV10*02 (F) 14 (19.7 cM) + + C57BL/6 Valpha15 L34678 [60] #c
TRAV10*03 (F) 14 (19.7 cM) + + C57BL/6 Tcra-V22.1 U47051 [63] #c
TRAV10*04 (P) (34) 14 (19.7 cM) C57BL/6 Tcra-V22.3 U46078 [63] #g
TRAV10*05 (P) (34) 14 (19.7 cM) C57BL/6 Tcra-V22.4 U46079 [63] #g
TRAV10D TRAV10D*01 F (33) 14 (19.7 cM) + + 129/SvJ TRAV10D MAP AC003994 [71] (33) AE008684 [71] 53958-54454 (67)
AC004101 [71]
TRAV10D*02 (P) (34) 14 (19.7 cM) C57BL/6 Tcra-22.2 U46077 [63] #g
TRAV10N TRAV10N*01 F 14 (19.7 cM) C57BL/6 AC163653 [79] 174619-175115 C57BL/6J AC188458 [79] 54997-55493
TRAV11 (49) TRAV11 TRAV11*01 F (35) 14 (19.7 cM) + + 129/SvJ TRAV11 MAP AC005240 [71] (35) B10.A-Tcrac TRAV11*01 AY158220 [77] (57)
NOD TRAV11*01 AY158221 [77] (57) #c
C57BL/6 Valpha14.2 D90230 [39] (36)
AE008685 [71] 89958-90510 (67)
TRAV11*02 F (57) 14 (19.7 cM) + + B10.A TRAV11*02 AY158218 [77] (57) C57BL/6 Valpha14.1 D90229 [39] (36)
TRAV11D TRAV11D*01 F (35) 14 (19.7 cM) + + 129/SvJ TRAV11D MAP AC004101 [71] (35) AE008684 [71] 66780-67332 (67)
TRAV11N TRAV11N*01 P (64) 14 (19.7 cM) + + C57BL/6J AC163653 [79] 187627-188183 C57BL/6J AC188458 [79] 68005-68561
B10.A TRAV11*03 AY158219 [77] (58)
TRAV12 TRAV12-1 TRAV12-1*01 F 14 (19.7 cM) C57BL/6 ValphaF3.5 MAP X06307 [5]
TRAV12-1*02 F 14 (19.7 cM) Std:ddY Valpha8 MAP X17173 [20]
TRAV12-1*03 ORF (38) 14 (19.7 cM) 129/SvJ TRAV12-1 MAP AC004406 [71] (38) AE008685 [71] 125175-125647 (67)
TRAV12-1*04 (F) 14 (19.7 cM) + + C57BL/6 Valpha8 MAP M16677 [11] #c
TRAV12-1*05 (F) 14 (19.7 cM) + + C57BL/Ka Valpha8.4 MAP M38680 [21] #c
TRAV12D-1 TRAV12D-1*01 F 14 (19.7 cM) C57BL/6 ValphaF3.6 MAP X06308 [5]
TRAV12D-1*02 F 14 (19.7 cM) + + 129/SvJ TRAV12D-1 MAP AC004101 [71] AE008684 [71] 92193-92665 (67)
TRAV12D-1*03 (F) 14 (19.7 cM) + + C57BL/Ka Valpha8 MAP X02936 [3] (37) #c
TRAV12D-1*04 (F) 14 (19.7 cM) + + C57BL/6 Valpha8 MAP X60320 [41] #g
TRAV12D-1*05 (F) 14 (19.7 cM) + + C57BL/6 ValphaF3.8 U90515 [68] (10) #c
TRAV12N-1 TRAV12N-1*01 F 14 (19.7 cM) + + C57BL/6J AC188458 [79] 88490-88977
TRAV12-2 TRAV12-2*01 F 14 (19.7 cM) + + 129/SvJ TRAV12-2 MAP AC003997 [71] AE008685 [71] 204854-205387 (67)
TRAV12D-2 TRAV12D-2*01 F 14 (19.7 cM) + + C57BL/6 ValphaF3.2 MAP X04332 [5]
TRAV12D-2*02 F 14 (19.7 cM) + + 129/SvJ TRAV12D-2 MAP AC005402 [71] AE008684 [71] 164976-165491 (67)
TRAV12D-2*03 (F) 14 (19.7 cM) + + C57BL/6 ValphaF3.2 MAP X04330 [5] #c
TRAV12D-2*04 (F) 14 (19.7 cM) + + BALB/c M15063 [14] #c
TRAV12D-2*05 (F) 14 (19.7 cM) + + BALB/c Valpha8 M98569 [46] (16) #c
TRAV12N-2 TRAV12N-2*01 F 14 (19.7 cM) C57BL/6J AC188458 [79] 159778-160289 C57BL/6J AC161460 [79] 144229-144509
ValphaF3.4 MAP X06306 [5]
TRAV12-3 TRAV12-3*01 F 14 (19.7 cM) + + 129/SvJ TRAV12-3 MAP AC003997 [71] AE008685 [71] 218750-219243 (67)
TRAV12-3*02 (F) 14 (19.7 cM) + + Std:ddY Valpha8 MAP X17181 [20] #g
TRAV12-3*03 (F) 14 (19.7 cM) + + DBA/2 Valpha8 X67432 [40] #g
TRAV12-3*04 (F) 14 (19.7 cM) + + BALB/c Valpha8 U21399 [58] (19) #c
TRAV12D-3 TRAV12D-3*01 (ORF) (50) 14 (19.7 cM) + + C57BL/6 ValphaF3.7 U90514 [68] (50) #c
TRAV12D-3*02 F 14 (19.7 cM) 129/SvJ TRAV12D-3 MAP AC005402 [71] AE008684 [71] 180766-181258 (67)
TRAV12D-3*03 (F) 14 (19.7 cM) + + BALB/c Valpha8 M34210 [32] (10) #c
TRAV12N-3 TRAV12N-3*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 130385-130883 C57BL/6 ValphaF3.3 MAP X06305 [5]
TRAV12-4 TRAV12-4*01 P (39) 14 (19.7 cM) 129/SvJ TRAV12-4P MAP AC005938 [71] AE008685 [71] 382085-382499 (26)
TRAV12-4*02 P (40) 14 (19.7 cM) C57BL/6 ValphaF3.1psi MAP X06309 [5]
TRAV13 TRAV13-1 TRAV13-1*01 F 14 (19.7 cM) + + 129/SvJ TRAV13-1 MAP AC004406 [71] AE008685 [71] 131957-132468 (67)
TRAV13D-1 TRAV13D-1*01 F 14 (19.7 cM) + + 129/SvJ TRAV13D-1 MAP AC005402 [71] AE008684 [71] 99029-99540 (67)
TRAV13D-1*02 (F) 14 (19.7 cM) + + B10.S/9R Valpha10.2 MAP M20875 [19] #c
TRAV13D-1*03 (F) 14 (19.7 cM) + + BALB/c Valpha10 M34216 [32] (31) #c
TRAV13N-1 TRAV13N-1*01 F 14 (19.7 cM) + + C57BL/6J AC188458 [79] 95288-95799
TRAV13-2 TRAV13-2*01 F 14 (19.7 cM) 129/SvJ TRAV13-2 MAP AC003997 [71] AE008685 [71] 231729-232240 (67)
TRAV13-2*02 (F) 14 (19.7 cM) + + B10.A Valpha10 MAP M38102 [34] #g
TRAV13D-2 TRAV13D-2*01 F 14 (19.7 cM) + + Std:ddY Valpha10 MAP X17178 [20] 129/SvJ TRAV13D-2 MAP AC005402 [71]
AE008684 [71] 193728-194239 (67)
TRAV13D-2*02 (F) 14 (19.7 cM) + + BALB/c Valpha10 U21415 [58] (41) #c
TRAV13N-2 TRAV13N-2*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 117319-117837
TRAV13-3 TRAV13-3*01 F 14 (19.7 cM) 129/SvJ TRAV13-3 MAP AC003995 [71] AE008685 [71] 314684-315198 (67)
AC004096 [71]
TRAV13-3*02 ORF (42) 14 (19.7 cM) Std:ddY Valpha10 MAP X17176 [20] (42)
TRAV13D-3 TRAV13D-3*01 F 14 (19.7 cM) 129/SvJ TRAV13D-3 MAP AC005855 [71] AE008684 [71] 284816-285330 (67)
TRAV13D-3*02 F 14 (19.7 cM) C57BL/6J AC163653 [79] 85407-85924
TRAV13N-3 TRAV13N-3*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 33990-34507 C57BL/6J AC122813 [79] 163680-164197
TRAV13-4/DV7 TRAV13-4/DV7*01 F 14 (19.7 cM) + + 129/SvJ TRADV13-4 MAP AC003996 [71] AE008685 [71] 354062-354573 (67)
TRAV13-4/DV7*02 (F) 14 (19.7 cM) + + C57BL/6 Vdelta7 MAP M26299 [25] #c
TRAV13-4/DV7*03 (F) 14 (19.7 cM) + + SWR x NZB (F1) Valpha10 MAP U07879 [54] #c
TRAV13D-4 TRAV13D-4*01 F 14 (19.7 cM) 129/SvJ TRAV13D-4 MAP AC005855 [71] AE008684 [71] 314380-316122 (67)
AC004407 [71]
TRAV13D-4*02 (F) 14 (19.7 cM) + + B10.S/9R Valpha10.3 MAP M20876 [19] #c
TRAV13D-4*03 F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 125268-125779 C57BL/6J AC188458 [79] 5646-6157
TRAV13N-4 TRAV13N-4*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 7523-7793 C57BL/6J AC122813 [79] 137213-138951
TRAV13-5 TRAV13-5*01 F 14 (19.7 cM) 129/SvJ TRAV13-5 MAP AC005938 [71] AE008686 [71] 2674-3182 (67)
TRAV14 TRAV14-1 TRAV14-1*01 F 14 (19.7 cM) + + B10.A Tcra-V2.3 L77150 [61]
TRAV14-1*02 F 14 (19.7 cM) BALB/c Tcra-V2.2 MAP U04622 [52] 129/SvJ TRAV14-1 MAP AC004406 [71]
AE008685 [71] 136454-136955 (67)
TRAV14-1*03 (F) 14 (19.7 cM) + + BALB/c Valpha2.2 MAP AJ311368 [26] (10,48) #c
TRAV14D-1 TRAV14D-1*01 F 14 (19.7 cM) + + B10.A Tcra-V2.2 L77149 [61]
TRAV14D-1*02 ORF (43) 14 (19.7 cM) + + BALB/c Tcra-V2.3 MAP U04623 [52] (43) 129/SvJ TRAV14D-1 MAP AC005402 [71] (43)
TRAV14D-1 MAP AE008684 [71] (43) 108054-108555 (67)
TRAV14N-1 TRAV14N-1*01 F 14 (19.7 cM) + + C57BL/6J AC188458 [79] 99566-100067 C57BL/6J AC161460 [79] 204896-204725
TRAV14-2 TRAV14-2*01 F 14 (19.7 cM) + + B10.A Tcra-V2.1 L77148 [61]
TRAV14-2*02 F 14 (19.7 cM) + + B10.A Tcra-V2.6 L77153 [61]
TRAV14-2*03 F 14 (19.7 cM) + + BALB/c Tcra-V2.5 MAP U04625 [52] 129/SvJ TRAV14-2 MAP AC003997 [71]
TRAV14-2 MAP AE008685 [71] 237700-238201 (67)
TRAV14D-2 TRAV14D-2*01 F (51) 14 (19.7 cM) + + BALB/c Tcra-V2.1 MAP U04312 [52] (51) 129/SvJ TRAV14D-2 MAP AC005402 [71] (51)
TRAV14D-2 MAP AE008684 [71] (51) 199520-200019 (67)
TRAV14D-2*02 (F) 14 (19.7 cM) + + CBA/J Valpha2 M88352 [47] (44) #c
TRAV14D-2*03 F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 1119-1620
TRAV14N-2 TRAV14N-2*01 F 14 (19.7 cM) C57BL/6J AC161460 [79] 111411-111729
TRAV14-3 TRAV14-3*01 (68) F 14 (19.7 cM) + + B10.A Tcra-V2.7 L77154 [61]
TRAV14-3*02 F 14 (19.7 cM) + + BALB/c Tcra-V2.6 MAP U04626 [52] 129/SvJ TRAV14-3 MAP AC003996 [71]
TRAV14-3 MAP AE008685 [71] 359846-360344 (67)
TRAV14-3*03 (F) 14 (19.7 cM) + + C56BL/6 x DBA/2 (F1) TCRAV2 AF126459 [73] #c
TRAV14D-3/DV8 TRAV14D-3/DV8*01 (69) F 14 (19.7 cM) + + B10.A Tcra-V2.5 L77152 [61]
TRAV14D-3/DV8*02 F 14 (19.7 cM) + + B10.A Tcra-V2.4 L77151 [61]
TRAV14D-3/DV8*03 F 14 (19.7 cM) + + BALB/c Tcra-V2.4 MAP U04624 [52] 129/SvJ TRADV14D-3 MAP AC004407 [71]
TRADV14D-3 MAP AE008684 [71] 322095-322593 (67)
TRAV14D-3/DV8*04 (F) 14 (19.7 cM) + + C57BL/10 Vdelta8 U07557 [26] (19) #c
TRAV14D-3/DV8*05 (F) 14 (19.7 cM) + + SWR x NZB (F1) Valpha2 MAP U07872 [54] #c
TRAV14D-3/DV8*06 (F) 14 (19.7 cM) + + SWR x NZB (F1) Valpha2 MAP U07875 [54] #c
TRAV14D-3/DV8*07 (F) 14 (19.7 cM) + + C57BL/6 x DBA/2 (F1) TCRAV2 AF126457 [73] #c
TRAV14D-3/DV8*08 (68) F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 131052-131550 C57BL/6J AC188458 [79]
TRAV14N-3 TRAV14N-3*01 (69) F 14 (19.7 cM) C57BL/6J AC161460 [79] 1054-1552 C57BL/6J AC122813 [79] 130744-131242
TRAV15 TRAV15-1/DV6-1 TRAV15-1/DV6-1*01 F 14 (19.7 cM) + + + + 129/SvJ TRADV15-1 MAP AC004406 [71] AE008685 [71] 142067-142638 (67)
TRAV15-1/DV6-1*02 (F) 14 (19.7 cM) + + BALB/c Vdelta2 MAP X63939 [15] #c
TRAV15D-1/DV6D-1 TRAV15D-1/DV6D-1*01 F 14 (19.7 cM) BALB/c delta1 MAP X07878 [23]
TRAV15D-1/DV6D-1*02 F 14 (19.7 cM) + + 129/SvJ TRADV15D-1 MAP AC005402 [71] AE008684 [71] 113676-114247 (67)
TRAV15D-1/DV6D-1*03 (F) 14 (19.7 cM) + + C57BL/6 Vdelta1 X17225 [30] #g
TRAV15D-1/DV6D-1*04 (F) 14 (19.7 cM) + + DBA/2 Vdelta6.4 U66666 [70] (10) #c
TRAV15D-1/DV6D-1*05 (F) 14 (19.7 cM) + + DBA/2 Vdelta6.5 U66667 [70] (10) #c
TRAV15D-1/DV6D-1*06 (F) 14 (19.7 cM) + + DBA/2 Vdelta6.6 U66668 [70] (10) #c
TRAV15N-1 TRAV15N-1*01 F 14 (19.7 cM) + + C57BL/6J AC188458 [79] 107214-107785 C57BL/6J AC161460 [79] 197256-197024
C57BL/Ka Valpha7 X02935 [3] #c
TRAV15-2/DV6-2 TRAV15-2/DV6-2*01 F 14 (19.7 cM) + + 129/SvJ TRDV15-2 MAP AC003997 [71] AE008685 [71] 245725-246294 (67)
TRAV15-2/DV6-2*02 (F) 14 (19.7 cM) + + C57BL/6 Vdelta6 AF085010 [43] (56) #c
TRAV15D-2/DV6D-2 TRAV15D-2/DV6D-2*01 F 14 (19.7 cM) + + 129/SvJ TRADV15D-2 MAP AC005402 [71] AE008684 [71] 207686-208258 (67)
TRAV15D-2/DV6D-2*02 (F) 14 (19.7 cM) + + B10.A AJ271435 [76] #c
TRAV15D-2/DV6D-2*03 (70) F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 9333-9905 C57BL/6 Vdelta6 AF085009 [43] (56) #c
TRAV15D-2/DV6D-2*04 (F) 14 (19.7 cM) + + DBA/2 Vdelta6 AF085006 [43] (56) #c
TRAV15D-2/DV6D-2*05 (F) 14 (19.7 cM) + + DBA/2 Vdelta6 AF085008 [43] (56) #c
TRAV15N-2 TRAV15N-2*01 (70) F 14 (19.7 cM) C57BL/6J AC161460 [79] 103094-103666
TRAV15-3 TRAV15-3*01 P (54) 14 (19.7 cM) 129/SvJ TRAV15-3P MAP AC003996 [71] AE008685 [71] 363363-363768 (67)
TRAV15D-3 TRAV15D-3*01 P (54) 14 (19.7 cM) 129/SvJ TRAV15D-3P MAP AC004407 [71] AE008684 [71] 326032-326403 (67)
TRAV15D-3*02 P (62) 14 (19.7 cM) C57BL/6J AC163653 [79] 134568-135029 C57BL/6J AC188458 [79] 14946-15407
TRAV15N-3 TRAV15N-3*01 P (65) 14 (19.7 cM) + + C57BL/6J AC122813 [79] 126040-126498
TRAV16 TRAV16 TRAV16*01 (71) F 14 (19.7 cM) + + 129/SvJ TRAV16 MAP AC004096 [71] AE008685 [71] 328553-329084 (67)
TRAV16*02 (F) 14 (19.7 cM) + + SWRxNZB(F1) Valpha16 MAP U07873 [54] #c
TRAV16*03 (F) 14 (19.7 cM) + + NOD S69341 [55] #c
TRAV16*04 (F) 14 (19.7 cM) + + CBA S73533 [56] #c
TRAV16*05 (F) 14 (19.7 cM) + + C57BL/6xDBA/2 Valpha17 MAP AF118105 [74] (32) #c
TRAV16D/DV11 TRAV16D/DV11*01 F 14 (19.7 cM) + + 129/SvJ TRADV16D MAP AC005855 [71] AE008684 [71] 298506-299037 (67)
TRAV16D/DV11*02 (71) F 14 (19.7 cM) + + C57BL/6J AC163653 [79] 99792-100326
TRAV16D/DV11*03 (F) 14 (19.7 cM) + + + + C57BL/6 M16119 [12] #c
TRAV16N TRAV16N*01 F 14 (19.7 cM) + + C57BL/6J AC161460 [79] 20010-20539 C57BL/6J AC122813 [79] 149698-150229
C57BL/6 M16118 [12] #c
TRAV17 TRAV17 TRAV17*01 F 14 (19.7 cM) + + 129/SvJ TRAV17 MAP AC005938 [71] AE008686 [71] 18507-18983 (67)
TRAV17*02 (F) 14 (19.7 cM) + + C57BL/6 X60319 [41] #g
TRAV18 TRAV18 TRAV18*01 ORF (8) 14 (19.7 cM) 129/SvJ TRAV18 MAP AC005938 [71] AE008686 [71] 51750-52475 (67)
TRAV19 TRAV19 TRAV19*01 F (45) 14 (19.7 cM) + + 129/SvJ TRAV19 MAP AE008686 [71] (45) 74507-75012 (67) BALB/c Valpha5T X72906 [48] (45)(10)
Valpha5T AC005938 [71]
TRAV19*02 P (46) 14 (19.7 cM) BALB/c Valpha5Tpsi X72903 [48]
TRAV19*03 (F) 14 (19.7 cM) + + C57BL/6 AV20S1 AF171639 [75] #c
TRAV20 TRAV20 TRAV20*01 P (47) 14 (19.7 cM) BALB/c Valpha16.1 MAP M94080 [51] 129/SvJ TRAV20P MAP AC005938 [71] (47)
TRAV20P MAP AE008686 [71] (47) 92619-93170 (67)
TRAV20*02 (P) (47) 14 (19.7 cM) AKR M29272 [31] #c
TRAV21 TRAV21/DV12 TRAV21/DV12*01 F 14 (19.7 cM) + + BALB/c Vdelta3 MAP M94080 [51] 129/SvJ TRADV21 MAP AC005938 [71]
TRADV21 MAP AE008686 [71] 106852-107590 (67)
TRAV21/DV12*02 (F) 14 (19.7 cM) + + C57BL/Ka Valpha6 MAP X02934 [3] #c
TRAV22 TRAV22 TRAV22*01 P (27) 14 (19.7 cM) 129/SvJ TRAV22P MAP AC004399 [71] AE008686 [71] 165091-165399 (26)
TRAV23 TRAV23 TRAV23*01 P (55) 14 (19.7 cM) 129/SvJ TRAV23P MAP AC003993 [71] AE008686 [71] 195682-196206 (67)

#c: rearranged cDNA
#g: rearranged genomic DNA.
MAP: mapped sequences.

IMGT notes:
  1. (1) B10.A is a congenic strain (see MGD for Strain Nomenclature Guidelines), B10 is the abbreviated symbol of C57BL/10.
  2. (2) In frame STOP-CODON at codon 6 in FR1-IMGT (positions 16-18 in IMGT unique numbering), INSERTION of 1 nucleotide c in FR1-IMGT (between positions 54 and 55), DELETION of 2 nucleotides in FR3-IMGT (positions 221-222).
  3. (3) In frame STOP-CODON at codon 83 in FR3-IMGT (positions 247-249 in IMGT unique numbering).
  4. (4) INSERTION of 12 nucleotides CCCAGCTGGAGG in FR3-IMGT (between positions 293 and 294 in IMGT unique numbering). This INSERTION is a duplication of positions 280-293 (Bosc, N., IMGT comment, 01/02/2001) and may represent a sequencing error.
  5. (5) INIT-CODON not conserved in L-PART1: ATC instead of ATG.
  6. (6) In frame STOP-CODONs at codon 58 in CDR2-IMGT (positions 172-174 in IMGT unique numbering), at codons 99 and 104 in FR3-IMGT (positions 295-297 and 310-312), the 2nd-CYS is not conserved.
  7. (7) No L-PART1, in frame STOP-CODON at codon 5 in FR1-IMGT (positions 13-15 in IMGT unique numbering) and DELETION of 1 nucleotide in FR1-IMGT (position 42), DELETION of 6 nucleotides in frame (positions 229-234) and of 16 nucleotides in FR3-IMGT (position 262-277), STOP-CODON at codon 99 in FR3-IMGT (positions 295-297).
  8. (8) ORF because unusual V-HEPTAMER sequence: CACACTG instead of CACAGTG.
  9. (9) V-REGION is partial: AA 1 to 22 are missing (partial FR1-IMGT).
  10. (10) V-REGION is partial: AA 1 is missing (partial FR1-IMGT).
  11. (11) In frame STOP-CODONs at codon 58 in CDR2-IMGT (positions 172-174 in IMGT unique numbering) and at codon 99 in FR3-IMGT (positions 295-297).
  12. (12) No L-PART1, in frame STOP-CODON at codon 5 in FR1-IMGT (positions 13-15 in IMGT unique numbering) and DELETION of 1 nucleotide in FR1-IMGT (position 42) , DELETION of 6 nucleotides in frame (positions 229-234) and of 4 nucleotides in FR3-IMGT (positions 281-284), STOP-CODON at codon 99 in FR3-IMGT (positions 295-297).
  13. (13) Sterile transcript
  14. (14) V-REGION is partial: AA 1 to 15 are missing (partial FR1-IMGT).
  15. (15) V-GENE is partial: partial V-SPACER and no V-NONAMER.
  16. (16) V-REGION is partial: AA 1 to 10 are missing (partial FR1-IMGT).
  17. (17) V-REGION is partial: AA 1 to 25 are missing (partial FR1-IMGT).
  18. (18) V-REGION is partial: AA 1 to 8 are missing (partial FR1-IMGT).
  19. (19) V-REGION is partial: AA 1 to 9 are missing (partial FR1-IMGT).
  20. (20) DELETION of 1 nucleotide in CDR2-IMGT (position 83 in IMGT unique numbering).
  21. (21) V-REGION is partial: AA 1 to 11 are missing (partial FR1-IMGT).
  22. (22) V-REGION is partial: AA 1 to 69 are missing (no FR1-IMGT, no CDR1-IMGT, no FR2-IMGT, no CDR2-IMGT, partial FR3-IMGT).
  23. (23) V-REGION is partial: AA 1 to 19 are missing (partial FR1-IMGT).
  24. (24) V-REGION is partial: AA 1 to 44 are missing (no FR1-IMGT, no CDR1-IMGT, partial FR2-IMGT).
  25. (25) V-REGION is partial: AA 1 to 51 are missing (no FR1-IMGT, no CDR1-IMGT and partial FR2-IMGT).
  26. (26) No L-PART1, limits are from the first nucleotide to the last nucleotide of V-EXON.
  27. (27) No L-PART1 and frameshifts in V-REGION..
  28. (28) Although the V-HEPTAMER is unusual (CACAGTA instead of CACAGTG), the gene has been found rearranged and is therefore functional.
  29. (29) V-REGION is partial: AA 1 to 56 are missing (no FR1-IMGT, no CDR1-IMGT, no FR2-IMGT and partial CDR2-IMGT).
  30. (30) DELETION of 1 nucleotide in FR3-IMGT (position 299 in IMGT unique numbering). V-REGION is partial: AA 1 to 43 are missing (no FR1-IMGT, no CDR1-IMGT and partial FR2-IMGT).
  31. (31) V-REGION is partial: AA 1 to 38 are missing (no FR1-IMGT, no CDR1-IMGT and no FR2-IMGT).
  32. (32) V-REGION is partial: AA 1 and 2 are missing (partial FR1-IMGT).
  33. (33) Although the V-HEPTAMER is unusual (CACACTG instead of CACAGTG), the gene has been found rearranged and is therefore functional.
  34. (34) INSERTION of 1 nucleotide leads to a frameshift in L-PART1.
  35. (35) Although the V-HEPTAMER is unusual (CACCATG instead of CACAGTG), the gene has been found rearranged and is therefore functional.
  36. (36) V-REGION is partial: AA 1 and 2, 106 and 107 are missing (partial FR1-IMGT and partial CDR3-IMGT). It is not known if this sequence is an allele of TRAV11 or of TRAV11D (see note (49)).
  37. (37) V-REGION is partial: AA 1 to 42 are missing (no FR1-IMGT, no CDR1-IMGT and partial FR3-IMGT), DELETION of 3 nucleotides in frame in FR3-IMGT (positions 279-281 in IMGT unique numbering, S93 is encoded by TCG instead of TCA) .
  38. (38) ORF because unusual V-HEPTAMER sequence: CACAGCG instead of CACAGTG.
  39. (39) No L-PART1, V-REGION is partial: AA 1 to 3 are missing (partial FR1-IMGT), in frame STOP-CODONs at codon 40 in FR2-IMGT (positions 118-120 in IMGT unique numbering) and at codon 91 in FR3-IMGT (positions 271-273), DELETION of 9 nucleotides in FR3-IMGT (positions 296-304) leading to a frameshift.
  40. (40) V-REGION is partial: AA 1 to 4 are missing (partial FR1-IMGT), in frame STOP-CODON at codon 40 (positions 118-120 in IMGT unique numbering) and DELETION of 1 nucleotide in FR2-IMGT (position 149).
  41. (41) V-REGION is partial: AA 1 to 17 are missing (partial FR1-IMGT).
  42. (42) ORF because unusual V-HEPTAMER sequence: GAGGGTG instead of CACAGTG.
  43. (43) ORF because no CONSERVED-TRP
  44. (44) V-REGION is partial: AA 1 to 27 are missing (no FR1-IMGT and partial CDR1-IMGT).
  45. (45) Although the V-HEPTAMER is unusual (CACGGTA instead of CACAGTG), the gene has been found rearranged and therefore is functional.
  46. (46) In frame STOP-CODON at codon 2 in FR1-IMGT (positions 4-6 in IMGT unique numbering), DELETION of 11 nucleotides in FR3-IMGT (positions 262-272) , STOP-CODON at codon 104 in FR3-IMGT (positions 310-312).
  47. (47) In frame STOP-CODONs at codons 4 and 11 in FR1-IMGT (positions 10-12 and 31-33 in IMGT unique numbering).
  48. (48) Sequence submitted to EMBL by IMGT curators (Bosc, N., 21/04/2001).
  49. (49) For the TRAV11 subgroup, sequences of the TRAV11D gene cannot be differentiated from those of the TRAV11 gene, when these sequences are not mapped. These unmapped sequences are therefore described as "TRAV11 alleles" and compared to the allele *01 of TRAV11 (AC005240). However it is not excluded that some of these "alleles" belong exclusively to the TRAV11D gene.
  50. (50) ORF because the 1st-CYS is not conserved, V-REGION is partial: AA 1 is missing (partial FR1-IMGT).
  51. (51) U04312 and AC005402 have the same V-REGION but L-PART1 and L-PART2 are different.
  52. (52) DELETION of 12 nucleotides in CDR1-IMGT (positions 85-96 in IMGT unique numbering), in frame STOP-CODON at codon 43 in FR2-IMGT (positions 127-129) and INSERTION of 6 nucleotides in CDR2-IMGT (between positions 169/170).
  53. (53) INIT-CODON not conserved in L-PART1: AAG instead of ATG, DELETION of 12 nucleotides in CDR1-IMGT (positions 85-96 in IMGT unique numbering), in frame STOP-CODON at codon 43 in FR2-IMGT (positions 127-129) and INSERTION of 6 nucleotides in CDR2-IMGT (between positions 169/170), no CONSERVED-TRP.
  54. (54) DELETION 1 nucleotide in FR1-IMGT (position 32 in IMGT unique numbering), no CONSERVED-TRP, and V-REGION is partial: AA 43 to 90 are missing (partial FR2-IMGT, no CDR2-IMGT and partial FR3-IMGT).
  55. (55) INSERTION of 13 nucleotides in FR3-IMGT (between positions 281/282 in IMGT unique numbering).
  56. (56) V-GENE is partial (no L-PART1, no L-PART2), and V-REGION is partial: AA 1 is absent (FR1-IMGT is partial).
  57. (57) It is not known if this sequence is an allele of TRAV11 or of TRAV11D (see note (49)).
  58. (58) In frame STOP-CODON at codon 25 in FR1-IMGT (positions 73-75 in IMGT unique numbering). It is not known if this sequence is an allele of TRAV11 or of TRAV11D (see note (49)).
  59. (59) X53732 differs by one undefined nucleotide at codon 7 (position 20 in IMGT unique numbering).
  60. (60) Potentiel allele base on the finding of several sequences in cDNA (IMGT Annotation: Yan Wu, Géraldine Folch, Marie-Paule Lefranc 19/01/2009).
  61. (61) 10 AA missing in CDR2-IMGT and FR3-IMGT.
  62. (62) Frameshift in V-REGION, Some amino acids are deleted in FR1-IMGT and FR3-IMGT.
  63. (63) Frameshift in FR3-IMGT.
  64. (64) STOP-CODON in frame in FR1-IMGT.
  65. (65) Frameshift in V-REGION.
  66. (66) No L-PART1, in frame STOP-CODON in V-REGION.
  67. (67) Limits from INIT-CODON (ATG) to the last nucleotide of V-REGION in the following Accession numbers: AE008683, AE008684, AE008685 and AE008686.
  68. (68) The V-REGION of allele TRAV14-3*01 is 100% identical to the V-REGION of allele TRAV14D-3/DV8*08.
  69. (69) The V-REGION of allele TRAV14D-3/DV8*01 is 100% identical to the V-REGION of allele TRAV14N-3*01.
  70. (70) The V-REGION of allele TRAV15D-2/DV6D-2*03 is 100% identical to the V-REGION of allele TRAV15N-2*01.
  71. (71) The V-REGION of allele TRAV16*01 is 100% identical to the V-REGION of allele TRAV16D/DV11*02.
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See also (IMGT Scientific chart):