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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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cDNAs have been included in this table as they are informative for the gene content of the corresponding genomic cassettes. M1 and M2 exons are not shown if not yet isolated.

Two types of cassettes are identified for IGHN.
Type 1 is characterized by the V-GENE having a Cys 40 and the J-GENE having a Cys 118.
Type 2 is characterized by the V-GENE having an amino acid other than Cys in 40 (for example: Y, S, R in Nurse shark) and the J-GENE having an amino acid other than Cys in 118 (for example Y in Nurse shark).

Cassette Cassette type Clone name Gene name Accession numbers
1 2 G11 IGHV2S1 L38965
IGHD1
IGHD2
IGHD3
IGHJ1
IGHN
2 2 JIIR11 IGHV2S2 L38966
IGHD4
IGHD5
IGHJ2
IGHN
3 2 JIIR5 IGHV2S3 L38967
IGHD6
IGHD7
IGHD8
IGHJ3
IGHN
4 1 JIIRB5 IGHV2S4 L38968
IGHD9
IGHD10
IGHD11
IGHJ4
IGHN
5 #c nd IGHV1S1 M92851
IGHD12
IGHJ5
IGHM1
6 #c nd IGHV1S2 AF327520
IGHD13
IGHJ6
IGHM2
7 #c 1 3-4 IGHV2S26 U18701
IGHD14
IGHJ7
IGHN1
8 #c 2 1.3 IGHV2S5 U18680
IGHD15
IGHJ8
IGHN2
9 #c 2 5A IGHV2S41 U18716
IGHD16
IGHJ9
IGHN3
10 #c 1 5Fs IGHV2S42 U18717
IGHD17
IGHJ10
IGHN4
11 #c 2 1A IGHV2S11 U18686
IGHD18
IGHJ11
IGHN5
12 #c 1 1C IGHV2S12 U18687
IGHD19
IGHJ12
IGHN6
13 #c 2 4Fs IGHV2S39 U18714
IGHD20
IGHJ13
IGHN7
14 #c 1 5H IGHV2S43 U18718
IGHD21
IGHJ14
IGHN8
15 #c 2 4.1 IGHV2S38 U18713
IGHD22
IGHJ15
IGHN9
16 #c 1 3-10 IGHV2S25 U18700
IGHD23
IGHJ16
IGHN10
17 #c 1 3-9 IGHV2S27 U18702
IGHD24
IGHJ17
IGHN11
18 #c 1 4J IGHV2S40 U18715
IGHD25
IGHJ18
IGHN12
19 #c 2 1N IGHV2S51 U18726
IGHD26
IGHJ19
IGHN13
20 (1) #c 1 2D IGHV2S18 U18693
IGHD27
IGHJ20
IGHN14
21 #c 1 5D IGHV2S50 U18725
IGHD28
IGHJ21
IGHN15
22 #c 1 12P IGHV2S10 U18685
IGHD29
IGHJ22
IGHN16
23 #c 2 1I IGHV2S13 U18688
IGHD30
IGHJ23
IGHN17
24 #c 1 9K IGHV2S49 U18724
IGHD31
IGHJ24
IGHN18
25 #c 1 2K IGHV2S21 U18696
IGHD32
IGHJ25
IGHN19
26 #c 1 3H1 IGHV2S30 U18705
IGHD33
IGHJ26
IGHN20
27 #c 1 3G IGHV2S28 U18703
IGHD34
IGHJ27
IGHN21
28 #c 1 12A IGHV2S7 U18682
IGHD35
IGHJ28
IGHN22
29 #c 1 3L IGHV2S31 U18706
IGHD36
IGHJ29
IGHN23
30 #c 1 3G1 IGHV2S29 U18704
IGHD37
IGHJ30
IGHN24
31 #c 1 10N IGHV2S6 U18681
IGHD38
IGHJ31
IGHN25
32 #c 1 12K IGHV2S9 U18684
IGHD39
IGHJ32
IGHN26
33 #c 1 3N IGHV2S33 U18708
IGHD40
IGHJ33
IGHN27
34 #c 1 7B IGHV2S47 U18722
IGHD41
IGHJ34
IGHN28
35 #c 1 12J IGHV2S8 U18683
IGHD42
IGHJ35
IGHN29
36 #c 1 1NDs IGHV2S15 U18690
IGHD43
IGHJ36
IGHN30
37 #c 1 2H IGHV2S20 U18695
IGHD44
IGHJ37
IGHN31
38 #c 1 3S IGHV2S37 U18712
IGHD45
IGHJ38
IGHN32
39 #c 1 5NB IGHV2S44 U18719
IGHD46
IGHJ39
IGHN33
40 #c 2 2A IGHV2S16 U18691
IGHD47
IGHJ40
IGHN34
41 #c 1 2E IGHV2S19 U18694
IGHD48
IGHJ41
IGHN35
42 #c 1 5NC IGHV2S45 U18720
IGHD49
IGHJ42
IGHN36
43 #c 1 2P IGHV2S23 U18698
IGHD50
IGHJ43
IGHN37
44 #c 1 2As IGHV2S17 U18692
IGHD51
IGHJ44
IGHN38
45 #c 1 3M IGHV2S32 U18707
IGHD52
IGHJ45
IGHN39
46 #c 1 2T IGHV2S24 U18699
IGHD53
IGHJ46
IGHN40
47 #c 1 3NG IGHV2S35 U18710
IGHD54
IGHJ47
IGHN41
48 #c 1 1Is IGHV2S14 U18689
IGHD55
IGHJ48
IGHN42
49 #c 1 3NB IGHV2S34 U18709
IGHD56
IGHJ49
IGHN43
50 #c nd IGHV1S3 U51450
IGHD57
IGHJ50
IGHW1
51 #c 1 2L IGHV2S22 U18697
IGHD58
IGHJ51
52 #c 1 9F IGHV2S48 U18723
IGHD59
IGHJ52
53 (2) #c 1 7A IGHV2S46 U18721

#c: rearranged cDNA.

IMGT notes:
  1. (1) It is not excluded that the C < V amino acid change is due to a typing error by inversion of two nucleotides.
  2. (2) Sequence is partial: No J-GENE. V-GENE having a Cys 40, this cassette is assigned to type 1.
See also (IMGT Scientific chart):