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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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M1 and M2 exons are not shown if not yet isolated.

IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHM1 IGHM1*01 F CH1 M92851 [1] c(s)
CH2 M92851 [1] c(s)
CH3 M92851 [1] c(s)
CH4 (including CHS) M92851 [1] c(s)
IGHM2 IGHM2*01 F (2) IGM1gj CH1 AF327520 [2] c(s)
CH3 AF327520 [2] c(s)
CH4 AF327520 [2] c(s)
CH5 (including CHS) AF327520 [2] c(s)
IGHN1 IGHN1*01 CH1 U18701 [3] c(s)
CH2 U18701 [3] c(s)
CH3 U18701 [3] c(s)
CH4 U18701 [3] c(s)
CH5 (including CHS) U18701 [3] c(s)
IGHN2 IGHN2*01 F 1.3 CH1 U18680 [3] (1) c
CH2 U18680 [3] (1) c
1.3 CH3
CH4
CH5
IGHN3 IGHN3*01 F 5A CH1 U18716 [3] (1) c
CH2 U18716 [3] (1) c
5A CH3
CH4
CH5
IGHN4 IGHN4*01 F 5Fs CH1 U18717 [3] (1) c
CH2 U18717 [3] (1) c
5Fs CH3
CH4
CH5
IGHN5 IGHN5*01 F 1A CH1 U18686 [3] (1) c
CH2 U18686 [3] (1) c
1A CH3
CH4
CH5
IGHN6 IGHN6*01 F 1C CH1 U18687 [3] (1) c
CH2 U18687 [3] (1) c
1C CH3
CH4
CH5
IGHN7 IGHN7*01 F 4Fs CH1 U18714 [3] (1) c
CH2 U18714 [3] (1) c
4Fs CH3
CH4
CH5
IGHN8 IGHN8*01 F 5H CH1 U18718 [3] (1) c
CH2 U18718 [3] (1) c
5H CH3
CH4
CH5
IGHN9 IGHN9*01 F 4.1 CH1 U18713 [3] (1) c
CH2 U18713 [3] (1) c
4.1 CH3
CH4
CH5
IGHN10 IGHN10*01 F 3-10 CH1 U18700 [3] (1) c
CH2 U18700 [3] (1) c
3-10 CH3
CH4
CH5
IGHN11 IGHN11*01 F 3-4 CH1 U18702 [3] (1) c
CH2 U18702 [3] (1) c
3-4 CH3
CH4
CH5
IGHN12 IGHN12*01 F 3-9 CH1 U18715 [3] (1) c
CH2 U18715 [3] (1) c
3-9 CH3
CH4
CH5
IGHN13 IGHN13*01 F 4J CH1 U18726 [3] (1) c
CH2 U18726 [3] (1) c
4J CH3
CH4
CH5
IGHN14 IGHN14*01 F 2D CH1 U18693 [3] (1) c
CH2 U18693 [3] (1) c
2D CH3
CH4
CH5
IGHN15 IGHN15*01 F 5D CH1 U18725 [3] (1) c
CH2 U18725 [3] (1) c
5D CH3
CH4
CH5
IGHN16 IGHN16*01 F 12P CH1 U18685 [3] (1) c
12P CH2
CH3
CH4
CH5
IGHN17 IGHN17*01 F 1I CH1 U18688 [3] (1) c
1I CH2
CH3
CH4
CH5
IGHN18 IGHN18*01 F 9K CH1 U18724 [3] (1) c
9K CH2
CH3
CH4
CH5
IGHN19 IGHN19*01 F 2K CH1 U18696 [3] (1) c
2K CH2
CH3
CH4
CH5
IGHN20 IGHN20*01 F 3H1 CH1 U18705 [3] (1) c
3H1 CH2
CH3
CH4
CH5
IGHN21 IGHN21*01 F 3G CH1 U18703 [3] (1) c
3G CH2
CH3
CH4
CH5
IGHN22 IGHN22*01 F 12A CH1 U18682 [3] (1) c
12A CH2
CH3
CH4
CH5
IGHN23 IGHN23*01 F 3L CH1 U18706 [3] (1) c
3L CH2
CH3
CH4
CH5
IGHN24 IGHN24*01 F 3G1 CH1 U18704 [3] (1) c
3G1 CH2
CH3
CH4
CH5
IGHN25 IGHN25*01 F 10N CH1 U18681 [3] (1) c
10N CH2
CH3
CH4
CH5
IGHN26 IGHN26*01 F 12K CH1 U18684 [3] (1) c
12K CH2
CH3
CH4
CH5
IGHN27 IGHN27*01 F 3N CH1 U18708 [3] (1) c
3N CH2
CH3
CH4
CH5
IGHN28 IGHN28*01 F 7B CH1 U18722 [3] (1) c
7B CH2
CH3
CH4
CH5
IGHN29 IGHN29*01 F 12J CH1 U18683 [3] (1) c
12J CH2
CH3
CH4
CH5
IGHN30 IGHN30*01 F 1NDs CH1 U18690 [3] (1) c
1NDs CH2
CH3
CH4
CH5
IGHN31 IGHN31*01 F 2H CH1 U18695 [3] (1) c
2H CH2
CH3
CH4
CH5
IGHN32 IGHN32*01 F 3S CH1 U18712 [3] (1) c
3S CH2
CH3
CH4
CH5
IGHN33 IGHN33*01 F 5NB CH1 U18719 [3] (1) c
5NB CH2
CH3
CH4
CH5
IGHN34 IGHN34*01 F 2A CH1 U18691 [3] (1) c
2A CH2
CH3
CH4
CH5
IGHN35 IGHN35*01 F 2E CH1 U18694 [3] (1) c
2E CH2
CH3
CH4
CH5
IGHN36 IGHN36*01 F 5NC CH1 U18720 [3] (1) c
5NC CH2
CH3
CH4
CH5
IGHN37 IGHN37*01 F 2P CH1 U18698 [3] (1) c
2P CH2
CH3
CH4
CH5
IGHN38 IGHN38*01 F 2As CH1 U18692 [3] (1) c
2As CH2
CH3
CH4
CH5
IGHN39 IGHN39*01 F 3M CH1 U18707 [3] (1) c
3M CH2
CH3
CH4
CH5
IGHN40 IGHN40*01 F 2T CH1 U18699 [3] (1) c
2T CH2
CH3
CH4
CH5
IGHN41 IGHN41*01 F 3NG CH1 U18710 [3] (1) c
3NG CH2
CH3
CH4
CH5
IGHN42 IGHN42*01 F 1Is CH1 U18689 [3] (1) c
1Is CH2
CH3
CH4
CH5
IGHN43 IGHN43*01 F 3NB CH1 U18709 [3] (1) c
3NB CH2
CH3
CH4
CH5
IGHW1 IGHW1*01 F CH1 U51450 [4] (1) c
CH2 U51450 [4] (1) c
CH3 U51450 [4] (1) c
CH4 U51450 [4] (1) c
CH5 U51450 [4] (1) c
CH6 U51450 [4] (1) c

c: cDNA sequence.
(s): transcript of a secreted chain.

IMGT notes:
  1. (1) C-REGION is partial.
  2. (2) IGHM2 CH2 exon is characterized by a genomic deletion.
IMGT references:
  1. [1] Vazquez M. et al., Mol. Immunol., 29, 1157-1158 (1992). PMID: 1495502
  2. [2] Rumfelt L.L. et al., Proc. Natl. Acad. Sci. USA, 98, 1775-1780 (2001). PMID: 11172027
  3. [3] Greenberg A.S. et al., Nature, 374, 168-173 (1995). PMID: 7877689
  4. [4] Greenberg A.S. et al., Eur. J. Immunol., 26, 1123-1129 (1996). PMID: 8647177
See also (IMGT Scientific chart):