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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT subgroup IMGT gene name IMGT allele name Fct Chromosomal localization R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Isolate Clone names Accession numbers Positions in the sequence (L-V-GENE-UNIT) Secondary accession numbers Isolate Clone names Accession numbers Positions in the sequence (L-V-GENE-UNIT)
IGHV1 IGHV1-1 IGHV1-1*01 P (1) 4 Glennie NW_001594535 [1] 6739..7211
IGHV1-2 IGHV1-2*01 P (1) 4 Glennie NW_001594535 [1] 12029-12524
IGHV1-3 IGHV1-3*01 P (2) 4 Glennie NW_001594535 [1]
IGHV1-4 IGHV1-4*01 P (1) 4 Glennie NW_001594535 [1] 18154-18646
IGHV1-5 IGHV1-5*01 F 4 Glennie NW_001594535 [1] 22787-23295
IGHV1-6 IGHV1-6*01 F 4 Glennie NW_001594535 [1] 26974-27463
IGHV1-7 IGHV1-7*01 F 4 Glennie NW_001594535 [1] 33379-33862
IGHV1-8 IGHV1-8*01 P (3) 4 Glennie NW_001594535 [1] 35720-36198
IGHV1-9 IGHV1-9*01 F 4 Glennie NW_001594535 [1] 41609-42092
IGHV1-10 IGHV1-10*01 P (4) 4 Glennie NW_001594535 [1] 43968-44466 Glennie NW_001634771 [1] complement(17031-17529)
IGHV1-11 IGHV1-11*01 F (5) 4 Glennie NW_001594535 [1]
IGHV1-12 IGHV1-12*01 F 4 Glennie NW_001594535 [1] 58850-59334
IGHV1-13 IGHV1-13*01 F 4 Glennie NW_001594535 [1] 66813-67289
IGHV1-14 IGHV1-14*01 P (1) 4 Glennie NW_001594535 [1] 70795-71321
IGHV1-15 IGHV1-15*01 P (1) 4 Glennie NW_001594535 [1] 93772-94263
IGHV1-16 IGHV1-16*01 F 4 Glennie NW_001594535 [1] complement(126077-126559)
IGHV1-17 IGHV1-17*01 F 4 Glennie NW_001594535 [1] complement(129888-130383)
IGHV1-18 IGHV1-18*01 F 4 Glennie NW_001594535 [1] complement(136698-137213)
IGHV1-19 IGHV1-19*01 P (1) 4 Glennie NW_001594535 [1] complement(152170-152656)
IGHV1-20 IGHV1-20*01 F 4 Glennie NW_001594535 [1] complement(156991-157501)
IGHV1-21 IGHV1-21*01 P (6) 4 Glennie NW_001594535 [1]
IGHV1-22 IGHV1-22*01 F 4 Glennie NW_001594535 [1] complement(167167-167644)
IGHV1-23 IGHV1-23*01 F 4 Glennie NW_001594535 [1] complement(172270-172745)
IGHV1-24 IGHV1-24*01 F 4 Glennie NW_001594535 [1] complement(179396-179871)
IGHV1-25 IGHV1-25*01 F 4 Glennie NW_001594535 [1] complement(187421-187899)
IGHV1-26 IGHV1-26*01 F 4 Glennie NW_001594535 [1] complement(206660-207135)
IGHV1-27 IGHV1-27*01 P (7) 4 Glennie NW_001594535 [1] complement(214544-215022)
IGHV1-28 IGHV1-28*01 F 4 Glennie NW_001594535 [1] complement(218507-218985)
IGHV1-29 IGHV1-29*01 F 4 Glennie NW_001594535 [1] complement(226304-226780)
IGHV1-30 IGHV1-30*01 F 4 Glennie NW_001594535 [1] complement(231104-231583)
IGHV1-31 IGHV1-31*01 F 4 Glennie NW_001594535 [1] complement(238001-238476)
IGHV1-32 IGHV1-32*01 F 4 Glennie NW_001594535 [1] complement(242891-243381)
IGHV1-33 IGHV1-33*01 P (8) 4 Glennie NW_001594535 [1] complement(251190-251675)
IGHV1S1 IGHV1S1*01 P (18) 4 Glennie NW_001634771 [1] complement(1251-2130)
IGHV1S2 IGHV1S2*01 P (19) 4 Glennie NW_001634771 [1] complement(5830-6346)
IGHV1S3 IGHV1S3*01 F 4 Glennie NW_001634771 [1] complement(11797-12285)
IGHV1S4 IGHV1S4*01 F 4 Glennie NW_001634771 [1] complement(19408-19891)
IGHV1S5 IGHV1S5*01 P (7) 4 Glennie NW_001627887 [1] 768-1246
IGHV1S6 IGHV1S6*01 P (10) 4 Glennie NW_001627887 [1] 4088-4810
IGHV1S7 IGHV1S7*01 F 4 Glennie NW_001627887 [1] 6391-6869
IGHV1S9 IGHV1S9*01 F 4 Glennie NW_001627887 [1] 10389-10867
IGHV1S10 IGHV1S10*01 F 4 Glennie NW_001627887 [1] 15125-15603
IGHV1S11 IGHV1S11*01 P (11) 4 Glennie NW_001776005 [1] 8289-8767
IGHV1S12 IGHV1S12*01 P (20) 4 Glennie NW_001776005 [1] 11968-12499
IGHV1S13 IGHV1S13*01 F 4 Glennie NW_001776005 [1] 16434-16924
IGHV1S14 IGHV1S14*01 F 4 Glennie NW_001704450 [1] complement(2751-3249)
IGHV1S15 IGHV1S15*01 P (1) 4 Glennie NW_001704450 [1] complement(5397-5902)
IGHV1S16 IGHV1S16*01 P (21) 4 Glennie NW_001711146 [1]
IGHV2 IGHV2-1 IGHV2-1*01 P (9) 4 Glennie NW_001594535 [1] complement(154267-154790)
IGHV2-2 IGHV2-2*01 P (10) 4 Glennie NW_001594535 [1] complement(169238-169753)
IGHV2-3 IGHV2-3*01 F 4 Glennie NW_001594535 [1] complement(181459-181973)
IGHV2-4 IGHV2-4*01 P (11) 4 Glennie NW_001594535 [1] complement(189534-190050)
IGHV2-5 IGHV2-5*01 P (10) 4 Glennie NW_001594535 [1] complement(196622-197137)
IGHV2-6 IGHV2-6*01 F 4 Glennie NW_001594535 [1] complement(201407-201920)
IGHV2-7 IGHV2-7*01 F 4 Glennie NW_001594535 [1] complement(208573-209087)
IGHV2-8 IGHV2-8*01 P (7) 4 Glennie NW_001594535 [1] complement(216615-217113)
IGHV2-9 IGHV2-9*01 P (22) 4 Glennie NW_001594535 [1] complement(221747-222262)
IGHV2-10 IGHV2-10*01 P (12) 4 Glennie NW_001594535 [1] complement(228370-228884)
IGHV2-11 IGHV2-11*01 P (13) 4 Glennie NW_001594535 [1]
IGHV2S8 IGHV2S8*01 P (1) 4 Glennie NW_001627887 [1] 8263-8782
IGHV3 IGHV3-1 IGHV3-1*01 F 4 Glennie NW_001594535 [1] 4127-4613
IGHV3-2 IGHV3-2*01 P (23) 4 Glennie NW_001594535 [1] 75446-75961
IGHV3-3 IGHV3-3*01 ORF (14) 4 Glennie NW_001594535 [1] complement(140372-140844)
IGHV3-4 IGHV3-4*01 F 4 Glennie NW_001594535 [1] complement(141783-142268)
IGHV3-5 IGHV3-5*01 F 4 Glennie NW_001594535 [1] complement(247091-247561)
IGHV4 IGHV4-1 IGHV4-1*01 P (15) 4 Glennie NW_001594535 [1]
IGHV4-2 IGHV4-2*01 P (15) 4 Glennie NW_001594535 [1] complement(161141-161487)
IGHV5 IGHV5-1 IGHV5-1*01 ORF (16) 4 Glennie NW_001594535 [1] 54941-55421
IGHV5-2 IGHV5-2*01 P (17) 4 Glennie NW_001594535 [1] 91024-91760
IMGT notes:
  1. (1) Frameshift in V-REGION
  2. (2) Frameshift in V-REGION, In frame STOP-CODON in L-PART1 and No V-RS
  3. (3) In frame STOP-CODON in L-PART1, 1st-CYS is replaced by Tyr
  4. (4) INIT-CODON is replaces by Ile
  5. (5) Functionality defined for the available sequence of the gene (truncated gene in 3' because of gaps in the sequence)
  6. (6) truncated V-GENE in 3', INIT-CODON is replaced by Leu, Non canonical DONOR-SPLICE: ngc instread of ngt, Non canonical ACCEPTOR-SPLICE: ntgnn instead of nagnn and frameshift in V-REGION
  7. (7) In frame STOP-CODON in V-REGION
  8. (8) Frameshift in V-REGION, 1st-CYS is replaced by Pro
  9. (9) Frameshift in V-REGION, INIT-CODON is replaced by Leu
  10. (10) Frameshift in V-REGION, INIT-CODON is replaced by Arg
  11. (11) Frameshift in V-REGION, non canonical DONOR-SPLICE: nat instead of ngt
  12. (12) INIT-CODON is replaced by Arg, non canonical DONOR-SPLICE: nat instead of ngt
  13. (13) Frameshift in V-REGION, No L-PART1, L-PART2 and V-RS
  14. (14) Non canonical ACCEPTOR-SPLICE: natnn instead of nagnn
  15. (15) Frameshift in V-REGION, No L-PART1 and L-PART2
  16. (16) 2nd-CYS is replaced by Val
  17. (17) In frame STOP-CODON in FR2-IMGT, INIT-CODON is replaced by Ile, 2nd-CYS is replaced by Trp
  18. (18) Frameshift in V-REGION, Insertion of undefined nucleotides between L-PART2 et FR1-IMGT
  19. (19) Frameshift in V-REGION, INIT-CODON is replaced by Thr
  20. (20) Frameshift in L-PART1
  21. (21) Frameshift in V-REGION, No L-PART1
  22. (22) Frameshift in V-REGION, 2nd-CYS is replaced by Trp
  23. (23) Frameshift in V-REGION, INIT-CODON is replaced by Ile, non canonical DONOR-SPLICE ntg instead of ngt
IMGT references:
  1. [1] Warren,W.C. et al., Nature 453 (7192), 175-183 (2008). PMID: 18464734
See also (IMGT Scientific chart):