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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHM1 IGHM1*01 F cos5 CH1 AF003844 [1]
CH2 AF003845 [1]
CH3 AF003846 [1]
CH4(including CHS) AF003847 [1]
IGHM2 IGHM2*01 F 20182 CH1 AF003862 [1]
CH2 AF003863 [1]
CH3 AF003864 [1]
CH4(including CHS) AF003865 [1]
IGHM3 IGHM3*01 F 20442 CH1 AF003839 [1] c(s)
CH2 AF003839 [1] c(s)
CH3 AF003839 [1] c(s)
CH4(including CHS) AF003839 [1] c(s)
IGHM4 IGHM4*01 F 3171 CH1 AF004359 [1] c(s)
CH2 AF004359 [1] c(s)
CH3 AF004359 [1] c(s)
CH4(including CHS) AF004359 [1] c(s)
IGHM5 IGHM5*01 F 3173 CH1 AF004360 [1] c(m)
CH2 AF004360 [1] c(m)
CH3 AF004360 [1] c(m)
CH4 AF004360 [1] c(m)
M1 AF004360 [1] (2) c(m)
M2 (2)
IGHM6 IGHM6*01 F 3631 CH4(including CHS) AF003852 [1] (1)
IGHM7 IGHM7*01 P (3) 20457 CH4(including CHS) AF003851 [1]
IGHM8 IGHM8*01 F 3430 CH1 AF003853 [1] c(m)

c: cDNA sequence.
(s): transcript of a secreted chain.
(m): transcript of a membrane chain.

IMGT notes:
  1. (1) C-REGION is partial: CHS is partial in 3'.
  2. (2) C-REGION is partial: M1 is partial in 3'.
  3. (3) STOP-CODON in the C-REGION (4 nucleotides DELETION), leading to a frameshift.
IMGT references:
  1. [1] Rast J.P. et al., Immunogenetics, 47, 234-245 (1998). PMID: 9435342
See also (IMGT Scientific chart):