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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHD1 (1) IGHD1*01 F AF003840 [1]
IGHD2 (1) IGHD2*01 F AF003840 [1]
IGHD3 IGHD3*01 (F) + + AF003946 [1] ~VDJ
IGHD4 IGHD4*01 (F) + + AF003839 [1] #c
IGHD5 IGHD5*01 (F) + + AF004359 [1] #c
IGHD6 IGHD6*01 (F) + + AF004360 [1] #c
IGHD7 IGHD7*01 (F) + + AF003853 [1] #c
IGHD8 (2) IGHD8*01 F AF003841 [1]
IGHD9 (2) IGHD9*01 F AF003841 [1]
IGHD10 IGHD10*01 (F) + + AF003854 [1] #c
IGHD11 IGHD11*01 (F) + + AF003855 [1] #c
IGHD12 IGHD12*01 (F) + + AF003856 [1] #c
IGHD13 IGHD13*01 (F) + + AF003857 [1] #c
IGHD14 IGHD14*01 (F) + + AF003858 [1] #c
IGHD15 IGHD15*01 (F) + + AF003859 [1] #c
IGHD16 IGHD16*01 (F) + + AF003860 [1] #c
IGHD17 IGHD17*01 (F) + + AF003861 [1] #c

#c: rearranged cDNA.
~VDJ: VDJ genomic DNA rearranged in the cassette.

IMGT notes:
  1. (1) IGHD1 and IGHD2 are localized on the same cassette: Cassette 1.
  2. (2) IGHD8 and IGHD9 are localized on the same cassette: Cassette 9.
IMGT references:
  1. [1] Rast J.P. et al., Immunogenetics, 47, 234-245 (1998). PMID: 9435342
See also (IMGT Scientific chart):