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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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In the "Clone names" column of "IMGT/LIGM-DB reference sequences" are shown the names of the lambda phages (for genomic sequences) or of the clones (for cDNA), and between parentheses cell lines, from which are derived the reference sequences.

IMGT gene name IMGT allele name Fct Chromosomal localization T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Clone names Accession numbers Positions in the sequence
TRGC1 TRGC1*01 (1) F 7p14 lambda-D19 (D-PLL) EX1 M14996 [3] X02758 [1] (2)
T-gamma-5 M17325 [4] (3) c
AF159056 [6]
BC072387 [7] c
BC105589 [7] c(st)
M16768 [8] c
EX2 M14997 [3] T-gamma-5 M17325 [4] (3) c
AF159056 [6]
BC072387 [7] c
BC105589 [7] c(st)
M16768 [8] c
EX3 M14998 [3] T-gamma-5 M17325 [4] (3) c
AF159056 [6]
BC072387 [7] c
BC105589 [7] c(st)
M16768 [8] c
TRGC1*02 (1) F 7p14 lambda-R-gamma (Raji) EX1 M14999 [3] (2) X02757 [1] (2)
EX2
EX3
TRGC1*03 (1) (F) 7p14 TCRGV9, V2 EX1 BC072396 [7] c BC030554 [7] c
HGP02 M27334 [11] c
X72500 [13] (6) c
EX2 BC072396 [7] c BC030554 [7] c
HGP02 M27334 [11] c
X72500 [13] (6) c
EX3 BC072396 [7] c BC030554 [7] c
HGP02 M27334 [11] c
X72500 [13] (6) c
TRGC1*04 (1) (F) 7p14 EX1 AF151103 [9] c
EX2 AF151103 [9] c
EX3 AF151103 [9] c
TRGC1*05 (1) (F) 7p14 TCRGV9, V2 EX1 BC062761 [7] c
EX2 BC062761 [7] c
EX3 BC062761 [7] c
TRGC2 (4) TRGC2*01(2x) (5) F 7p14 lambda-D7 (D-PLL) EX1 M15002 [3] pTgamma-1(HPB-MLT) M13231 [2] c
pTgamma-1 (HPB-MLT) EX2T M13231 [2] c
EX2 M13231 [2] c
EX3 M13231 [2] c
TRGC2*02(2x) (5) F 7p14 lambdaD11 (D-PLL) EX1 M15001 [3] BC017861 [7] c
lambdaS9 (SUPT1) EX2R M15004 [3] BC017861 [7] c
EX2 M15005 [3] BC017861 [7] c
EX3 M15007 [3] BC017861 [7] c
TRGC2*03(2x) (F) 7p14 F-gamma-7 (Fro 2.2) EX1 M17324 [4] c
EX2R M17324 [4] c
EX2 M17324 [4] c
EX3 M17324 [4] c
TRGC2*04(2x) F 7p14 EX1 AF159056 [6]
EX2R AF159056 [6]
EX2 AF159056 [6]
EX3 AF159056 [6]
TRGC2*05(3x) (F) 7p14 p-gamma-1 (PEER) EX1 M17323 [4] c M30894 [12] c
lambdaR12 (RPMI 8402) EX2T M25318 [5] p-gamma-1(PEER) M17323 [4] c
M30894 [12] c
p-gamma-1 (PEER) EX2R M17323 [4] c M30894 [12] c
EX2 M17323 [4] c M30894 [12] c
EX3 M17323 [4] c M30894 [12] c
TRGC2*06(2x) (F) 7p14 K (MOLT13 leukemia) EX1 Y00790 [10] c
EX2R Y00790 [10] c
EX2 Y00790 [10] c
EX3 Y00790 [10] c
TRGC2*07(2x) (F) 7p14 HGP08 EX1 M27331 [11] c
EX2R M27331 [11] c
EX2 M27331 [11] c
EX3 M27331 [11] c
TRGC2*08(2x) (F) 7p14 HGP06 EX1 M27332 [11] c
EX2R M27332 [11] c
EX2 M27332 [11] c
EX3 M27332 [11] c

c: cDNA sequence.
(st): sterile transcipt.

IMGT notes:
  1. (1) TRGC1*01 and TRGC1*02 alleles were previously designated as gamma1b (D19 gamma1) and gamma1a (Raji gamma1), respectively [15].
  2. (2) Partial C-GENE: partial EX1 in 3'.
  3. (3) Partial C-REGION: partial EX1 in 5'.
  4. (4) The TRGC2 gene contains four or five exons due to the duplication (EX2T-EX2 or EX2R-EX2) or triplication (EX2T-EX2R-EX2) of exon 2 [5]. (2x) or (3x) indicates the duplication or triplication of the TRGC2 exon 2; respectively [14].
  5. (5) TRGC2*01(2x) and TRGC2*02(2x) alleles were previously designated as gamma2b (D7 gamma2) and gamma2a (D11 gamma2), respectively [15].
  6. (6) Productive, truncated chain at its C-terminal end following introduction of a STOP-CODON at position 7 of EX3 to obtain a soluble form.
IMGT references:
  1. [1] Lefranc M.-P. and Rabbitts T.H., Nature, 316, 464-466 (1985). PMID: 2991773
  2. [2] Dialynas D.P. et al., Proc. Natl. Acad. Sci. U.S.A., 83, 2619-2623 (1986). PMID: 3458221
  3. [3] Lefranc M.-P. et al., Proc. Natl. Acad. Sci. U.S.A., 83, 9596-9600 (1986). PMID: 2879283
  4. [4] Pelicci P.G. et al., Science, 237, 1051-1055 (1987). PMID: 3112943
  5. [5] Buresi C. et al., Immunogenetics, 29, 161-172 (1989). PMID: 2564370
  6. [6] Zhan M. et al., Unpublished.
  7. [7] Strausberg R.L. et al., Proc. Natl. Acad. Sci. U.S.A., 99, 16899-16903 (2002). PMID: 12477932
  8. [8] Krangel M.S. et al., Science, 237, 64-67 (1987). PMID: 2955517
  9. [9] Essand M. et al., Proc. Natl. Acad. Sci. U.S.A., 96, 9287-9292 (1999). PMID: 10430935
  10. [10] Hochstenbach F. et al., J. Exp. Med., 168, 761-776 (1988). PMID: 3261778
  11. [11] Yoshikai Y. et al., Eur. J. Immunol., 17, 119-126 (1987). PMID: 2949984
  12. [12] Littman D.R. et al., Nature, 326, 85-88 (1987). PMID: 3102973
  13. [13] Davodeau F. et al., J. Biol. Chem., 268, 15455-15460 (1993). PMID: 8340374
  14. [14] Ghanem N. et al., Hum genet., 86, 450-456 (1991). PMID: 1673112
  15. [15] Lefranc M.-P. et al., Proc. Natl. Acad. Sci. U.S.A., 83, 9596-9600 (1986). PMID: 2879283
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