Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) > 1. Locus and genes

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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Positions in contigs: limits from the first nucleotide of V-REGION to the last nucleotide.

IMGT subgroup IMGT gene name IMGT allele name Fct Haplotypes R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence (V-REGION) Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence (V-REGION)
IGHV1 IGHV1S1 IGHV1S1*01 F F-I (24) 38A2 AY386694 [1] 2148-2434
IGHV1S2 IGHV1S2*01 P F-I (24) 38A2 AY386694 [1] (1) 9514-9799
IGHV1S3 IGHV1S3*01 P F-I (24) 38A2 AY386694 [1] (2) 19395-19691
IGHV1S4 IGHV1S4*01 P F-I (24) 38A2 AY386694 [1] (3) 35175-35448
IGHV1S5 IGHV1S5*01 P F-I (24) 38A2 AY386694 [1] (4) 47680-47974
IGHV1S6 IGHV1S6*01 P F-I (24) 38A2 AY386694 [1] (4) 52532-52820
IGHV1S7 IGHV1S7*01 F F-I (24) 38A2 AY386694 [1] 61809-62101
IGHV1S8 IGHV1S8*01 F F-I (24) 38A2 AY386694 [1] 74275-74567
IGHV1S9 IGHV1S9*01 P F-I (24) 38A2 AY386694 [1] (5) 79156-79450
IGHV1S10 IGHV1S10*01 P F-I (24) 38A2 AY386694 [1] (6) 84811-85104
IGHV1S11 IGHV1S11*01 P F-I (24) 38A2 AY386694 [1] (5) 95728-96010
IGHV1S12 IGHV1S12*01 P F-I (24) 38A2 AY386694 [1] (7) 102237-102505
IGHV1S13 IGHV1S13*01 F F-I (24) 38A2 AY386694 [1] 105318-1056
IGHV1S14 IGHV1S14*01 P F-I (24) 38A2 AY386694 [1] (8) 107577-107770
IGHV1S15 IGHV1S15*01 P F-I (24) 38A2 AY386694 [1] (5) 118044-118335
IGHV1S16 IGHV1S16*01 P F-I (24) 38A2 AY386694 [1] (4) 125557-125850
IGHV1S17 IGHV1S17*01 F F-I (24) 225P18 AY386697 [1] 4344-4630
IGHV1S18 IGHV1S18*01 P F-I (24) 225P18 AY386697 [1] (9) 9266-9560
IGHV1S19 IGHV1S19*01 P F-I (24) 225P18 AY386697 [1] (10) 15914-16134
IGHV1S20 IGHV1S20*01 P F-I (24) 225P18 AY386697 [1] (11) 22513-22793
IGHV1S21 IGHV1S21*01 P F-I (24) 225P18 AY386697 [1] (12) 32833-33119
IGHV1S22 IGHV1S22*01 P F-I (24) 225P18 AY386697 [1] (13) 37749-38043
IGHV1S23 IGHV1S23*01 P F-I (24) 225P18 AY386697 [1] (10) 44644-44864
IGHV1S24 IGHV1S24*01 F F-I (24) 225P18 AY386697 [1] 49458-49744
IGHV1S25 IGHV1S25*01 F F-I (24) 225P18 AY386697 [1] (14) 56920-57206 VH17-1-9 U18652 [2] 241-527
IGHV1S26 IGHV1S26*01 F F-I (24) 225P18 AY386697 [1] (15) 63689-63978 VH12-1-6 U18651 [2] 241-530
IGHV1S27 IGHV1S27*01 P F-I (24) 225P18 AY386697 [1] (16) 71217-71508
IGHV1S28 IGHV1S28*01 F F-I (24) 225P18 AY386697 [1] 76272-76561
IGHV1S29 IGHV1S29*01 P F-I (24) 225P18 AY386697 [1] (17) 79023-79309
IGHV1S30 IGHV1S30*01 P F-I (24) 225P18 AY386697 [1] (18) 83478-83769 AF177017 [3] 241-532
IGHV1S31 IGHV1S31*01 F F-I (24) 225P18 AY386697 [1] 88024-88313 M93182 [4] 239-526
IGHV1S32 IGHV1S32*01 P F-I (24) 225P18 AY386697 [1] (19) 91243-91532
IGHV1S33 IGHV1S33*01 P F-I (24) 225P18 AY386697 [1] (20) 95940-96232 219D23 AY386695 [1] 2829-3121
IGHV1S34 IGHV1S34*01 F F-I (24) 225P18 AY386697 [1] 100974-1012 219D23 AY386695 [1] 7863-8152
M93172 [4] 241-528
IGHV1S35 IGHV1S35*01 P (25) M12180 [5] (21) 401-667
IGHV1S36 IGHV1S36*01 F (25) M12180 [5] (22) 3485-3771
IGHV1S37 IGHV1S37*01 P RVH701 M60121 [6] (23) 221-507
IGHV1S39 IGHV1S39*01 F M60336 [7] 87-373
IGHV1S40 IGHV1S40*01 F VH1-a3 M93173 [4] 673-968
IGHV1S42 IGHV1S42*01 F M93177 [4] 248-535
IGHV1S43 IGHV1S43*01 F M93179 [4] 241-537
IGHV1S44 IGHV1S44*01 F M93181 [4] 241-525
IGHV1S45 IGHV1S45*01 F M93183 [4] 241-539
IGHV1S46 IGHV1S46*01 P M93184 [4] 241-534
IGHV1S47 IGHV1S47*01 F M93185 [4] 241-534
IGHV1S48 IGHV1S48*01 P M93186 [4] (19) 229-522
IGHV1S49 IGHV1S49*01 F ali F-I [8] Alicia 1E6 AF176997 [3] 378-665
IGHV1S50 IGHV1S50*01 F ali F-I [8] Alicia SK5084 AF176998 [3] 378-665
IGHV1S51 IGHV1S51*01 F ali F-I [8] Alicia sk5064 AF176999 [3] 378-665
IGHV1S52 IGHV1S52*01 F ali F-I [8] Alicia sk5074 AF177000 [3] 378-665
IGHV1S53 IGHV1S53*01 F ali F-I [8] Alicia SK5332 AF177001 [3] 378-668
IGHV1S54 IGHV1S54*01 F ali F-I [8] Alicia SK5312 AF177002 [3] 355-645
IGHV1S55 IGHV1S55*01 F ali F-I [8] Alicia SK5252 AF177003 [3] 355-645
IGHV1S56 IGHV1S56*01 F ali F-I [8] Alicia 9C4 AF177004 [3] 378-668
IGHV1S57 IGHV1S57*01 F ali F-I [8] Alicia sk5066 AF177005 [3] 378-665
IGHV1S58 IGHV1S58*01 F ali F-I [8] Alicia sk5086 AF177006 [3] 377-667
IGHV1S59 IGHV1S59*01 F ali F-I [8] Alicia 1B3 AF177007 [3] 377-664
IGHV1S60 IGHV1S60*01 F ali F-I [8] Alicia 4A4 AF177008 [3] 377-664
IGHV1S61 IGHV1S61*01 F ali F-I [8] Alicia 6A1 AF177009 [3] 377-664
IGHV1S62 IGHV1S62*01 F ali F-I [8] Alicia 8E1 AF177010 [3] 377-664
IGHV1S63 IGHV1S63*01 F ali F-I [8] Alicia 10A2 AF177011 [3] 377-664
IGHV1S64 IGHV1S64*01 F ali F-I [8] Alicia 1C3 AF177012 [3] 377-664
IGHV1S65 IGHV1S65*01 F ali F-I [8] Alicia 4C4 AF177013 [3] 377-664
IGHV1S66 IGHV1S66*01 F ali F-I [8] Alicia 1A6 AF177014 [3] 377-664
IGHV1S67 IGHV1S67*01 F ali F-I [8] Alicia SK5314 AF177015 [3] 354-641
IGHV1S68 IGHV1S68*01 F ali F-I [8] Alicia SK5310 AF177016 [3] 357-644
IGHV1S69 IGHV1S69*01 F VH1-a1 M93171 [4] 239-522
IMGT notes:
  1. (1) Pseudogene because frameshift in FR1-IMGT and STOP-CODON in FR3-IMGT
  2. (2) Pseudogene because frameshift and STOP-CODON in FR1-IMGT
  3. (3) Pseudogene because not found FR3-IMGT and CDR3-IMGT
  4. (4) Pseudogene because frameshift in FR1-IMGT
  5. (5) Pseudogene because frameshift in FR2-IMGT
  6. (6) Pseudogene because frameshift in FR1-IMGT and CDR1-IMGT
  7. (7) Pseudogene because FR3-IMGT contains only 30 AA and frameshift
  8. (8) Pseudogene because not found label before FR2-IMGT
  9. (9) Pseudogene because frameshift in FR3-IMGT
  10. (10) Pseudogene because not found L-PART1 and FR1-IMGT
  11. (11) Pseudogene because frameshift in FR2-IMGT and FR3-IMGT
  12. (12) Pseudogene because not found L-PART1
  13. (13) Pseudogene due to frameshift in FR3-IMGT (1nt deleted)
  14. (14) Mutation in V-HEPTAMER and only 22 pb V-SPACER
  15. (15) Only 22 pb in V-SPACER
  16. (16) Pseudogene because frameshift in FR1-IMGT and not found L-PART1 and V-NONAMER
  17. (17) Pseudogene because STOP-CODON in L-PART1
  18. (18) Pseudogene because frameshift in FR1-IMGT and not found V-NONAMER
  19. (19) Pseudogene because STOP-CODON in FR1-IMGT
  20. (20) Pseudogene because not found L-PART1 and V-NONAMER
  21. (21) Pseudogene because STOP-CODON in FR3-IMGT and non canonical ACCEPTOR-SPLICE: ntgnn instead of nagnn
  22. (22) Non canonical ACCEPTOR-SPLICE: ntgnn instead of nagnn
  23. (23) Pseudogene because deletion of 1 nt in L-PART1
  24. (24) BAC clone from a rabbit of normal haplotype F-I. (07/10/2010, e-mail from R. Mage to M.-P. Lefranc)
  25. (25) Clone from a rabbit of VHa3 allotype. (07/10/2010, e-mail from R. Mage to M.-P. Lefranc)
IMGT references:
  1. [1] Ros F. et al., Gene, 330, 49-59 (2004). PMID: 15087123
  2. [2] Chen H.T. et al., J. Immunol., 154, 6365-6371 (1995) . PMID: 7759874
  3. [3] Zhu X. et al., J. Immunol., 163, 3313-3320 (1999). PMID: 10477601
  4. [4] Knight K.L. et al., Cell, 60, 963-970 (1990). PMID: 2317867
  5. [5] Bernstein K.E. et al., J. Immunol., 134, 3480-3488 (1985) . PMID: 2984292
  6. [6] Roux K.H. et al., J. Immunol., 146, 2027-2036 (1991). PMID: 1900880
  7. [7] Fitts M.G et al., J. Immunol., 145, 2713-2717 (1990) . PMID: 2120337
  8. [8] Allegrucci M. et al., Proc. Natl. Acad. Sci., 87, 5444-5448 (1990) . PMID: 2115171
See also (IMGT Scientific chart):