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In cattle (bovine, Bos taurus) and sheep (ovine, Ovis aries), the TRG genes are organized in two separate loci on chromosome 4:

Bovine (Bos taurus) TRG locus on chromosome 4 (4q3.1 and 4q1.5-2.2)

Locus representation bovine TRG

Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken into account in the length of the lines and included in the numbers displayed at the right end of the lines.
A dotted line ... indicates the distance in kb (kilobase) between the locus and its bornes (5' borne and the most 5' gene in the locus and/or 3' borne and the most 3' gene in the locus) on the top and bottom lines, respectively. These distances are not represented at scale and are not included in the numbers displayed at the right ends of these two lines.

Arrows indicate the TRGC cassettes and the transcriptional orientation of their genes.

* In AY644518 TRGV5-2 is rearranged with TRGJ2-1 and TRGV6-2 is rearranged with TRGJ6-1.

Locus representation with only the functional genes: Bovine (Bos taurus) TRG

Locus representation bovine TRG

* When needed, indicate the presence of allele(s) with another functionality: see above Bovine (Bos taurus) TRG locus

IMGT references:
  1. [1] Ishiguro, N. et al., Immunogenetics, 38, 437-443 (1993). PMID: 8406615
  2. [2] Hein, W. R. et al., Immunology, 91, 58-64 (1997). PMID: 9203966
  3. [3] Lahmers, K.K. et al., J. Leukoc. Biol., 77, 199-208 (2005). PMID: 15522917
  4. [4] Herzig, C. et al., Immunogenetics, 58, 138-151 (2006). PMID: 16541255
  5. [5] Conrad, M. et al., Vet. Immunol. Immunopathol.,115, 346-356 (2007). PMID: 17141331
Last updated:
Joumana Jabado Michaloud and Marie-Paule Lefranc
Chantal Ginestoux