The orientation of the human IGH locus on the chromosome is reverse (REV).
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
SWITCH sequences are represented
by a filled circle upstream of the IGHC genes.
IGHV genes which correspond to insertion/deletion polymorphisms but are not yet precisely located are not shown.
The Human (Homo sapiens) IGHV genes belong to 7 subgroups (Gene tables: Human IGHV) which are part of three clans (Figure IGHV clans). One additional clan only contains one pseudogene. Clans comprise, respectively:
* When needed, indicate the presence of allele(s) with another functionality: see above Human (Homo sapiens) IGH locus