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House mouse (Mus musculus) TRB locus on chromosome 6 (6B1)

The orientation of the house mouse (Mus musculus) TRB locus on the chromosome 6 (6B1) is forward (FWD).

Locus representation mouse TRB

Legend:
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken into account in the length of the lines and included in the numbers displayed at the right end of the lines.
A dotted line ... indicates the distance in kb (kilobase) between the locus and its bornes (5' borne and the most 5' gene in the locus and/or 3' borne and the most 3' gene in the locus) on the top and bottom lines, respectively. These distances are not represented at scale and are not included in the numbers displayed at the right ends of these two lines.

A single arrow shows the most 3' TRBV gene whose polarity is opposite to that of the D-J-C-CLUSTER.

TRBV genes are designated by a number for the subgroup followed, whenever there are several genes belonging to the same subgroup, by a dash and a number for their relative localization. Numbers increase from 5' to 3' in the locus.

Bornes of the house mouse (Mus musculus) TRB locus

• MOXD2 (5' borne) has been identified 3,8 kb upstream of TRBV1 (F), the most 5' gene in the Mus musculus TRB locus. PRSS58 (serine protease 58) (5' borne) has been identified 3,4 kb dowstream of TRBV1 (F), the most 5' gene in the locus.
• EPHB6 (EPH receptor B6) (3' borne) has been identified 47 kb downstream of TRBV31 (F), the most 3' gene in the locus.

Locus representation with only the functional genes: House mouse (Mus musculus) TRB

Locus representation mouse TRB

* When needed, indicate the presence of allele(s) with another functionality: see above House mouse (Mus musculus) TRB locus

IMGT references:
  1. [1] Rowen et al., unpublished AE000663-AE000665 (1997).
  2. [2] Bosc, N., Folch, G., Ginestoux, C., Giudicelli, V. and Lefranc, M.-P. IMGT overview: the mouse T cell receptor beta TRB genes. 19th International Mouse Genome Conference (IMGC), November 5-8, 2005, Strasbourg, France (2005). .
Created:
15/01/2001
Last updated:
15/10/2015
Authors:
Nathalie Bosc, Marie-Paule Lefranc
Editors:
Chantal Ginestoux