IMGT Repertoire (IG and TR)

Alignment of alleles: western lowland gorilla (Gorilla gorilla gorilla) TRGVA

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.

Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                          
                                          
                                           1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                           L   I   R   L   E   Q   L   A   H       V   L   G   H   *   G   S   L   V   I  
  IMGT000103 TRGVA*02 P V-REGION gDNA     ctc atc agg ctg gag cag ctg gcc cat ... gtc ctg ggg cac tag gga agc ttg gtc atc 



                                                                  ___________________CDR1-IMGT____________________        
                                          
                                           21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                           L   Q   C   V   V   R   T   R   I                               S   Y   I   H  
  IMGT000103 TRGVA*02 P V-REGION gDNA     ctg cag tgc gtg gtc cgc acc agg atc ... ... ... ... ... ... ... agc tac atc cac 



                                                                                                          _______________C
                                          
                                           41  42 42A  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                           W   Y   Q   Q   Q   K   G   Q   V   P   E   A   L   H   Q   L   A   M          
  IMGT000103 TRGVA*02 P V-REGION gDNA     tgg tac cag cag cag aag ggc cag gtc cct gag gca ctc cac cag ctg gcc atg ... ... 



                                          DR2-IMGT________________                                                        
                                          
                                           60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                       S   K   L   D   V   Q   W   D   S   I   L   K   A   D   K   I   T  
  IMGT000103 TRGVA*02 P V-REGION gDNA     ... ... ... tcc aag ttg gat gtg cag tgg gat tcc atc ctg aaa gca gat aaa atc aca 



                                                                                                                          
                                          
                                           80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                           A   K       D   G   S   S   C   T   L   A   V   L   K   L   E   T   G   I   E  
  IMGT000103 TRGVA*02 P V-REGION gDNA     gcc aag ... gat ggc agc agc tgt acc ttg gca gta ctg aag ttg gag aca ggc atc gag 



                                                              _____CDR3-IMGT______
                                          
                                          100 101 102 103 104 105 106 107 108 109 
                                           G   M   N   Y   C   T   A   W   A   L  
  IMGT000103 TRGVA*02 P V-REGION gDNA     ggc atg aac tac tgc aca gcc tgg gcc ctg

Legend:

*: STOP-CODON

This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).

Created:: 27/04/2022
Last updated:: 08/11/2022
Authors:: Joanna Maria Rosinska, Chahrazed Debbagh