IMGT Repertoire (IG and TR)

Alignment of alleles: Ring-tailed lemur (Lemur catta) IGHA

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.

Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Letters in bold correspond to additional positions in the IMGT unique numbering.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                    
                                    
                                    1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                     X   S   A   A   S   P   V   V   F   P   L   S   L   P   S   S  
  IMGT000097 IGHA*01 F CH1 gDNA                     ntg tcc gcg gcc agc ccc gtg gtc ttc cca ctg agc ctt cca agc tct 



                                                _____AB_____                                            ____________
                                                15.1    15.3                                                        
                                     13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                     E   S                   G   E   L   V   V   I   G   C   L   V   Q   G   F   F  
  IMGT000097 IGHA*01 F CH1 gDNA     gag agc ... ... ... ... ggc gag ctc gtg gtc atc ggc tgc ctg gtc cag ggc ttc ttc 



                                    _______BC___________________                            _____________CD_________
                                                                                            45.1    45.3    45.5    
                                     30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                     P   S       E   P   L   N   V   T   W   N   Q   D   G   D   N   V              
  IMGT000097 IGHA*01 F CH1 gDNA     ccg tcg ... gag ccg ctg aac gtg acc tgg aac caa gac ggg gac aat gtg ... ... ... 



                                    ____                                ___________________________DE_______________
                                    45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                         77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         T   V   I   N   Y   P   L   T   E   A   D   S   E                       G  
  IMGT000097 IGHA*01 F CH1 gDNA     ... acc gtc ata aac tat ccg ctc acc gag gct gac tct gag ... ... ... ... ... ggc 



                                    ____________                                                ___EF___            
                                        85.2                                                    96.1                
                                    85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                     L   Y   T   T   T   S   Q   L   T   L   P   A   D   Q   C           P   A   G  
  IMGT000097 IGHA*01 F CH1 gDNA     ctg tac acc acg acc agc cag ctg aca ctg ccg gcc gac cag tgc ... ... ccg gct ggc 



                                                        _________________________FG_________________________        
                                    
                                    100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                     T   F   L   Q   C   H   V   E   H   N               S   N   F   N   K   D   V  
  IMGT000097 IGHA*01 F CH1 gDNA     acg ttc ctg cag tgc cac gtg gag cac aac ... ... ... tcg aac ttc aac aag gat gtg 



                                                    
                                    
                                    120 121 122 
                                     S   V   A  
  IMGT000097 IGHA*01 F CH1 gDNA     tcc gtg gcc tg

                                  
                                  
                                   1   2   3   4   5   6   7  
                                   H   P   P   P   S   P   S  
  IMGT000097 IGHA*01 F H gDNA     cac cca cct ccg tcc ccc tcc

                                                                                                                    
                                    
                                    1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                             C   C   H   P   Q   L   S   L   H   P   P   A   L   E  
  IMGT000097 IGHA*01 F CH2 gDNA                             tgc tgc cat ccc caa ctg tca ctg cac ccg ccg gcc ctc gag 



                                                _____AB_____                                            ____________
                                                15.1    15.3                                                        
                                     13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                     D   L   L   L           G   S   D   A   N   L   K   C   T   L   R   G   L   V  
  IMGT000097 IGHA*01 F CH2 gDNA     gac ctg ctc ctg ... ... ggc tca gac gcc aac ctc aag tgc aca ctg cgc ggc ctg gtg 



                                    _______BC___________________                            _____________CD_________
                                                                                            45.1    45.3    45.5    
                                     30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                     N   P       E   N   A   T   F   T   W   Q   P   S   E   G   K                  
  IMGT000097 IGHA*01 F CH2 gDNA     aac ccc ... gag aac gcc acc ttc acc tgg cag ccc tcc gag ggg aag ... ... ... ... 



                                    ____                                ___________________________DE_______________
                                    45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                         77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         K   A   E   L   G   E   P   V   R   D   S   C                           G  
  IMGT000097 IGHA*01 F CH2 gDNA     ... aag gcc gag ctg ggg gaa ccc gtg cgg gac tcc tgc ... ... ... ... ... ... ggc 



                                    ____________                                                ___EF___            
                                        85.2                                                    96.1                
                                    85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                     C   Y   S   V   S   S   V   L   P   G   C   A   E   P   W           N   S   G  
  IMGT000097 IGHA*01 F CH2 gDNA     tgc tac agt gtg tcc agc gtc ctg ccc ggc tgc gcg gag cca tgg ... ... aac agc ggg 



                                                        _________________________FG_________________________        
                                    
                                    100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                     Q   T   F   T   C   S   A   T   H   P   E           S   E   T   T   L   T   A  
  IMGT000097 IGHA*01 F CH2 gDNA     cag acc ttc acg tgc agc gcc acc cac cct gag ... ... tcc gag acc aca cta act gcc 



                                                            
                                    
                                    120 121 122 123 124 125 
                                     T   I   A   K   G   S  
  IMGT000097 IGHA*01 F CH2 gDNA     acc atc gcc aaa ggc tca

                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         G   D   N   F   R   P   Q   V   H   L   L   P   P   P   S   E  
  IMGT000097 IGHA*01 F CH3-CHS gDNA                     ggg gac aac ttc cgg ccc cag gtc cac ctg cta ccg ccg ccg tcg gag 



                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         E   L   A   L           N   E   L   V   T   L   T   C   L   V   R   G   F   S  
  IMGT000097 IGHA*01 F CH3-CHS gDNA     gag ctg gcc ctg ... ... aac gag ctg gtg acg ctg acg tgc ctg gtg cgc ggc ttc agc 



                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P           E   Q   V   L   V   R   W   L   H   G   S   Q   E   L   P   R   G  
  IMGT000097 IGHA*01 F CH3-CHS gDNA     ccc ... ... gag cag gtg ctg gtg cgc tgg ctg cac ggg tcc cag gag ctg ccc cgc ggg 



                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                             G   Y   L   T   W   P   P   R   Q   E   P   G   Q   G               A   T  
  IMGT000097 IGHA*01 F CH3-CHS gDNA     ... ggc tac cta acc tgg ccc ccc cgg cag gag ccc ggc cag ggc ... ... ... gcc acc 



                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                         T   F   A   V   T   S   V   L   R   V   T   A   E   S   W           K   N   G  
  IMGT000097 IGHA*01 F CH3-CHS gDNA     acc ttc gcg gtg acc agc gtg ctg cgc gtg acg gcc gag tcc tgg ... ... aag aac ggg 



                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         D   N   F   S   C   I   V   G   H   E   A       L   P   Q   A   F   T   Q   K  
  IMGT000097 IGHA*01 F CH3-CHS gDNA     gac aac ttc tcc tgc atc gtg ggc cac gag gcc ... ctg ccc cag gcc ttc acg cag aag 



                                                                            ______________________________________CHS___
                                        
                                        120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                         T   I   D   R   L   A               G   K   P   T   H   V   N   V   S   V   V  
  IMGT000097 IGHA*01 F CH3-CHS gDNA     acc atc gac cgc ctg gcg ... ... ... ggt aaa ccc acc cac gtc aac gtg tcc gtg gtc 



                                        ____________________________________
                                        
                                        140 141 142 143 144 145 146 147 148 
                                         M   A   E   V   D   G   V   C   Y  
  IMGT000097 IGHA*01 F CH3-CHS gDNA     atg gca gag gtg gac ggc gtg tgc tac

                                  
                                  
                                   1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                   V   C   C   R   L   A   G   A   A   S   L   R   G   A   G   P   A   A   G   D  
  IMGT000097 IGHA*01 F M gDNA     gtg tgt tgc agg ttg gcg gga gcc gct tcc ctg cgt gga gct gga cct gcc gca gga gac 



                                  
                                  
                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                   P   G   G   G   S   P   G   G   Q   P   V   A   H   H   H   H   L   P   H   A  
  IMGT000097 IGHA*01 F M gDNA     cct gga gga ggg agt ccc ggg ggc cag cct gtg gcc cac cac cat cac ctt cct cac gct 



                                  
                                  
                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                   L   P   A   E   P   V   L   Q   H   S   A   D   R   D   K   R   P   G   P   P  
  IMGT000097 IGHA*01 F M gDNA     ctt cct gct gag cct gtt cta cag cac agc gct gac cgt gac aag cgt ccg ggg ccc ccc 



                                  
                                  
                                   61  62  63  64  65  66  67  68 
                                   W   Q   Q   R   G   P   S   V  
  IMGT000097 IGHA*01 F M gDNA     tgg cag cag aga ggg ccc tca gta c

This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).

Created:: 10/08/2022
Last updated:: 30/09/2022
Authors:: Turkan Samadova