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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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The Sandbar shark (Carcharhinus plumbeus) IGIV genes and allele have a temporary designation based on the IMGT gene name nomenclature rules for the unmapped genes, the incomplete loci, or the cDNAs in the absence of germline genes.
Sandbar shark (Carcharhinus plumbeus) genes are designated by a number for the subgroup followed by the letter S and a number.

IMGT subgroup IMGT gene name IMGT allele name Fct R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGIV1 IGIV1S1 IGIV1S1*01 (F) + + U11 U01657 [2] ~VJ
IGIV1S2 IGIV1S2*01 (F) + + T11 U34992 [3] ~VJ
IGIV1S3 IGIV1S3*01 (F) + + T46 U35006 [3] ~VJ
IGIV1S4 IGIV1S4*01 (F) + + U31 U35007 [3] ~VJ
IGIV1S5 IGIV1S5*01 (F) + + T54 U35008 [3] ~VJ
IGIV1S6 IGIV1S6*01 (F) + + Shlc5.1 M81314 [1] #c

#c: rearranged cDNA.
~VJ: VJ genomic DNA rearranged in the cassette.

IMGT references:
  1. [1] Hohman V.S. et al., Proc. Natl. Acad. Sci. U.S.A., 89, 276-280 (1992). PMID:1729697
  2. [2] Hohman V.S. et al., Proc. Natl. Acad. Sci. U.S.A., 90, 9882-9886 (1993). PMID:8234330
  3. [3] Hohman V.S. et al., J. Immunol., 155, 3922-3928 (1995). PMID:7561099
Created:
03/09/2003
Last updated:
22/09/2023
Authors:
Dominique Scaviner