IMGT Repertoire (IG and TR)


Locus representation: human (Homo sapiens) TRA/TRD locus on chromosome 14 (14q11.2) assembly HG02257_mat_hprc_f2

Citing this page: Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, London, 398 pages (2001)

Human (Homo sapiens) TRA/TRD locus on chromosome 14 (14q11.2) assembly HG02257_mat_hprc_f2

The orientation of the human (Homo sapiens) TRA/TRD locus on chromosome 14 (14q11.2) assembly HG02257_mat_hprc_f2 is forward (FWD).

Locus representation human (<em>Homo sapiens</em>) TRA/TRD locus on chromosome 14 (14q11.2) assembly HG02257_mat_hprc_f2

Legend:
Colors are according to IMGT color menu for genes.
The boxes representing the genes are not to scale. Exons are not shown.
A double slash // indicates a gap in genome assembly. Distances in bp (base pair) or in kb (kilobase) associated with a double slash are taken into account in the length of the lines and included in the numbers displayed at the right end of the lines.

TRA and TRD gene names are according to the IMGT nomenclature [1].
A small arrow shows a gene (TRDV3) whose polarity is opposite to that of the TRD D-J-C-CLUSTER.

Locus representation with only the functional genes: human (Homo sapiens) TRA/TRD locus on chromosome 14 (14q11.2) assembly HG02257_mat_hprc_f2

Gene localization is according to data from IMGT/LocusView.
This locus representation with only the functional genes is used with IMGT/GeneFrequency.

Locus representation human (<em>Homo sapiens</em>) TRA/TRD locus on chromosome 14 (14q11.2) assembly HG02257_mat_hprc_f2

* When needed, indicate the presence of allele(s) with another functionality: see above human (Homo sapiens) TRA/TRD locus on chromosome 14 (14q11.2) assembly HG02257_mat_hprc_f2

Zoom for J-C-CLUSTER

zoom

IMGT references:
  1. [1] Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, London, 398 pages (2001).
  2. [2] Lefranc, M.-P., Nomenclature of the human T cell receptor genes, Current Protocols in Immunology, A.1O.1-A.1O.23 (2000).
TRAV genes
  1. [3] Boysen, C. et al., unpublished (AE000658,AE000659,AE000660,AE000661).
TRAV alignments
  1. [4] Arden, B. et al., Immunogenetics, 42, 455-500 (1995).
TRAJ genes
  1. [5] Koop, B.F. et al., Genomics, 19, 478-493 (1994).
TRAC genes
  1. [6] Baer, R. et al., Mol. Biol. Med., 3, 265-277 (1986).
  2. [7] Yoshikai, Y. et al., Nature, 316, 837-840 (1985).
TRA enhancer (4,5 kb 3' from TRAC)
  1. [8] Ho, I.C. et al., Proc. Natl. Acad. Sci. USA, 86, 6714-6718 (1989).
TRDV genes
  1. [9] Boysen, C. et al., unpublished (AE000660,AE000661).
TRDD genes
  1. [10] Takihara, Y. et al., Proc. Natl. Acad. Sci. USA. 85, 6097-6101 (1988).
  2. [11] Loh, E.Y. et al., Proc. Natl. Acad. Sci. USA. 85, 9714-9718 (1988).
TRDJ genes
  1. [12] Isobe, M. et al., Proc. Natl. Acad. Sci. USA. 85, 3933-3937 (1988).
  2. [13] Loh, E.Y. et al., Proc. Natl. Acad. Sci. USA. 85, 9714-9718 (1988).
  3. [14] Satyanarayana, K. et al., Proc. Natl. Acad. Sci. USA. 85, 8166-8170 (1988).
TRDC genes
  1. [15] Takihara, Y. et al., Proc. Natl. Acad. Sci. USA. 85, 6097-6101 (1988).
TRD enhancer (between TRDJ3 and TRDC)
  1. [16] Redondo, J.M. et al., Science, 247, 1225-1229 (1990).
  2. [17] Bories, J.C. et al., J. Exp. Med. 171, 75-83 (1990).
Created:
20/01/2026
Last updated:
20/01/2026
Authors:
Mia Cherkaoui