IMGT Repertoire (IG and TR)
Reagents monoclonal antibodies: anti-mouse TRAV
This table lists reagents monoclonal antibodies, specific for the T cell Receptor Alpha Variable (TRAV) regions, which are commercially available.
The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the
'Clone name and Specificity' column.
The reactivities as described in this table are not exhaustive. For more information on the products and their reactivity, please contact the companies:
BD BioSciences Pharmingen, CEDARLANE laboratories Ltd.
- Germline gene table: Mouse (Mus musculus) TRAV
- Assignment of rearranged cDNAs and gDNAs to germline genes: Mouse (Mus musculus) TRAV
- Correspondence between the different gene nomenclatures: Mouse (Mus musculus) TRAV
Owing to the duplication of TRAV genes in the mouse TRA locus, the assignment of reagent monoclonal antibodies is only possible at the subgroup level.
TRAV haplotypes are shown with a superscript letter:
- a: A, AKR, BALB/c, C3H/He, CBA
- b: C57BL
- c: NOD, NZB, SJL, SWR
- d: DBA/1, DBA/2, NZW
| TRAV subgroup | Reagents monoclonal antibodies | |||||
|---|---|---|---|---|---|---|
| Clone name and Specificity | Company product | Species and Isotype | Strain host | Immunogen | ||
| TRAV1 | ||||||
| TRAV2 | ||||||
| TRAV3 | ||||||
| TRAV4 | RR8-1(TRAV4) | BD Pharmingen Vα11.1/Vα11.2b,d | Rat IgG2b,κ | Mouse T cell clone B10 | ||
| TRAV5 | ||||||
| TRAV6 | ||||||
| TRAV7 | ||||||
| TRAV8 | ||||||
| TRAV9 | RR3-16(TRAV9) | BD Pharmingen Vα3.2b,c | Rat IgG2b,κ | Fischer | Mouse cytotoxic T cell clone OH6 | |
| TRAV10 | ||||||
| TRAV11 | ||||||
| TRAV12 | KT50(TRAV12) | BD Pharmingen Vα8.3a,b,c,d | Rat IgG2a,κ | Sprague-Dawley (SD) | Mouse T cell clone C6 | |
| B21.14(TRAV12) | BD Pharmingen Vα8.3a,b,c,d | Rat IgG1,κ | LOU/W1 | Soluble TR αβ from mouse cytotoxic T cell clone CW3/1.1 | ||
| CTVA8(TRAV12) | CEDARLANE Vα8 | Rat IgG2a | ||||
| TRAV13 | ||||||
| TRAV14 | B20.1(TRAV14) | BD Pharmingen Vα2a,b,c | Rat IgG2a,λ | LOU/W1 | Soluble TR αβ from mouse cytotoxic T cell clone KB5-C20 | |
| B20.1(TRAV14) | CEDARLANE Vα2 | Rat IgG2a | ||||
| TRAV15 | ||||||
| TRAV16 | ||||||
| TRAV17 | ||||||
| TRAV18 | ||||||
| TRAV19 | ||||||
| TRAV20 | ||||||
| TRAV21 | ||||||
| TRAV22 | ||||||
| TRAV23 | ||||||
| Anti-idiotypic mab reagent | KJ1-26 (antiodiotypic for the TR αβ of Do11.10) | (1) | CEDARLANE | Mouse IgG2a | Mouse T cell hybridoma D011.10 | |
IMGT notes:
- (1) Binds the TR expressed on DO11.10 and DO11.10.24 murine T cell hybridomas. The TR expressed on DO11.10 recognizes an ovalbumin peptide in the context of I-Ad (MH2-AAd) [1,2]
IMGT references:
- Created:
- 04/10/2010
- Last updated:
- 22/09/2023
- Authors:
- Géraldine Folch
