IMGT/LIGM-DB logo
Database contains
247103 sequences
from 361 species

IMGT/LIGM-DB sequence

Version:
1.2.9
Database release:
LIGMDB_V12
Citing IMGT/LIGM-DB:
Giudicelli, V., Duroux P., Ginestoux C., Folch G., Jabado-Michaloud J., Chaume D., Lefranc M.-P., Nucleic Acids Res., 34:D781-D784 (2006). PMID:16381979 Abstract Full PDF

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Z13002 - Annotation

Sections
Accession number Z13002
Sequence version 1
Secondary accession numbers
IMGT annotation level by annotators
Definition O.aries rearranged T-cell receptor gamma
Species Ovis aries (sheep)
Taxonomy Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis; Ovis aries
Sequence length 537
IMGT/LIGM-DB dates 07-MAY-1996
  18-JAN-2013 (v. 6)

OBTENTION

Specificities
Disease related

IDENTIFICATION

Molecule type cDNA
Configuration type undefined, rearranged
Gene type constant, variable, joining
Molecule entity type L-V-J-C-sequence
Functionality type productive
Chain type TR-Gamma-TRG, TR-Gamma-3-TRGC3
Structure type regular
Location type
Other keywords antigen receptor, Immunoglobulin superfamily (IgSF), T cell receptor (TR), IMGT reference sequence

CLASSIFICATION

IMGT Groups TRGV
IMGT Subgroups TRGV2

DESCRIPTION

L-V-J-C-SEQUENCE   1..>537
  breed White Alpine
  cell_type peripheral lymphocytes
  dev_stage 6 month old thymectomized animal
  organism Ovis aries
5'UTR   1..85
L-V-J-C-REGION   86..>537
atgctgcgggccccagtgctgcttctggtgttcctggctcttgtcactcaggtatcttccaatatggaaggcgacaggatgtcaatcaccagggcagctgggtcctctactgtaatcccttgtgatcttcctacacaaaacatcaaatatatccactggtacaaattccaggagggaataccccgaggccttctctactatgatgtctcctactcaaaggttgtgttggaatcaggaatcagtccagggaaataccactgctatgaaggcacagacaagatatataaatttgtaatctcaagtcttcaagaaagtgattctggagtgtaccactgtgctgtctgggagaagctcgcgagttcaggctggaagaagatatttggaaaagcaactgagctcatagtagcttcccctgatagagaccttgatatagacatgtctcccaagcccac M L R A P V L L L V F L A L V T Q V S S N M E G D R M S I T R A A G S S T V I P C D L P T Q N I K Y I H W Y K F Q E G I P R G L L Y Y D V S Y S K V V L E S G I S P G K Y H C Y E G T D K I Y K F V I S S L Q E S D S G V Y H C A V W E K L A S S G W K K I F G K A T E L I V A S P D R D L D I D M S P K P
C C G P Q C C F W C S W L L S L R Y L P I W K A T G C Q S P G Q L G P L L * S L V I F L H K T S N I S T G T N S R R E Y P E A F S T M M S P T Q R L C W N Q E S V Q G N T T A M K A Q T R Y I N L * S Q V F K K V I L E C T T V L S G R S S R V Q A G R R Y L E K Q L S S * * L P L I E T L I * T C L P S P
A A G P S A A S G V P G S C H S G I F Q Y G R R Q D V N H Q G S W V L Y C N P L * S S Y T K H Q I Y P L V Q I P G G N T P R P S L L * C L L L K G C V G I R N Q S R E I P L L * R H R Q D I * I C N L K S S R K * F W S V P L C C L G E A R E F R L E E D I W K S N * A H S S F P * * R P * Y R H V S Q A H
L-V-J-REGION   86..499
atgctgcgggccccagtgctgcttctggtgttcctggctcttgtcactcaggtatcttccaatatggaaggcgacaggatgtcaatcaccagggcagctgggtcctctactgtaatcccttgtgatcttcctacacaaaacatcaaatatatccactggtacaaattccaggagggaataccccgaggccttctctactatgatgtctcctactcaaaggttgtgttggaatcaggaatcagtccagggaaataccactgctatgaaggcacagacaagatatataaatttgtaatctcaagtcttcaagaaagtgattctggagtgtaccactgtgctgtctgggagaagctcgcgagttcaggctggaagaagatatttggaaaagcaactgagctcatagtagcttcccct M L R A P V L L L V F L A L V T Q V S S N M E G D R M S I T R A A G S S T V I P C D L P T Q N I K Y I H W Y K F Q E G I P R G L L Y Y D V S Y S K V V L E S G I S P G K Y H C Y E G T D K I Y K F V I S S L Q E S D S G V Y H C A V W E K L A S S G W K K I F G K A T E L I V A S P
C C G P Q C C F W C S W L L S L R Y L P I W K A T G C Q S P G Q L G P L L * S L V I F L H K T S N I S T G T N S R R E Y P E A F S T M M S P T Q R L C W N Q E S V Q G N T T A M K A Q T R Y I N L * S Q V F K K V I L E C T T V L S G R S S R V Q A G R R Y L E K Q L S S * * L P
A A G P S A A S G V P G S C H S G I F Q Y G R R Q D V N H Q G S W V L Y C N P L * S S Y T K H Q I Y P L V Q I P G G N T P R P S L L * C L L L K G C V G I R N Q S R E I P L L * R H R Q D I * I C N L K S S R K * F W S V P L C C L G E A R E F R L E E D I W K S N * A H S S F P
L-V-REGION   86..433
  putative_limit 3' side
atgctgcgggccccagtgctgcttctggtgttcctggctcttgtcactcaggtatcttccaatatggaaggcgacaggatgtcaatcaccagggcagctgggtcctctactgtaatcccttgtgatcttcctacacaaaacatcaaatatatccactggtacaaattccaggagggaataccccgaggccttctctactatgatgtctcctactcaaaggttgtgttggaatcaggaatcagtccagggaaataccactgctatgaaggcacagacaagatatataaatttgtaatctcaagtcttcaagaaagtgattctggagtgtaccactgtgctgtctgggag M L R A P V L L L V F L A L V T Q V S S N M E G D R M S I T R A A G S S T V I P C D L P T Q N I K Y I H W Y K F Q E G I P R G L L Y Y D V S Y S K V V L E S G I S P G K Y H C Y E G T D K I Y K F V I S S L Q E S D S G V Y H C A V W E
C C G P Q C C F W C S W L L S L R Y L P I W K A T G C Q S P G Q L G P L L * S L V I F L H K T S N I S T G T N S R R E Y P E A F S T M M S P T Q R L C W N Q E S V Q G N T T A M K A Q T R Y I N L * S Q V F K K V I L E C T T V L S G
A A G P S A A S G V P G S C H S G I F Q Y G R R Q D V N H Q G S W V L Y C N P L * S S Y T K H Q I Y P L V Q I P G G N T P R P S L L * C L L L K G C V G I R N Q S R E I P L L * R H R Q D I * I C N L K S S R K * F W S V P L C C L G
L-REGION   86..139
atgctgcgggccccagtgctgcttctggtgttcctggctcttgtcactcaggta M L R A P V L L L V F L A L V T Q V
C C G P Q C C F W C S W L L S L R
A A G P S A A S G V P G S C H S G
INIT-CODON   86..88
V-J-C-REGION   140..>537
tcttccaatatggaaggcgacaggatgtcaatcaccagggcagctgggtcctctactgtaatcccttgtgatcttcctacacaaaacatcaaatatatccactggtacaaattccaggagggaataccccgaggccttctctactatgatgtctcctactcaaaggttgtgttggaatcaggaatcagtccagggaaataccactgctatgaaggcacagacaagatatataaatttgtaatctcaagtcttcaagaaagtgattctggagtgtaccactgtgctgtctgggagaagctcgcgagttcaggctggaagaagatatttggaaaagcaactgagctcatagtagcttcccctgatagagaccttgatatagacatgtctcccaagcccac S S N M E G D R M S I T R A A G S S T V I P C D L P T Q N I K Y I H W Y K F Q E G I P R G L L Y Y D V S Y S K V V L E S G I S P G K Y H C Y E G T D K I Y K F V I S S L Q E S D S G V Y H C A V W E K L A S S G W K K I F G K A T E L I V A S P D R D L D I D M S P K P
L P I W K A T G C Q S P G Q L G P L L * S L V I F L H K T S N I S T G T N S R R E Y P E A F S T M M S P T Q R L C W N Q E S V Q G N T T A M K A Q T R Y I N L * S Q V F K K V I L E C T T V L S G R S S R V Q A G R R Y L E K Q L S S * * L P L I E T L I * T C L P S P
F Q Y G R R Q D V N H Q G S W V L Y C N P L * S S Y T K H Q I Y P L V Q I P G G N T P R P S L L * C L L L K G C V G I R N Q S R E I P L L * R H R Q D I * I C N L K S S R K * F W S V P L C C L G E A R E F R L E E D I W K S N * A H S S F P * * R P * Y R H V S Q A H
V-J-REGION   140..499
tcttccaatatggaaggcgacaggatgtcaatcaccagggcagctgggtcctctactgtaatcccttgtgatcttcctacacaaaacatcaaatatatccactggtacaaattccaggagggaataccccgaggccttctctactatgatgtctcctactcaaaggttgtgttggaatcaggaatcagtccagggaaataccactgctatgaaggcacagacaagatatataaatttgtaatctcaagtcttcaagaaagtgattctggagtgtaccactgtgctgtctgggagaagctcgcgagttcaggctggaagaagatatttggaaaagcaactgagctcatagtagcttcccct S S N M E G D R M S I T R A A G S S T V I P C D L P T Q N I K Y I H W Y K F Q E G I P R G L L Y Y D V S Y S K V V L E S G I S P G K Y H C Y E G T D K I Y K F V I S S L Q E S D S G V Y H C A V W E K L A S S G W K K I F G K A T E L I V A S P
L P I W K A T G C Q S P G Q L G P L L * S L V I F L H K T S N I S T G T N S R R E Y P E A F S T M M S P T Q R L C W N Q E S V Q G N T T A M K A Q T R Y I N L * S Q V F K K V I L E C T T V L S G R S S R V Q A G R R Y L E K Q L S S * * L P
F Q Y G R R Q D V N H Q G S W V L Y C N P L * S S Y T K H Q I Y P L V Q I P G G N T P R P S L L * C L L L K G C V G I R N Q S R E I P L L * R H R Q D I * I C N L K S S R K * F W S V P L C C L G E A R E F R L E E D I W K S N * A H S S F P
V-REGION   140..433
  gene TRGV2S4
  putative_limit 3' side
tcttccaatatggaaggcgacaggatgtcaatcaccagggcagctgggtcctctactgtaatcccttgtgatcttcctacacaaaacatcaaatatatccactggtacaaattccaggagggaataccccgaggccttctctactatgatgtctcctactcaaaggttgtgttggaatcaggaatcagtccagggaaataccactgctatgaaggcacagacaagatatataaatttgtaatctcaagtcttcaagaaagtgattctggagtgtaccactgtgctgtctgggag S S N M E G D R M S I T R A A G S S T V I P C D L P T Q N I K Y I H W Y K F Q E G I P R G L L Y Y D V S Y S K V V L E S G I S P G K Y H C Y E G T D K I Y K F V I S S L Q E S D S G V Y H C A V W E
L P I W K A T G C Q S P G Q L G P L L * S L V I F L H K T S N I S T G T N S R R E Y P E A F S T M M S P T Q R L C W N Q E S V Q G N T T A M K A Q T R Y I N L * S Q V F K K V I L E C T T V L S G
F Q Y G R R Q D V N H Q G S W V L Y C N P L * S S Y T K H Q I Y P L V Q I P G G N T P R P S L L * C L L L K G C V G I R N Q S R E I P L L * R H R Q D I * I C N L K S S R K * F W S V P L C C L G
FR1-IMGT   140..217
  AA_IMGT 1 to 26
tcttccaatatggaaggcgacaggatgtcaatcaccagggcagctgggtcctctactgtaatcccttgtgatcttcct S S N M E G D R M S I T R A A G S S T V I P C D L P
L P I W K A T G C Q S P G Q L G P L L * S L V I F
F Q Y G R R Q D V N H Q G S W V L Y C N P L * S S
1st-CYS   206..208
CDR1-IMGT   218..235
  AA_IMGT AA 27 to 38, AA 30, 31, 32, 33, 34 and 35 are missing
acacaaaacatcaaatat T Q N I K Y
H K T S N
T K H Q I
FR2-IMGT   236..283
  AA_IMGT 39 to 55, AA50 missing
atccactggtacaaattccaggagggaataccccgaggccttctctac I H W Y K F Q E G I P R G L L Y
S T G T N S R R E Y P E A F S
P L V Q I P G G N T P R P S L
CONSERVED-TRP   242..244
CDR2-IMGT   284..307
  AA_IMGT AA 56 to 65, AA 60 and 61 are missing
tatgatgtctcctactcaaaggtt Y D V S Y S K V
M M S P T Q R
* C L L L K G
FR3-IMGT   308..421
  AA_IMGT 66 to 104, AA82 missing
gtgttggaatcaggaatcagtccagggaaataccactgctatgaaggcacagacaagatatataaatttgtaatctcaagtcttcaagaaagtgattctggagtgtaccactgt V L E S G I S P G K Y H C Y E G T D K I Y K F V I S S L Q E S D S G V Y H C
C W N Q E S V Q G N T T A M K A Q T R Y I N L * S Q V F K K V I L E C T T
V G I R N Q S R E I P L L * R H R Q D I * I C N L K S S R K * F W S V P L
2nd-CYS   419..421
CDR3-IMGT   422..463
  AA_IMGT AA 105 to 117, AA 112.1 is added
gctgtctgggagaagctcgcgagttcaggctggaagaagata A V W E K L A S S G W K K I
L S G R S S R V Q A G R R
C L G E A R E F R L E E D
JUNCTION   419..466
tgtgctgtctgggagaagctcgcgagttcaggctggaagaagatattt C A V W E K L A S S G W K K I F
V L S G R S S R V Q A G R R Y
C C L G E A R E F R L E E D I
N-REGION   434..442
aagctcgcg K L A
S S
A R
J-REGION   443..499
  gene TRGJ3
agttcaggctggaagaagatatttggaaaagcaactgagctcatagtagcttcccct S S G W K K I F G K A T E L I V A S P
V Q A G R R Y L E K Q L S S * * L P
F R L E E D I W K S N * A H S S F P
J-PHE   464..466
C-REGION   500..>537
  IMGT_gene TRGC3
gatagagaccttgatatagacatgtctcccaagcccac D R D L D I D M S P K P
I E T L I * T C L P S P
* R P * Y R H V S Q A H
EX1   500..>537
gatagagaccttgatatagacatgtctcccaagcccac D R D L D I D M S P K P
I E T L I * T C L P S P
* R P * Y R H V S Q A H

Literature references

[2] 1-537
Hein W.R.
Submitted to the ENA/GenBank/DDBJ databases (15-JUN-1992)
Wayne R. Hein, Basel Institute for Immunology, Grenzacherstrasse, 487, CH-4058 Basel, Switzerland
[3] 1-537
Hein W.R., Dudler L.
Divergent evolution of the T cell repertoire : extensive diversity and developmentally regulated expression of the sheep gamma/delta T cell receptor
EMBO J. 12:712-724 (1993)

Database cross-references

Database Identifiers Relation
ENA Z13002

Sequence

Length : 537 BP
Composition : 142 A; 129 C; 127 G; 139 T; 0 other

     agtctggtgg tctttaagag agatcctaga taactggggt gccggtcaca tctgctggga        60
     accccagctc attattgtcc cagccatgct gcgggcccca gtgctgcttc tggtgttcct       120
     ggctcttgtc actcaggtat cttccaatat ggaaggcgac aggatgtcaa tcaccagggc       180
     agctgggtcc tctactgtaa tcccttgtga tcttcctaca caaaacatca aatatatcca       240
     ctggtacaaa ttccaggagg gaataccccg aggccttctc tactatgatg tctcctactc       300
     aaaggttgtg ttggaatcag gaatcagtcc agggaaatac cactgctatg aaggcacaga       360
     caagatatat aaatttgtaa tctcaagtct tcaagaaagt gattctggag tgtaccactg       420
     tgctgtctgg gagaagctcg cgagttcagg ctggaagaag atatttggaa aagcaactga       480
     gctcatagta gcttcccctg atagagacct tgatatagac atgtctccca agcccac          537
Created:
23/07/1995
Database development:
Denys CHAUME, Patrice DUROUX, Nelly JOUFFRE
Database scientific officer:
Marie-Paule Lefranc