IMGT/LIGM-DB logo
Database contains
247103 sequences
from 361 species

IMGT/LIGM-DB sequence

Version:
1.2.9
Database release:
LIGMDB_V12
Citing IMGT/LIGM-DB:
Giudicelli, V., Duroux P., Ginestoux C., Folch G., Jabado-Michaloud J., Chaume D., Lefranc M.-P., Nucleic Acids Res., 34:D781-D784 (2006). PMID:16381979 Abstract Full PDF

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Z13006 - Annotation

Sections
Accession number Z13006
Sequence version 1
Secondary accession numbers
IMGT annotation level by annotators
Definition O.aries rearranged T-cell receptor gamma
Species Ovis aries (sheep)
Taxonomy Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis; Ovis aries
Sequence length 473
IMGT/LIGM-DB dates 07-MAY-1996
  18-JAN-2013 (v. 7)

OBTENTION

Specificities
Disease related

IDENTIFICATION

Molecule type cDNA
Configuration type undefined, rearranged
Gene type constant, variable, joining
Molecule entity type L-V-J-C-sequence
Functionality type productive
Chain type TR-Gamma-TRG, TR-Gamma-2-TRGC2
Structure type regular
Location type
Other keywords antigen receptor, Immunoglobulin superfamily (IgSF), T cell receptor (TR), IMGT reference sequence

CLASSIFICATION

IMGT Groups TRGV
IMGT Subgroups TRGV5

DESCRIPTION

L-V-J-C-SEQUENCE   1..>473
  breed White Alpine
  cell_type peripheral lymphocytes
  dev_stage 144 day old fetus
  organism Ovis aries
5'UTR   1..55
L-V-J-C-REGION   56..>473
atgcgggccccagcactggttctggttgtcttggctcccatcatgcaggtatcttccaacttgatgttaatcacgagaaagactggggagactgcttcgttcccttgtgatcttacacaaggggccacctatatccacttgtacaaacatgaggaggggatggccccccgacgccttttatactatgacagctacaactcaaagcctgtgtttgtatcaggaatctgtggaacaaaataccatgtctataagggcacagggaggagctatacatttgcgatcctaaatctgcaagcaagtgattccggcatatactactgtgctatctggacactctcgggctggaagaagatatttggagaaggagctaacatcatagtaactcctcccgagagaaaccttgctgcagacacttccc M R A P A L V L V V L A P I M Q V S S N L M L I T R K T G E T A S F P C D L T Q G A T Y I H L Y K H E E G M A P R R L L Y Y D S Y N S K P V F V S G I C G T K Y H V Y K G T G R S Y T F A I L N L Q A S D S G I Y Y C A I W T L S G W K K I F G E G A N I I V T P P E R N L A A D T S
C G P Q H W F W L S W L P S C R Y L P T * C * S R E R L G R L L R S L V I L H K G P P I S T C T N M R R G W P P D A F Y T M T A T T Q S L C L Y Q E S V E Q N T M S I R A Q G G A I H L R S * I C K Q V I P A Y T T V L S G H S R A G R R Y L E K E L T S * * L L P R E T L L Q T L P
A G P S T G S G C L G S H H A G I F Q L D V N H E K D W G D C F V P L * S Y T R G H L Y P L V Q T * G G D G P P T P F I L * Q L Q L K A C V C I R N L W N K I P C L * G H R E E L Y I C D P K S A S K * F R H I L L C Y L D T L G L E E D I W R R S * H H S N S S R E K P C C R H F
L-V-J-REGION   56..445
atgcgggccccagcactggttctggttgtcttggctcccatcatgcaggtatcttccaacttgatgttaatcacgagaaagactggggagactgcttcgttcccttgtgatcttacacaaggggccacctatatccacttgtacaaacatgaggaggggatggccccccgacgccttttatactatgacagctacaactcaaagcctgtgtttgtatcaggaatctgtggaacaaaataccatgtctataagggcacagggaggagctatacatttgcgatcctaaatctgcaagcaagtgattccggcatatactactgtgctatctggacactctcgggctggaagaagatatttggagaaggagctaacatcatagtaactcctccc M R A P A L V L V V L A P I M Q V S S N L M L I T R K T G E T A S F P C D L T Q G A T Y I H L Y K H E E G M A P R R L L Y Y D S Y N S K P V F V S G I C G T K Y H V Y K G T G R S Y T F A I L N L Q A S D S G I Y Y C A I W T L S G W K K I F G E G A N I I V T P P
C G P Q H W F W L S W L P S C R Y L P T * C * S R E R L G R L L R S L V I L H K G P P I S T C T N M R R G W P P D A F Y T M T A T T Q S L C L Y Q E S V E Q N T M S I R A Q G G A I H L R S * I C K Q V I P A Y T T V L S G H S R A G R R Y L E K E L T S * * L L
A G P S T G S G C L G S H H A G I F Q L D V N H E K D W G D C F V P L * S Y T R G H L Y P L V Q T * G G D G P P T P F I L * Q L Q L K A C V C I R N L W N K I P C L * G H R E E L Y I C D P K S A S K * F R H I L L C Y L D T L G L E E D I W R R S * H H S N S S
L-V-REGION   56..388
  putative_limit 3' side
atgcgggccccagcactggttctggttgtcttggctcccatcatgcaggtatcttccaacttgatgttaatcacgagaaagactggggagactgcttcgttcccttgtgatcttacacaaggggccacctatatccacttgtacaaacatgaggaggggatggccccccgacgccttttatactatgacagctacaactcaaagcctgtgtttgtatcaggaatctgtggaacaaaataccatgtctataagggcacagggaggagctatacatttgcgatcctaaatctgcaagcaagtgattccggcatatactactgtgctatctggaca M R A P A L V L V V L A P I M Q V S S N L M L I T R K T G E T A S F P C D L T Q G A T Y I H L Y K H E E G M A P R R L L Y Y D S Y N S K P V F V S G I C G T K Y H V Y K G T G R S Y T F A I L N L Q A S D S G I Y Y C A I W T
C G P Q H W F W L S W L P S C R Y L P T * C * S R E R L G R L L R S L V I L H K G P P I S T C T N M R R G W P P D A F Y T M T A T T Q S L C L Y Q E S V E Q N T M S I R A Q G G A I H L R S * I C K Q V I P A Y T T V L S G
A G P S T G S G C L G S H H A G I F Q L D V N H E K D W G D C F V P L * S Y T R G H L Y P L V Q T * G G D G P P T P F I L * Q L Q L K A C V C I R N L W N K I P C L * G H R E E L Y I C D P K S A S K * F R H I L L C Y L D
L-REGION   56..106
atgcgggccccagcactggttctggttgtcttggctcccatcatgcaggta M R A P A L V L V V L A P I M Q V
C G P Q H W F W L S W L P S C R
A G P S T G S G C L G S H H A G
INIT-CODON   56..58
V-J-C-REGION   107..>473
tcttccaacttgatgttaatcacgagaaagactggggagactgcttcgttcccttgtgatcttacacaaggggccacctatatccacttgtacaaacatgaggaggggatggccccccgacgccttttatactatgacagctacaactcaaagcctgtgtttgtatcaggaatctgtggaacaaaataccatgtctataagggcacagggaggagctatacatttgcgatcctaaatctgcaagcaagtgattccggcatatactactgtgctatctggacactctcgggctggaagaagatatttggagaaggagctaacatcatagtaactcctcccgagagaaaccttgctgcagacacttccc S S N L M L I T R K T G E T A S F P C D L T Q G A T Y I H L Y K H E E G M A P R R L L Y Y D S Y N S K P V F V S G I C G T K Y H V Y K G T G R S Y T F A I L N L Q A S D S G I Y Y C A I W T L S G W K K I F G E G A N I I V T P P E R N L A A D T S
L P T * C * S R E R L G R L L R S L V I L H K G P P I S T C T N M R R G W P P D A F Y T M T A T T Q S L C L Y Q E S V E Q N T M S I R A Q G G A I H L R S * I C K Q V I P A Y T T V L S G H S R A G R R Y L E K E L T S * * L L P R E T L L Q T L P
F Q L D V N H E K D W G D C F V P L * S Y T R G H L Y P L V Q T * G G D G P P T P F I L * Q L Q L K A C V C I R N L W N K I P C L * G H R E E L Y I C D P K S A S K * F R H I L L C Y L D T L G L E E D I W R R S * H H S N S S R E K P C C R H F
V-J-REGION   107..445
tcttccaacttgatgttaatcacgagaaagactggggagactgcttcgttcccttgtgatcttacacaaggggccacctatatccacttgtacaaacatgaggaggggatggccccccgacgccttttatactatgacagctacaactcaaagcctgtgtttgtatcaggaatctgtggaacaaaataccatgtctataagggcacagggaggagctatacatttgcgatcctaaatctgcaagcaagtgattccggcatatactactgtgctatctggacactctcgggctggaagaagatatttggagaaggagctaacatcatagtaactcctccc S S N L M L I T R K T G E T A S F P C D L T Q G A T Y I H L Y K H E E G M A P R R L L Y Y D S Y N S K P V F V S G I C G T K Y H V Y K G T G R S Y T F A I L N L Q A S D S G I Y Y C A I W T L S G W K K I F G E G A N I I V T P P
L P T * C * S R E R L G R L L R S L V I L H K G P P I S T C T N M R R G W P P D A F Y T M T A T T Q S L C L Y Q E S V E Q N T M S I R A Q G G A I H L R S * I C K Q V I P A Y T T V L S G H S R A G R R Y L E K E L T S * * L L
F Q L D V N H E K D W G D C F V P L * S Y T R G H L Y P L V Q T * G G D G P P T P F I L * Q L Q L K A C V C I R N L W N K I P C L * G H R E E L Y I C D P K S A S K * F R H I L L C Y L D T L G L E E D I W R R S * H H S N S S
V-REGION   107..388
  gene TRGV5S2
  putative_limit 3' side
tcttccaacttgatgttaatcacgagaaagactggggagactgcttcgttcccttgtgatcttacacaaggggccacctatatccacttgtacaaacatgaggaggggatggccccccgacgccttttatactatgacagctacaactcaaagcctgtgtttgtatcaggaatctgtggaacaaaataccatgtctataagggcacagggaggagctatacatttgcgatcctaaatctgcaagcaagtgattccggcatatactactgtgctatctggaca S S N L M L I T R K T G E T A S F P C D L T Q G A T Y I H L Y K H E E G M A P R R L L Y Y D S Y N S K P V F V S G I C G T K Y H V Y K G T G R S Y T F A I L N L Q A S D S G I Y Y C A I W T
L P T * C * S R E R L G R L L R S L V I L H K G P P I S T C T N M R R G W P P D A F Y T M T A T T Q S L C L Y Q E S V E Q N T M S I R A Q G G A I H L R S * I C K Q V I P A Y T T V L S G
F Q L D V N H E K D W G D C F V P L * S Y T R G H L Y P L V Q T * G G D G P P T P F I L * Q L Q L K A C V C I R N L W N K I P C L * G H R E E L Y I C D P K S A S K * F R H I L L C Y L D
FR1-IMGT   107..172
  AA_IMGT 1 to 26, AA5, 6, 7, 8 missing
tcttccaacttgatgttaatcacgagaaagactggggagactgcttcgttcccttgtgatcttaca S S N L M L I T R K T G E T A S F P C D L T
L P T * C * S R E R L G R L L R S L V I L
F Q L D V N H E K D W G D C F V P L * S Y
1st-CYS   161..163
CDR1-IMGT   173..187
  AA_IMGT AA 27 to 38, AA 30, 31, 32, 33, 34, 35 and 36 are missing
caaggggccacctat Q G A T Y
K G P P
R G H L
FR2-IMGT   188..238
  AA_IMGT 39 to 55
  note conserved TRP is replaced by LEU: ctg instead of tgg
atccacttgtacaaacatgaggaggggatggccccccgacgccttttatac I H L Y K H E E G M A P R R L L Y
S T C T N M R R G W P P D A F Y
P L V Q T * G G D G P P T P F I
CDR2-IMGT   239..262
  AA_IMGT AA 56 to 65, AA 60 and 61 are missing
tatgacagctacaactcaaagcct Y D S Y N S K P
M T A T T Q S
* Q L Q L K A
FR3-IMGT   263..376
  AA_IMGT 66 to 104, AA82 missing
gtgtttgtatcaggaatctgtggaacaaaataccatgtctataagggcacagggaggagctatacatttgcgatcctaaatctgcaagcaagtgattccggcatatactactgt V F V S G I C G T K Y H V Y K G T G R S Y T F A I L N L Q A S D S G I Y Y C
C L Y Q E S V E Q N T M S I R A Q G G A I H L R S * I C K Q V I P A Y T T
V C I R N L W N K I P C L * G H R E E L Y I C D P K S A S K * F R H I L L
2nd-CYS   374..376
CDR3-IMGT   377..409
  AA_IMGT AA 105 to 117, AA 111 and 112 are missing
gctatctggacactctcgggctggaagaagata A I W T L S G W K K I
L S G H S R A G R R
Y L D T L G L E E D
JUNCTION   374..412
tgtgctatctggacactctcgggctggaagaagatattt C A I W T L S G W K K I F
V L S G H S R A G R R Y
C Y L D T L G L E E D I
N-REGION   389..391
J-REGION   392..445
  gene TRGJ2
tcgggctggaagaagatatttggagaaggagctaacatcatagtaactcctccc S G W K K I F G E G A N I I V T P P
R A G R R Y L E K E L T S * * L L
G L E E D I W R R S * H H S N S S
J-PHE   410..412
C-REGION   446..>473
  IMGT_gene TRGC2
gagagaaaccttgctgcagacacttccc E R N L A A D T S
R E T L L Q T L P
E K P C C R H F
EX1   446..>473
gagagaaaccttgctgcagacacttccc E R N L A A D T S
R E T L L Q T L P
E K P C C R H F

Literature references

[2] 1-473
Hein W.R.
Submitted to the ENA/GenBank/DDBJ databases (15-JUN-1992)
Wayne R. Hein, Basel Institute for Immunology, Grenzacherstrasse, 487, CH-4058 Basel, Switzerland
[3] 1-473
Hein W.R., Dudler L.
Divergent evolution of the T cell repertoire : extensive diversity and developmentally regulated expression of the sheep gamma/delta T cell receptor
EMBO J. 12:712-724 (1993)

Database cross-references

Database Identifiers Relation
ENA Z13006

Sequence

Length : 473 BP
Composition : 122 A; 119 C; 112 G; 120 T; 0 other

     ttctctgcca gtcacatctg ctcagaattc cagtctagct gactgctggg gcaggatgcg        60
     ggccccagca ctggttctgg ttgtcttggc tcccatcatg caggtatctt ccaacttgat       120
     gttaatcacg agaaagactg gggagactgc ttcgttccct tgtgatctta cacaaggggc       180
     cacctatatc cacttgtaca aacatgagga ggggatggcc ccccgacgcc ttttatacta       240
     tgacagctac aactcaaagc ctgtgtttgt atcaggaatc tgtggaacaa aataccatgt       300
     ctataagggc acagggagga gctatacatt tgcgatccta aatctgcaag caagtgattc       360
     cggcatatac tactgtgcta tctggacact ctcgggctgg aagaagatat ttggagaagg       420
     agctaacatc atagtaactc ctcccgagag aaaccttgct gcagacactt ccc              473
Created:
23/07/1995
Database development:
Denys CHAUME, Patrice DUROUX, Nelly JOUFFRE
Database scientific officer:
Marie-Paule Lefranc