1417 entries
1234 -IG
7 -TR
47 -FPIA
68 -CPCA
61 -RPI
1234 -IG
7 -TR
47 -FPIA
68 -CPCA
61 -RPI
IMGT/mAb-DB card
Version: 2.0.4 (2023-04-14)
Citing IMGT/mAb-DB
Manso T., Kushwaha A., Abdollahi N., Duroux P., Giudicelli V. and Kossida S. Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB. Front Immunol., 14 (2023). DOI 10.3389/fimmu.2023.1129323
Poiron C., Wu Y., Ginestoux C., Ehrenmann, Duroux P. and Lefranc M.-P.
IMGT/mAb-DB: the IMGT® database for therapeutic monoclonal antibodies.
JOBIM 2010, Paper 13 (2010).
Abstract
Cambon M., Cherouali K., Kushwaha A., Giudicelli V., Duroux P., Kossida S. and Lefranc M.-P.
IMGT/mAb-DB and IMGT/2Dstructure-DB for IMGT standard definition of an antibody: from receptor to amino acid changes.
JOBIM 2018, Poster 201 (2018).
Abstract
| IMGT/mAb-DB ID | 501 |
| INN | emactuzumab |
| INN Number | 9951 |
| INN Prop. List | 111 (2014) |
| INN Rec. List | 73 (2015) |
| Common name | RG7155, RO5509554 |
| Proprietary name | |
| Species | Humanized |
| IMGT receptor type | IG |
| Format (legend) |  |
| Receptor identification | IgG1 - kappa |
| Radiolabelled / Conjugated / Fused | |
| IMGT/2Dstructure-DB | 9951 |
| IMGT/3Dstructure-DB | |
| Specificity target name and species | CSF1R (colony stimulating factor 1 receptor, CSF-1R, CSF-1-R, macrophage colony-stimulating factor 1 receptor, c-fms, FMS, CD115) [Humanized] |
| Development Technology | |
| Origin clone species | |
| Origin clone name | |
| Company | Roche, F. Hoffmann-La Roche Ltd. (Basel Switzerland) |
| Expression system | CHO (Chinese Hamster Ovary) cells |
| Application | Therapeutic |
| Clinical domain | Oncology |
| Mechanism of action | |
| Clinical indication | Solid tumors |
| Development status | Phase I |
| Regulatory agency status and year | |
| Clinical trials | |
| Authority decisions | |
| External links | |
| Biosimilars | |
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