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IMGT/mAb-DB card

Version: 2.0.4 (2023-04-14)

Citing IMGT/mAb-DB

Manso T., Kushwaha A., Abdollahi N., Duroux P., Giudicelli V. and Kossida S. Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB. Front Immunol., 14 (2023). DOI 10.3389/fimmu.2023.1129323

Poiron C., Wu Y., Ginestoux C., Ehrenmann, Duroux P. and Lefranc M.-P. IMGT/mAb-DB: the IMGT® database for therapeutic monoclonal antibodies. JOBIM 2010, Paper 13 (2010). Abstract PDF

Cambon M., Cherouali K., Kushwaha A., Giudicelli V., Duroux P., Kossida S. and Lefranc M.-P. IMGT/mAb-DB and IMGT/2Dstructure-DB for IMGT standard definition of an antibody: from receptor to amino acid changes. JOBIM 2018, Poster 201 (2018). Abstract PDF

IMGT/mAb-DB ID 501
INN emactuzumab
INN Number 9951
INN Prop. List 111 (2014)
INN Rec. List 73 (2015)
Common name RG7155, RO5509554
Proprietary name
Species Humanized
IMGT receptor type IG
Format (legend)
Receptor identification IgG1 - kappa
Radiolabelled / Conjugated / Fused
IMGT/2Dstructure-DB 9951
Specificity target name and species CSF1R (colony stimulating factor 1 receptor, CSF-1R, CSF-1-R, macrophage colony-stimulating factor 1 receptor, c-fms, FMS, CD115) [Humanized]
Development Technology
Origin clone species
Origin clone name

Company Roche, F. Hoffmann-La Roche Ltd. (Basel Switzerland)
Expression system CHO (Chinese Hamster Ovary) cells
Application Therapeutic
Clinical domain Oncology
Mechanism of action
Clinical indication Solid tumors
Development status Phase I
Regulatory agency status and year

    Clinical trials
    Authority decisions
      External links
        Format legend:

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