Version: 2.0.4 (2023-04-14)
Manso T., Kushwaha A., Abdollahi N., Duroux P., Giudicelli V. and Kossida S. Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB. Front Immunol., 14 (2023). DOI 10.3389/fimmu.2023.1129323
Poiron C., Wu Y., Ginestoux C., Ehrenmann, Duroux P. and Lefranc M.-P.
IMGT/mAb-DB: the IMGT® database for therapeutic monoclonal antibodies.
JOBIM 2010, Paper 13 (2010).
Abstract
Cambon M., Cherouali K., Kushwaha A., Giudicelli V., Duroux P., Kossida S. and Lefranc M.-P.
IMGT/mAb-DB and IMGT/2Dstructure-DB for IMGT standard definition of an antibody: from receptor to amino acid changes.
JOBIM 2018, Poster 201 (2018).
Abstract
IMGT/mAb-DB ID | 941 |
INN | avizakimab |
INN Number | 11148 |
INN Prop. List | 121 (2019) |
INN Rec. List | 83 (2020) |
Common name | BOS161721 |
Proprietary name | |
Species | Humanized |
IMGT receptor type | IG |
Format (legend) | ![]() |
Receptor identification | IgG1 - kappa |
Radiolabelled / Conjugated / Fused | |
IMGT/2Dstructure-DB | 11148 |
IMGT/3Dstructure-DB | |
Specificity target name and species | IL21 (interleukin 21) [Humanized] |
Development Technology | |
Origin clone species | |
Origin clone name | |
Company | Boston Pharmaceuticals (Cambridge MA USA) |
Expression system | CHO (Chinese Hamster Ovary) cells |
Application | Therapeutic |
Clinical domain | Immunology |
Mechanism of action | |
Clinical indication | Systemic lupus erythematosus (SLE) |
Development status | Phase I/II |
Regulatory agency status and year | |
Clinical trials | |
Authority decisions | |
External links | |
Biosimilars |