IMGT Lexique

Here you are: IMGT Web resources > IMGT Lexique

Mutation

Definition: a variation in a sequence.
Mutation type: a mutation in a nucleotide sequence can be a nucleotide substitution, a deletion or an insertion of one or several nucleotides. A mutation can be silent (no amino acid change) or nonsilent (amino acid change).
Transmission: mutations can be transmitted or not. Mutation which are transmitted represent allelic polymorphisms.
Physiopathological consequences: Mutations can or cannot be deleterious and causing or not diseases.

See also:

IMGT classes of the 20 common amino acids for the 'hydropathy', 'volume', 'chemical characteristics' properties