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QUESTION 6:

Are all the human TRA genes known?
How to analyse the expressed variable TRA genes?

ANSWER to question 6:

All the human TRA genes are known and well characterized. The human TRA genes were approved by the HUGO Nomenclature committee in 1999 (http://www.hugo-international.org/) and entered in the Genome Database GDB, Canada (http://www.ncbi.nlm.nih.gov/sites/genome) and into Entrez Gene (http://www.ncbi.nlm.nih.gov/gene) at NCBI, USA.
A complete list is available in the IMGT repertoire.

IMGT/GENE-DB an IMGT database for the human IG and TR genes

IMGT/V-QUEST, an IMGT tool for the analysis of the Variable genes, provides:

    1) the identification of the TRAV and TRAJ genes involved in the rearrangements,
    2) the characterization of the V-J-JUNCTION,
    3) the 2D representation or Collier de Perles.

Created: 11/06/2001
Last updated: Wednesday, 31-Jul-2024 17:53:33 CEST
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Editor: Elodie Foulquier