| Selectins | CD | HGNC gene name | Alias | Entrez Gene | Swiss-Prot | OMIM | Ligands | Ligand distribution | Fonction | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hematopoietic cells Platelets |
Neural cells | Endothelium Epithelium |
|||||||||
| L-selectin | CD62L | SELL | LSEL | 6402 | P14151 | 153240 | Sulfated: GlyCAM-1 CD34 MAdCAM-1 |
Leucocytes (Homing receptor) | |||
| E-selectin | CD62E | SELE | ESEL | 6401 | P16581 | 131210 | Tetrasaccharides: Sialyl-Lewisx Sialyl-Lewisa Cutaneous lymphocyte-associated antigen |
Endothelium | |||
| P-selectin | CD62P | SELP | PSEL | 6403 | P16109 | 173610 | Tetrasaccharides: Sialyl-Lewisx P-selectin glycoprotein ligand-1 |
Platelets | Endothelium | ||
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| Neu-IgCAM | CD | HGNC gene name | Alias | Entrez Gene | Swiss-Prot | OMIM | Ligands | Ligand distribution | Fonction | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hematopoietic Thymocyte |
Neural cells | Endothelial Epithelium |
|||||||||
| Adhesion molecule on glia (AMOG) | ATP1B2 | 482 | P14415 | 182331 | Glial | Neural migration | |||||
| L1CAM | CD171 | L1CAM | 3897 | P32004 | 308840 | Axonin | Neural | ||||
| Myelin-associated glycoprotein (MAG) |
MAG | 4099 | P20916 | 159460 | MAG | Myelin | |||||
| Myelin-oligodendrocyte glycoprotein (MOG) |
MOG | 4340 | Q16653 | 159465 | Myelin | Oligodendrocytes | |||||
| NCAM-1 | CD56 | NCAM1 | 4684 | P13591 | 116930 | NCAM-1 via polysialic acid Modulated by Sialyltransferase X Polysialyltransferase |
Neural | ||||
| NrCAM | NRCAM | 4897 | Q92823 | 601581 | Neural | ||||||
| Neurofascin | NFASC | 23114 | O94856 | 609145 | |||||||
| NgCAM (neural-glial CAM) | L1 | ||||||||||
| OBCAM | OPCML | OPCM | 4978 | Q14982 | 600632 | Opioids (μ) Acidic lipids |
Brain | ||||
| P0 | MPZ | 4359 | P25189 | 159440 | P0 | Myelin | |||||
| PMP-22 | PMP22 | 5376 | Q01453 | 601097 | PMP-22 | Myelin | |||||
| SynCAM | IGSF4 | 23705 | Q8N2F4 | 605686 | Neural Synapse |
||||||
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| Leu-IgCAM | CD | HGNC gene name | Alias | Entrez Gene | Swiss-Prot | OMIM | Ligands | Ligand distribution | Fonction | Disease | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hematopoietic Thymocyte |
Neural cells | Endothelial Epithelium |
||||||||||
| ALCAM | CD166 | ALCAM | 214 | Q13740 | 601662 | CD6, CD166 NgCAM 35 kD protein |
Leukocytes | Neural | ||||
| Basigin | CD147 | BSG | 682 | P35613 | 109480 | Leukocytes RBCs Platelets |
Endothelial | |||||
| BL-CAM | CD22 | CD22 | 933 | P20273 | 107266 | Sialylated glycoproteins LCA (CD45) |
B-Lymphocytes | |||||
| CD44 | CD44 | CD44 | 960 | P16070 | 107269 | Hyaluronin Ankyrin Fibronectin MIP1β Osteopontin |
Lymphocytes | WM perivascular astrocytes Glial tumors (malignant) Metastases (CD44v splice variant) |
Epithelial | |||
| ICAM-1 | CD54 | ICAM1 | 3383 | P05362 | 147840 | αLβ2 LFA-1 |
Leukocytes Dendritic cells |
Fibroblasts Synovial cells |
Endothelial cells Epithelium |
Disease: Lys29Met mutation Susceptibility to cerebral malaria |
||
| ICAM-2 | CD102 | ICAM2 | 3384 | P13598 | 146630 | αL/β2 (LFA-1) | Lymphocytes Monocytes |
Endothelial cells |
||||
| ICAM-3 | CD50 | ICAM3 | 3385 | P32942 | 146631 | αLβ2 | Leukocytes | |||||
| Lymphocyte function antigen-2 (LFA-2) |
CD2 | CD2 | 914 | P06729 | 186990 | LFA-3 | Lymphocytes Thymocytes |
|||||
| LFA-3 | CD58 | CD58 | 965 | P19256 | 153420 | LFA-2 | Leukocytes | Astrocytoma | Stroma Endothelial cells | |||
| Major histocompatibility complex (MHC) molecules |
||||||||||||
| MADCAM-1 | MADCAM1 | MACAM1 | 8174 | Q13477 | 102670 | α4β7 L-selectin |
Mucosal endothelial cells | |||||
| PECAM | CD31 | PECAM1 | 5175 | P16284 | 173445 | CD31 αv β3 |
Leukocytes | Synovial cells | Endothelial cells | |||
| T-cell receptor (C-region) |
TRAC | 28755 | ||||||||||
| VCAM-1 | CD106 | VCAM1 | 7412 | P19320 | 192225 | α4β1 α4β7 |
Monocytes | Satellite cells Synovial cells |
Activated endothelial cells | |||
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