IMGT®, the international ImMunoGeneTics information system®

Domain type and domain set

Domain type

The 'domain type' concept identifies the type of a domain. A domain is a subunit of a chain characterized by its three-dimensional (3D structure).

The 'domain type' concept is part of the 'IDENTIFICATION' concept of IMGT-ONTOLOGY [1]

In IMGT, the 'domain type' concept has three main concepts:

• the V type (V for variable)
• the C type (C for constant)
• the G type (G for groove)
  • 'V type' identifies the domain type of domains described as V-DOMAIN and V-LIKE-DOMAIN (Table) [2].
  • 'C type' identifies the domain type of domains described as C-DOMAIN and C-LIKE-DOMAIN (Table) [3].
  • 'G type' identifies the domain type of domains described as G-DOMAIN and G-LIKE-DOMAIN (Table) [4].

Domain set

Domain sequences or domain structures (in reality) that are identified by a given 'domain type' concept make up a given domain set. Thus:

• 'V set' refers to a set of domain sequences or structures (in reality) that are identified by the 'V type' concept.
• 'C set' refers to a set of domain sequences or structures (in reality) that are identified by the 'C type' concept.
• 'G set' refers to a set of domain sequences or structures (in reality) that are identified by the 'G type' concept.