IMGT®, the international ImMunoGeneTics information system®

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IMGT/PROTEIN-DB (in development)

IMGT/PROTEIN-DB (in development) will be a new database related to immunoglobulin and T cell receptor amino acid sequences in the IMGT, the international ImMunoGeneTics information system® http://www.imgt.org.

IMGT/PROTEIN-DB will allow a search per protein name and will be based on the CLASSIFICATION concept of IMGT-ONTOLOGY.

Although the implementation is still in progress, information on the translation of IG and TR genes and alleles is already available in IMGT Repertoire > Proteins and alleles [1-4].

Information on 3D structures is available in IMGT Repertoire > 2D and 3D structures and in IMGT/3Dstructure-DB.

The human IMGT IG and TR nomenclature [1-2] was approved by the HUman Genome Organization (HUGO) Gene Nomenclature Committee (HGNC) in 1999.

References:
[1] Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, 458 pages (2001), ISBN: 012441351X
[2] Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, 398 pages (2001), ISBN: 0124413528
[3] Folch, G., Scaviner, D., Contet, V. and Lefranc, M.-P., Exp. Clin. Immunogenet., 17, 205-215 (2000), PMID: 11096259, LIGM:236 pdf
[4] Scaviner, D., Barbié, V., Ruiz, M. and Lefranc, M.-P., Exp. Clin. Immunogenet., 16, 234-240 (1999), PMID: 10575277, LIGM:218 pdf